Search Results - "Subbiah, N."

The diagnostic role of T wave morphology biomarkers in congenital and acquired long QT syndrome: A systematic review by Tardo, Daniel T., Peck, Matthew, Subbiah, Rajesh N., Vandenberg, Jamie I., Hill, Adam. P.

“…Introduction QTc prolongation is key in diagnosing long QT syndrome (LQTS), however 25%–50% with congenital LQTS (cLQTS) demonstrate a normal resting QTc. T…”
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Left Atrial Appendage Closure Guided by Personalized 3D-Printed Cardiac Reconstruction by Otton, James M., MBBS, PhD, Spina, Roberto, MBBS, Sulas, Romina, BEng, Subbiah, Rajesh N., MBBS, PhD, Jacobs, Neil, MBBS, Muller, David W.M., MBBS, MD, Gunalingam, Brendan, MBBS

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Human ether-a-go-go related gene (hERG) K+ channels: Function and dysfunction by Perrin, Mark J., Subbiah, Rajesh N., Vandenberg, Jamie I., Hill, Adam P.

“…The human Ether-a-go-go Related Gene (hERG) potassium channel plays a central role in regulating cardiac excitability and maintenance of normal cardiac rhythm…”
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Granulomatous sarcoid aortitis: a serious complication of a well-known multisystem disease by Wang, Louis W, Dr, Omari, Abdullah, Prof, Emmett, Louise, MD, Jansz, Paul C, PhD, Huilgol, Ravi, MBBS, Rainer, Stephen, MBChB, Subbiah, Rajesh N, PhD

“…In March, 2013, because of the thoracic aortic aneurysm size, presence of active disease, and risk of aneurysmal expansion and rupture, he had aortic…”
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Heritability of ECG Biomarkers in the Netherlands Twin Registry Measured from Holter ECGs by Hodkinson, Emily C, Neijts, Melanie, Sadrieh, Arash, Imtiaz, Mohammad S, Baumert, Mathias, Subbiah, Rajesh N, Hayward, Christopher S, Boomsma, Dorret, Willemsen, Gonneke, Vandenberg, Jamie I, Hill, Adam P, De Geus, Eco

“…The resting ECG is the most commonly used tool to assess cardiac electrophysiology. Previous studies have estimated heritability of ECG parameters based on…”
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Tryptophan scanning mutagenesis of the HERG K+ channel: the S4 domain is loosely packed and likely to be lipid exposed by Subbiah, Rajesh N., Kondo, Mari, Campbell, Terence J., Vandenberg, Jamie I.

“…Inherited mutations or drug-induced block of voltage-gated ion channels, including the human ether-à-go-go- related gene (HERG) K + channel, are significant…”
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Coronary Artery Embolization After Successful Surgical Ablation of Atrial Fibrillation by WANG, Louis W, OMARI, Abdullah, MULLER, David W. M, JACOBS, Neil H, SUBBIAH, Rajesh N

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Pulmonary arteriovenous malformation: an unusual cause of exertional dyspnoea by Wang, Louis W, Dr, Kotlyar, Eugene, MD, Bester, Lourens, MMed, Feneley, Michael P, Prof, Omari, Abdullah, Prof, Subbiah, Rajesh N, PhD

“…PAVMs are usually congenital in origin, but may be acquired in various conditions, such as cirrhosis, trauma, mitral stenosis, and schistosomiasis.1 Although…”
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Esophageal T-tube: A novel approach to atrioesophageal fistula repair by Kerr, Nicholas, Granger, Emily, Jansz, Paul, Fenton-Lee, Douglas, Feneley, Michael, Subbiah, Rajesh N.

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Molecular basis of slow activation of the human ether-á-go-go related gene potassium channel by Subbiah, Rajesh N., Clarke, Catherine E., Smith, David J., Zhao, JingTing, Campbell, Terence J., Vandenberg, Jamie I.

“…The human ether-á-go-go related gene ( HERG ) encodes the pore forming α-subunit of the rapid delayed rectifier K + channel which is central to the…”
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Unusual adverse consequence of reverse ventricular remodelling following cardiac resynchronization therapy by Chia, Pow-Li, Subbiah, Rajesh N, Kuchar, Dennis, Walker, Bruce

“…Cardiac resynchronization therapy has been shown to produce reverse ventricular remodelling in patients with severe heart failure. We report an unusual case of…”
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Associated factors with cervical pre-malignant lesions among the married fisher women community at Sadras, Tamil Nadu by Ganesan, Sornam, Subbiah, Vasantha N., Michael, Jothi Clara J.

“…Objective: To identify the associated factors of cervical pre-malignant lesions among the married fisher women residing in the coastal areas of Sadras, Tamil…”
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Andersen‐Tawil Syndrome: Management Challenges During Pregnancy, Labor, and Delivery by SUBBIAH, RAJESH N., GULA, LORNE J., SKANES, ALLAN C., KRAHN, ANDREW D.

“…Andersen‐Tawil syndrome (ATS) is characterized by ventricular arrhythmias, hypokalemic periodic paralysis and developmental anomalies. It is caused by…”
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Torsades de pointes during complete atrioventricular block: Genetic factors and electrocardiogram correlates by Subbiah, Rajesh N., BSc(Med) MBBS PhD, Gollob, Michael H., MD, Gula, Lorne J., MSc MD, Davies, Robert W., BSc, Leong-Sit, Peter, MD, Skanes, Allan C., MD, Yee, Raymond, MD, Klein, George J., MD, Krahn, Andrew D., MD

“…Introduction Atrioventricular (AV) block is infrequently associated with QT prolongation and torsades de pointes (TdP). It was hypothesized that patients with…”
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Reduction of complex ventricular ectopy and improvement in exercise capacity with flecainide therapy in Andersen-Tawil syndrome by Fox, David J., Klein, George J., Hahn, Angelika, Skanes, Allan C., Gula, Lorne J., Yee, Raymond K., Subbiah, Rajesh N., Krahn, Andrew D.

“…Andersen-Tawil syndrome (ATS) is a rare inherited autosomal disorder characterized by the clinical triad of ventricular arrhythmias, hypokalaemic periodic…”
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Cardiac sarcoidosis masquerading as arrhythmogenic right ventricular cardiomyopathy by Chia, Pow-Li, M.Med(Int Med), Subbiah, Rajesh N., PhD, Kuchar, Dennis, MD, Walker, Bruce, PhD

“…We present a case of ventricular tachycardia with clinical features suggestive of arrhythmogenic right ventricular cardiomyopathy. However, endomyocardial…”
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Action Potential Morphology Accurately Predicts Proarrhythmic Risk for Drugs With Potential to Prolong Cardiac Repolarization by Lee, William, Ng, Ben, Mangala, Melissa M., Perry, Matthew D., Subbiah, Rajesh N., Vandenberg, Jamie I., Hill, Adam P.

“…Drug-induced or acquired long QT syndrome occurs as a result of the unintended disruption of cardiac repolarization due to drugs that block cardiac ion…”
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Expression of a Common LQT1 Mutation in Five Apparently Unrelated Families in a Regional Inherited Arrhythmia Clinic by GRAY, CHRISTOPHER, GULA, LORNE J., KLEIN, GEORGE J., SKANES, ALLAN C., YEE, RAYMOND, SY, RAYMOND, SALISBURY, BENJAMIN A., WONG, JORGE, CHATTHA, ISHVINDER, SUBBIAH, RAJESH N., KRAHN, ANDREW D.

“…Expression of a Common LQT1 Mutation. Background: The Inherited Arrhythmia Clinic at the University of Western Ontario services a catchment area of 1.5 million…”
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Profound bradycardia and hypotension in a normal heart by Lee, William, BSc, MB BS (Hons), Gould, Paul A., MB BS (Hons), PhD, FRACP, Kuchar, Dennis L., MB BS (Hons), MD, FRACP, Subbiah, Rajesh N., BSc (Med), MB BS, PhD, FRACP

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Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2 by Sadrieh, Arash, Domanski, Luke, Pitt-Francis, Joe, Mann, Stefan A, Hodkinson, Emily C, Ng, Chai-Ann, Perry, Matthew D, Taylor, John A, Gavaghan, David, Subbiah, Rajesh N, Vandenberg, Jamie I, Hill, Adam P

“…The heart rhythm disorder long QT syndrome (LQTS) can result in sudden death in the young or remain asymptomatic into adulthood. The features of the surface…”
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