Search Results - "Suarez, Maria F"
-
1
Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B
Published in The EMBO journal (02-06-2020)“…Two mitotic cyclin types, cyclin A and B, exist in higher eukaryotes, but their specialised functions in mitosis are incompletely understood. Using degron tags…”
Get full text
Journal Article -
2
Transcriptional stimulation of rate-limiting components of the autophagic pathway improves plant fitness
Published in Journal of experimental botany (14-03-2018)“…Autophagy-related proteins Atg5 and Atg7 are rate-limiting components of autophagic flux in Arabidopsis. Overexpression of ATG5 or ATG7 genes stimulates Atg8…”
Get full text
Journal Article -
3
Two Interlinked Bistable Switches Govern Mitotic Control in Mammalian Cells
Published in Current biology (03-12-2018)“…Distinct protein phosphorylation levels in interphase and M phase require tight regulation of Cdk1 activity [1, 2]. A bistable switch, based on positive…”
Get full text
Journal Article -
4
Autophagy and metacaspase determine the mode of cell death in plants
Published in The Journal of cell biology (23-12-2013)“…Although animals eliminate apoptotic cells using macrophages, plants use cell corpses throughout development and disassemble cells in a cell-autonomous manner…”
Get full text
Journal Article -
5
Genetic background determines severity of Loxl1-mediated systemic and ocular elastosis in mice
Published in Disease models & mechanisms (01-11-2023)“…Pseudoexfoliation syndrome (PEX) is a systemic, age-related disorder characterized by elastosis and extracellular matrix deposits. Its most significant ocular…”
Get full text
Journal Article -
6
Autophagy mediates caloric restriction‐induced lifespan extension in Arabidopsis
Published in Aging cell (01-04-2013)“…Summary Caloric restriction (CR) extends lifespan in various heterotrophic organisms ranging from yeasts to mammals, but whether a similar phenomenon occurs in…”
Get full text
Journal Article -
7
Cysteine protease mcII-Pa executes programmed cell death during plant embryogenesis
Published in Proceedings of the National Academy of Sciences - PNAS (04-10-2005)“…Programmed cell death (PCD) is indispensable for eukaryotic development. In animals, PCD is executed by the caspase family of cysteine proteases. Plants do not…”
Get full text
Journal Article -
8
EXTRA SPINDLE POLES (Separase) controls anisotropic cell expansion in Norway spruce (Picea abies) embryos independently of its role in anaphase progression
Published in The New phytologist (01-10-2016)“…The caspase-related protease separase (EXTRA SPINDLE POLES, ESP) plays a major role in chromatid disjunction and cell expansion in Arabidopsis thaliana…”
Get full text
Journal Article -
9
Lysyl oxidase-like 1-antisense 1 (LOXL1-AS1) lncRNA differentially regulates gene and protein expression, signaling and morphology of human ocular cells
Published in Human molecular genetics (17-10-2023)“…Pseudoexfoliation glaucoma (PEXG) is characterized by dysregulated extracellular matrix (ECM) homeostasis that disrupts conventional outflow function and…”
Get full text
Journal Article -
10
Tudor staphylococcal nuclease is an evolutionarily conserved component of the programmed cell death degradome
Published in Nature cell biology (01-11-2009)“…Programmed cell death (PCD) is executed by proteases, which cleave diverse proteins thus modulating their biochemical and cellular functions. Proteases of the…”
Get full text
Journal Article -
11
Metacaspase-dependent programmed cell death is essential for plant embryogenesis
Published in Current biology (04-05-2004)Get full text
Journal Article -
12
Pro-inflammatory cytokines and gelatinases in climatic droplet keratopathy
Published in Investigative ophthalmology & visual science (14-06-2012)“…Climatic droplet keratopathy (CDK) is a degenerative disease of the cornea with possible involvement from matrix metalloproteinases (MMPs). Therefore, the…”
Get full text
Journal Article -
13
Genetic background and climatic droplet keratopathy incidence in a Mapuche population from Argentina
Published in PloS one (05-09-2013)“…To determine whether the incidence of and susceptibility to climatic droplet keratopathy (CDK), an acquired, often bilateral degenerative corneal disease, is…”
Get full text
Journal Article -
14
Programmed Cell Death in Plant Embryogenesis
Published in Current Topics in Developmental Biology (2005)“…Successful embryonic development in plants, as in animals, requires a strict coordination of cell proliferation, cell differentiation, and cell‐death programs…”
Get full text
Book Chapter Journal Article -
15
Chromosomal instability and inflammation: a catch-22 for cancer cells
Published in Chromosome research (10-08-2023)“…Chromosomal instability (CIN), an increased rate of chromosomal segregation abnormalities, drives intratumor heterogeneity and affects most human cancers. In…”
Get full text
Journal Article -
16
Variation in transcript abundance during somatic embryogenesis in gymnosperms
Published in Tree physiology (01-10-2004)“…Somatic embryogenesis of Norway spruce (Picea abies L.) is a versatile model system to study molecular mechanisms regulating embryo development because it…”
Get full text
Journal Article -
17
Detection and measurement of necrosis in plants
Published in Methods in molecular biology (Clifton, N.J.) (2013)“…Necrosis plays a fundamental role in plant physiology and pathology. When plants or plant cell cultures are subjected to abiotic stress they initiate rapid…”
Get more information
Journal Article -
18
Combined treatment with statins and aminobisphosphonates extends longevity in a mouse model of human premature aging
Published in Nature Medicine (01-07-2008)“…Several human progerias, including Hutchinson-Gilford progeria syndrome (HGPS), are caused by the accumulation at the nuclear envelope of farnesylated forms of…”
Get full text
Journal Article Magazine Article -
19
ATG4D role in mAtg8s delipidation and neuroprotection
Published in Autophagy (03-06-2021)Get full text
Journal Article -
20
Analysis of ATG4C function in vivo
Published in Autophagy (02-11-2023)“…Despite the great advances in macroautophagy/autophagy research in the last years, the in vivo role of the different members of the four mammalian orthologs of…”
Get full text
Journal Article