Search Results - "Su, Zhangli"

Noncanonical Roles of tRNAs: tRNA Fragments and Beyond by Su, Zhangli, Wilson, Briana, Kumar, Pankaj, Dutta, Anindya

“…As one of the most abundant and conserved RNA species, transfer RNAs (tRNAs) are well known for their role in reading the codons on messenger RNAs and…”
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TRMT6/61A-dependent base methylation of tRNA-derived fragments regulates gene-silencing activity and the unfolded protein response in bladder cancer by Su, Zhangli, Monshaugen, Ida, Wilson, Briana, Wang, Fengbin, Klungland, Arne, Ougland, Rune, Dutta, Anindya

“…RNA modifications are important regulatory elements of RNA functions. However, most genome-wide mapping of RNA modifications has focused on messenger RNAs and…”
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tRNA fragments (tRFs) guide Ago to regulate gene expression post-transcriptionally in a Dicer-independent manner by Kuscu, Canan, Kumar, Pankaj, Kiran, Manjari, Su, Zhangli, Malik, Asrar, Dutta, Anindya

“…tRNA related RNA fragments (tRFs), also known as tRNA-derived RNAs (tdRNAs), are abundant small RNAs reported to be associated with Argonaute proteins, yet…”
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Structural analysis of cross α-helical nanotubes provides insight into the designability of filamentous peptide nanomaterials by Wang, Fengbin, Gnewou, Ordy, Modlin, Charles, Beltran, Leticia C., Xu, Chunfu, Su, Zhangli, Juneja, Puneet, Grigoryan, Gevorg, Egelman, Edward H., Conticello, Vincent P.

“…The exquisite structure-function correlations observed in filamentous protein assemblies provide a paradigm for the design of synthetic peptide-based…”
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XRN2 suppresses aberrant entry of tRNA trailers into argonaute in humans and Arabidopsis by Wilson, Briana, Su, Zhangli, Kumar, Pankaj, Dutta, Anindya

“…MicroRNAs (miRNAs) are a well-characterized class of small RNAs (sRNAs) that regulate gene expression post-transcriptionally. miRNAs function within a complex…”
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The structures of two archaeal type IV pili illuminate evolutionary relationships by Wang, Fengbin, Baquero, Diana P., Su, Zhangli, Beltran, Leticia C., Prangishvili, David, Krupovic, Mart, Egelman, Edward H.

“…We have determined the cryo-electron microscopic (cryo-EM) structures of two archaeal type IV pili (T4P), from Pyrobaculum arsenaticum and Saccharolobus…”
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Integrative analysis of DNA replication origins and ORC-/MCM-binding sites in human cells reveals a lack of overlap by Tian, Mengxue, Wang, Zhenjia, Su, Zhangli, Shibata, Etsuko, Shibata, Yoshiyuki, Dutta, Anindya, Zang, Chongzhi

“…Based on experimentally determined average inter-origin distances of ~100 kb, DNA replication initiates from ~50,000 origins on human chromosomes in each cell…”
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ATAC-seq identifies thousands of extrachromosomal circular DNA in cancer and cell lines by Kumar, Pankaj, Kiran, Shashi, Saha, Shekhar, Su, Zhangli, Paulsen, Teressa, Chatrath, Ajay, Shibata, Yoshiyuki, Shibata, Etsuko, Dutta, Anindya

“…Extrachromosomal circular DNAs (eccDNAs) are somatically mosaic and contribute to intercellular heterogeneity in normal and tumor cells. Because short eccDNAs…”
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A packing for A-form DNA in an icosahedral virus by Wang, Fengbin, Liu, Ying, Su, Zhangli, Osinski, Tomasz, de Oliveira, Guilherme A. P., Conway, James F., Schouten, Stefan, Krupovic, Mart, Prangishvili, David, Egelman, Edward H.

“…Studies on viruses infecting archaea living in the most extreme environments continue to show a remarkable diversity of structures, suggesting that the…”
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tRNA-derived fragments and microRNAs in the maternal-fetal interface of a mouse maternal-immune-activation autism model by Su, Zhangli, Frost, Elizabeth L., Lammert, Catherine R., Przanowska, Roza K., Lukens, John R., Dutta, Anindya

“…tRNA-derived small fragments (tRFs) and tRNA halves have emerging functions in different biological pathways, such as regulating gene expression, protein…”
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Characterization of novel small non-coding RNAs and their modifications in bladder cancer using an updated small RNA-seq workflow by Su, Zhangli, Monshaugen, Ida, Klungland, Arne, Ougland, Rune, Dutta, Anindya

“…Bladder cancer (BLCA) is one of the most common cancer types worldwide. The disease is responsible for about 200,000 deaths annually, thus improved diagnostics…”
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ATAC-Seq-based Identification of Extrachromosomal Circular DNA in Mammalian Cells and Its Validation Using Inverse PCR and FISH by Su, Zhangli, Saha, Shekhar, Paulsen, Teressa, Kumar, Pankaj, Dutta, Anindya

“…Recent studies from multiple labs including ours have demonstrated the importance of extrachromosomal circular DNA (eccDNA) from yeast to humans ( Shibata ,…”
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sRNA-Effector: A tool to expedite discovery of small RNA regulators by Wilson, Briana, Esmaeili, Fatemeh, Parsons, Matthew, Salah, Wafa, Su, Zhangli, Dutta, Anindya

“…microRNAs (miRNAs) are small regulatory RNAs that repress target mRNA transcripts through base pairing. Although the mechanisms of miRNA production and…”
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Reader domain specificity and lysine demethylase-4 family function by Su, Zhangli, Wang, Fengbin, Lee, Jin-Hee, Stephens, Kimberly E., Papazyan, Romeo, Voronina, Ekaterina, Krautkramer, Kimberly A., Raman, Ana, Thorpe, Jeremy J., Boersma, Melissa D., Kuznetsov, Vyacheslav I., Miller, Mitchell D., Taverna, Sean D., Phillips, George N., Denu, John M.

“…The KDM4 histone demethylases are conserved epigenetic regulators linked to development, spermatogenesis and tumorigenesis. However, how the KDM4 family…”
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The pan-cancer landscape of prognostic germline variants in 10,582 patients by Chatrath, Ajay, Przanowska, Roza, Kiran, Shashi, Su, Zhangli, Saha, Shekhar, Wilson, Briana, Tsunematsu, Takaaki, Ahn, Ji-Hye, Lee, Kyung Yong, Paulsen, Teressa, Sobierajska, Ewelina, Kiran, Manjari, Tang, Xiwei, Li, Tianxi, Kumar, Pankaj, Ratan, Aakrosh, Dutta, Anindya

“…While clinical factors such as age, grade, stage, and histological subtype provide physicians with information about patient prognosis, genomic data can…”
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Depletion of the m1A writer TRMT6/TRMT61A reduces proliferation and resistance against cellular stress in bladder cancer by Monshaugen, Ida, Luna, Luisa, Rhodes, Jayden, Kristiansen, Felicia Iselin Svensson, Lång, Anna, Bøe, Stig Ove, Dutta, Anindya, Su, Zhangli, Klungland, Arne, Ougland, Rune

“…Bladder cancer (BLCA) is a common and deadly disease that results in a reduced quality of life for the patients and a significant economic burden on society. A…”
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Binding of the Fkh1 Forkhead Associated Domain to a Phosphopeptide within the Mph1 DNA Helicase Regulates Mating-Type Switching in Budding Yeast by Dummer, Antoinette M, Su, Zhangli, Cherney, Rachel, Choi, Koyi, Denu, John, Zhao, Xiaolan, Fox, Catherine A

“…The Saccharomyces cerevisiae Fkh1 protein has roles in cell-cycle regulated transcription as well as a transcription-independent role in recombination donor…”
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De-stressing the T cells in need by Su, Zhangli, Dutta, Anindya

“…Protection of transfer RNAs from fragmentation avoids overstressing T cells When exposed to external antigens, T cells are rapidly activated to proliferate and…”
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Angiogenin generates specific stress-induced tRNA halves and is not involved in tRF-3–mediated gene silencing by Su, Zhangli, Kuscu, Canan, Malik, Asrar, Shibata, Etsuko, Dutta, Anindya

“…tRNA fragments (tRFs) and tRNA halves have been implicated in various cellular processes, including gene silencing, translation, stress granule assembly, cell…”
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Reading the Combinatorial Histone Language by Su, Zhangli, Denu, John M

“…Histones are subject to frequent combinatorial post-translational modifications (PTMs), forming a complex chemical “language” that is interpreted by…”
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