Search Results - "Su, Yourong S."
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PIK3CA and CCM mutations fuel cavernomas through a cancer-like mechanism
Published in Nature (London) (10-06-2021)“…Vascular malformations are thought to be monogenic disorders that result in dysregulated growth of blood vessels. In the brain, cerebral cavernous…”
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Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1
Published in Proceedings of the National Academy of Sciences - PNAS (07-07-2015)“…Accumulation of the signaling protein Smoothened (Smo) in the membrane of primary cilia is an essential step in Hedgehog (Hh) signal transduction, yet the…”
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Engineered knottin peptide enables noninvasive optical imaging of intracranial medulloblastoma
Published in Proceedings of the National Academy of Sciences - PNAS (03-09-2013)“…Central nervous system tumors carry grave clinical prognoses due to limited effectiveness of surgical resection, radiation, and chemotherapy. Thus, improved…”
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mTORC1 Inhibitor Rapamycin Inhibits Growth of Cerebral Cavernous Malformation in Adult Mice
Published in Stroke (1970) (01-11-2023)“…Cerebral cavernous malformations (CCMs) are vascular malformations that frequently cause stroke. CCMs arise due to loss of function in one of the genes that…”
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Laparoscopy assisted ventriculoperitoneal shunt placement in children
Published in Journal of pediatric surgery (01-02-2020)“…Placement of ventriculoperitoneal shunts (VPS) can be challenging in children with previous VPS, previous abdominal surgery, or complex abdominal pathology…”
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Novel Treatment of Cerebral Vasospasm Using Solitaire Stent Retriever−Assisted Angioplasty: Case Series
Published in World neurosurgery (01-03-2020)“…Endovascular procedures such as intraarterial (IA) vasodilator injection and balloon angioplasty are used to treat medically refractory cerebral vasospasm. The…”
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Penetrating Spinal Column Injuries (pSI): An Institutional Experience with 100 Consecutive Cases in an Urban Trauma Center
Published in World neurosurgery (01-06-2020)“…Gunshot wound (GSW) injuries are among the leading causes of penetrating spinal column injury (pSI). Patients with pSI often have concurrent polytrauma that…”
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Near-Infrared Optical Contrast of Skull Base Tumors During Endoscopic Endonasal Surgery
Published in Operative neurosurgery (Hagerstown, Md.) (01-07-2019)“…Abstract BACKGROUND Near-infrared (NIR) tumor contrast is achieved through the “second-window ICG” technique, which relies on passive accumulation of high…”
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400 - Traumatic Cerebrospinal Fluid Fistulas
Published in Youmans & Winn Neurological Surgery (2023)“…Traumatic head injuries with associated fractures of the skull base cause 80% of traumatic cerebrospinal fluid (CSF) leaks. Most CSF leaks may be small, may be…”
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