Search Results - "Su, Yan‐ling"

Activation of PPARA-mediated autophagy reduces Alzheimer disease-like pathology and cognitive decline in a murine model by Luo, Rongcan, Su, Ling-Yan, Li, Guiyu, Yang, Jing, Liu, Qianjin, Yang, Lu-Xiu, Zhang, Deng-Feng, Zhou, Hejiang, Xu, Min, Fan, Yu, Li, Jiali, Yao, Yong-Gang

“…Alzheimer disease (AD) is the most common neurodegenerative disease. An imbalance between the production and clearance of Aβ (amyloid beta) is considered to be…”
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Molecular Mechanism of Neuroprotective Effect of Melatonin on Morphine Addiction and Analgesic Tolerance: an Update by Su, Ling-Yan, Liu, Qianjin, Jiao, Lijin, Yao, Yong-Gang

“…Drug addiction is a global health problem and continues to place an enormous financial burden on society. This addiction is characterized by drug dependence…”
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A novel prognostic signature of seven genes for the prediction in patients with thymoma by Li, Qiang, Su, Yan-Ling, Shen, Wei-Xi

“…Purpose A thymoma is a tumor arising from the epithelium of the thymus, mostly occurring in the anterior mediastinum. The incidence of this disease is low and…”
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Melatonin alleviates morphine analgesic tolerance in mice by decreasing NLRP3 inflammasome activation by Liu, Qianjin, Su, Ling-Yan, Sun, Chunli, Jiao, Lijin, Miao, Ying, Xu, Min, Luo, Rongcan, Zuo, Xin, Zhou, Rongbin, Zheng, Ping, Xiong, Wei, Xue, Tian, Yao, Yong-Gang

“…Morphine is frequently used for pain relief, but long-term morphine therapy in patients with chronic pain results in analgesic tolerance and hyperalgesia…”
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Positive selection rather than relaxation of functional constraint drives the evolution of vision during chicken domestication by Wang, Ming-Shan, Zhang, Rong-wei, Su, Ling-Yan, Li, Yan, Peng, Min-Sheng, Liu, He-Qun, Zeng, Lin, Irwin, David M, Du, Jiu-Lin, Yao, Yong-Gang, Wu, Dong-Dong, Zhang, Ya-Ping

“…As noted by Darwin, chickens have the greatest phenotypic diversity of all birds, but an interesting evolutionary difference between domestic chickens and…”
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Does the Genetic Feature of the Chinese Tree Shrew (Tupaia belangeri chinensis) Support Its Potential as a Viable Model for Alzheimer's Disease Research? by Fan, Yu, Luo, Rongcan, Su, Ling-Yan, Xiang, Qun, Yu, Dandan, Xu, Ling, Chen, Jia-Qi, Bi, Rui, Wu, Dong-Dong, Zheng, Ping, Yao, Yong-Gang

“…Alzheimer's disease (AD) is a neurodegenerative disease with increasing incidence across the world and no cure at the present time. An ideal animal model would…”
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Out of Southern East Asia of the Brown Rat Revealed by Large-Scale Genome Sequencing by Zeng, Lin, Ming, Chen, Li, Yan, Su, Ling-Yan, Su, Yan-Hua, Otecko, Newton O, Dalecky, Ambroise, Donnellan, Stephen, Aplin, Ken, Liu, Xiao-Hui, Song, Ying, Zhang, Zhi-Bin, Esmailizadeh, Ali, Sohrabi, Saeed S, Nanaei, Hojjat Asadollahpour, Liu, He-Qun, Wang, Ming-Shan, Ag Atteynine, Solimane, Rocamora, Gérard, Brescia, Fabrice, Morand, Serge, Irwin, David M, Peng, Ming-Sheng, Yao, Yong-Gang, Li, Hai-Peng, Wu, Dong-Dong, Zhang, Ya-Ping

“…Abstract The geographic origin and migration of the brown rat (Rattus norvegicus) remain subjects of considerable debate. In this study, we sequenced whole…”
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GSNOR facilitates antiviral innate immunity by restricting TBK1 cysteine S-nitrosation by Liu, Qianjin, Gu, Tianle, Su, Ling-Yan, Jiao, Lijin, Qiao, Xinhua, Xu, Min, Xie, Ting, Yang, Lu-Xiu, Yu, Dandan, Xu, Ling, Chen, Chang, Yao, Yong-Gang

“…Innate immunity is the first line of host defense against pathogens. This process is modulated by multiple antiviral protein modifications, such as…”
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Decreased peripheral mtDNA in methamphetamine use disorder by Su, Ling-Yan, Li, Yuan, Liu, Qianjin, Jiao, Lijin, Shen, Jing, Yang, Lu-Xiu, Yuan, Ti-Fei, Yao, Yong-Gang

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Mitochondrial DNA copy number, but not haplogroup, confers a genetic susceptibility to leprosy in Han Chinese from Southwest China by Wang, Dong, Su, Ling-Yan, Zhang, A-Mei, Li, Yu-Ye, Li, Xiao-An, Chen, Ling-Ling, Long, Heng, Yao, Yong-Gang

“…Leprosy is a chronic infectious disease caused by Mycobacterium leprae, an unculturable pathogen with an exceptionally eroded genome. The high level of…”
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Cascade encapsulation of antimicrobial peptides, exosomes and antibiotics in fibrin-gel for first-aid hemostasis and infected wound healing by Su, Ling-Yan, Yao, Mengyu, Xu, Wen, Zhong, Minghua, Cao, Yu, Zhou, Hejiang

“…Wounding is one of the most common healthcare problems. Bioactive hydrogels have attracted much attention in first-aid hemostasis and wound healing due to…”
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Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor by Su, Ling-Yan, Tian, Yang, Zheng, Qiang, Cao, Yu, Yao, Mengyu, Wang, Shuangping, Xu, Wen, Xi, Chuyu, Clocchiatti, Andrea, Nie, Guangjun, Zhou, Hejiang

“…The lysosome-targeting chimera (LYTAC) approach has shown promise for the targeted degradation of secreted and membrane proteins via lysosomes. However, there…”
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Moringa oleifera Lam. leaves as new raw food material: A review of its nutritional composition, functional properties, and comprehensive application by Yang, Min, Tao, Liang, Kang, Xin-Rui, Wang, Zi-Lin, Su, Ling-Yan, Li, Ling-Fei, Gu, Fan, Zhao, Cun-Chao, Sheng, Jun, Tian, Yang

“…Moringa oleifera Lam. leaves (MOLLs) are recognised as new raw food material with various nutritional factors and phytochemical components. In recent years, a…”
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Combination of medial patellofemoral ligament reconstruction with vastus medialis advancement for chronic patellar dislocation by Wang, Fei, Kang, Hui-Jun, Chen, Bai-Cheng, Chen, Wei, Su, Yan-Ling, Zhang, Ying-Ze

“…Background The medial patellofemoral ligament （MPFL） reconstruction is popular in clinical practice for chronic patellar dislocation; however, the combination…”
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GSNOR deficiency attenuates MPTP-induced neurotoxicity and autophagy by facilitating CDK5 S-nitrosation in a mouse model of Parkinson's disease by Jiao, Lijin, Su, Ling-Yan, Liu, Qianjin, Luo, Rongcan, Qiao, Xinhua, Xie, Ting, Yang, Lu-Xiu, Chen, Chang, Yao, Yong-Gang

“…The S-nitrosoglutathione reductase (GSNOR) is a key denitrosating enzyme that regulates protein S-nitrosation, a process which has been found to be involved in…”
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Decreased mitochondrial DNA copy number in the hippocampus and peripheral blood during opiate addiction is mediated by autophagy and can be salvaged by melatonin by Feng, Yue-Mei, Jia, Yun-Fang, Su, Ling-Yan, Wang, Dong, Lv, Li, Xu, Lin, Yao, Yong-Gang

“…Drug addiction is a chronic brain disease that is a serious social problem and causes enormous financial burden. Because mitochondrial abnormalities have been…”
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Atg5- and Atg7-dependent autophagy in dopaminergic neurons regulates cellular and behavioral responses to morphine by Su, Ling-Yan, Luo, Rongcan, Liu, Qianjin, Su, Jing-Ran, Yang, Lu-Xiu, Ding, Yu-Qiang, Xu, Lin, Yao, Yong-Gang

“…The molecular basis of chronic morphine exposure remains unknown. In this study, we hypothesized that macroautophagy/autophagy of dopaminergic neurons would…”
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Extraction, structural properties, and bioactivities of Moringa (Moringa oleifera Lam.) isothiocyanates: A review by Wu, Qi, Zhou, He-Jiang, Sheng, Jun, Su, Ling-Yan, Tian, Yang

“…Moringa, a medicinal and edible plant, is rich in extremely high levels of nutrients and several active ingredients. Moringa isothiocyanates (MITC) are the key…”
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Melatonin attenuates MPTP-induced neurotoxicity via preventing CDK5-mediated autophagy and SNCA/α-synuclein aggregation by Su, Ling-Yan, Li, Hao, Lv, Li, Feng, Yue-Mei, Li, Guo-Dong, Luo, Rongcan, Zhou, He-Jiang, Lei, Xiao-Guang, Ma, Liang, Li, Jia-Li, Xu, Lin, Hu, Xin-Tian, Yao, Yong-Gang

“…Autophagy is involved in the pathogenesis of neurodegenerative diseases including Parkinson disease (PD). However, little is known about the regulation of…”
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GSNOR negatively regulates the NLRP3 inflammasome via S-nitrosation of MAPK14 by Liu, Qianjin, Jiao, Lijin, Ye, Mao-Sen, Ma, Zhiyu, Yu, Jinsong, Su, Ling-Yan, Zou, Wei-Yin, Yang, Lu-Xiu, Chen, Chang, Yao, Yong-Gang

“…Hyperactivation of the NLRP3 inflammasome has been implicated in the pathogenesis of numerous diseases. However, the precise molecular mechanisms that modulate…”
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