Search Results - "Su, Shuaikun"

Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity by Joo, Yuyoung, Xue, Yutong, Wang, Yue, McDevitt, Ross A., Sah, Nirnath, Bossi, Simone, Su, Shuaikun, Lee, Seung Kyu, Peng, Wei, Xie, Aoji, Zhang, Yongqing, Ding, Yi, Ku, Wai Lim, Ghosh, Soumita, Fishbein, Kenneth, Shen, Weiping, Spencer, Richard, Becker, Kevin, Zhao, Keji, Mattson, Mark P., van Praag, Henriette, Sharov, Alexei, Wang, Weidong

“…Topoisomerase 3β (Top3β) is the only dual-activity topoisomerase in animals that can change topology for both DNA and RNA, and facilitate transcription on DNA…”
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Topoisomerase 3b is dispensable for replication of a positive-sense RNA virus--murine coronavirus by Zhang, Tianyi, Su, Shuaikun, Altouma, Valerie, Zhu, Xingliang, Xue, Yutong, Shen, Weiping, Wilgenburg, Brian, Wang, Weidong

“…A recent study demonstrated that a DNA-RNA dual-activity topoisomerase complex, TOP3B-TDRD3, is required for normal replication of positive-sense RNA viruses,…”
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A dual-activity topoisomerase complex promotes both transcriptional activation and repression in response to starvation by Su, Shuaikun, Xue, Yutong, Lee, Seung Kyu, Zhang, Yongqing, Fan, Jinshui, De, Supriyo, Sharov, Alexei, Wang, Weidong

“…Abstract Topoisomerases are required to release topological stress generated by RNA polymerase II (RNAPII) during transcription. Here, we show that in response…”
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Resolution of R-loops by topoisomerase III-β (TOP3B) in coordination with the DEAD-box helicase DDX5 by Saha, Sourav, Yang, Xi, Huang, Shar-yin Naomi, Agama, Keli, Baechler, Simone Andrea, Sun, Yilun, Zhang, Hongliang, Saha, Liton Kumar, Su, Shuaikun, Jenkins, Lisa M., Wang, Weidong, Pommier, Yves

“…The present study demonstrates how TOP3B is involved in resolving R-loops. We observed elevated R-loops in TOP3B knockout cells (TOP3BKO), which are suppressed…”
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RNA-binding protein Nocte regulates Drosophila development by promoting translation reinitiation on mRNAs with long upstream open reading frames by Zhang, Tianyi, Xue, Yutong, Su, Shuaikun, Altouma, Valerie, Ho, Katherine, Martindale, Jennifer L, Lee, Seung-Kyu, Shen, Weiping, Park, Aaron, Zhang, Yongqing, De, Supriyo, Gorospe, Myriam, Wang, Weidong

“…Abstract RNA-binding proteins (RBPs) with intrinsically disordered regions (IDRs) are linked to multiple human disorders, but their mechanisms of action remain…”
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A dual-activity topoisomerase complex regulates mRNA translation and turnover by Su, Shuaikun, Xue, Yutong, Sharov, Alexei, Zhang, Yongqing, Lee, Seung Kyu, Martindale, Jennifer L, Li, Wen, Ku, Wai Lim, Zhao, Keji, De, Supriyo, Shen, Weiping, Sen, Payel, Gorospe, Myriam, Xu, Dongyi, Wang, Weidong

“…Abstract Topoisomerase 3β (TOP3B) and TDRD3 form a dual-activity topoisomerase complex that interacts with FMRP and can change the topology of both DNA and…”
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Tdrd3-null mice show post-transcriptional and behavioral impairments associated with neurogenesis and synaptic plasticity by Zhu, Xingliang, Joo, Yuyoung, Bossi, Simone, McDevitt, Ross A., Xie, Aoji, Wang, Yue, Xue, Yutong, Su, Shuaikun, Lee, Seung Kyu, Sah, Nirnath, Zhang, Shiliang, Ye, Rong, Pinto, Alejandro, Zhang, Yongqing, Araki, Kimi, Araki, Masatake, Morales, Marisela, Mattson, Mark P., van Praag, Henriette, Wang, Weidong

“…The Topoisomerase 3B (Top3b) - Tudor domain containing 3 (Tdrd3) protein complex is the only dual-activity topoisomerase complex that can alter both DNA and…”
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Polycomb Group Genes as the Key Regulators in Gene Silencing by Su, Shuaikun, Zhang, Min, Li, Lianyun, Wu, Min

“…The Polycomb group （PcG） genes repress gene expression mainly through chromatin modifications and regulation of chromatin structure. At present, at/east four…”
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Enhancement of functional expression of wheat peroxidase WP1 in prokaryotic system by co-transforming with hemA and hemL of Esherichia coli by Zhang, Chao, Shan, Liwei, Su, Shuaikun, Nan, Yanni, Guo, Zhongyu, Fan, Sanhong

“…Wheat grain peroxidase 1 (WP1) belonged to class III plant peroxidase with cofactor heme, which not only has antifungal activity, but also influences the…”
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