Search Results - "Su, Ming‐Wei"

Systematic druggable genome-wide Mendelian randomisation identifies therapeutic targets for Alzheimer's disease by Su, Wei-Ming, Gu, Xiao-Jing, Dou, Meng, Duan, Qing-Qing, Jiang, Zheng, Yin, Kang-Fu, Cai, Wei-Chen, Cao, Bei, Wang, Yi, Chen, Yong-Ping

“…Alzheimer's disease (AD) is the leading cause of dementia. Currently, there are no effective disease-modifying treatments for AD. Mendelian randomisation (MR)…”
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Investigating obesity‐related risk factors for childhood asthma by Chen, Yang‐Ching, Su, Ming‐Wei, Brumpton, Ben M., Lee, Yungling L., Kalayci, Ömer

“…Background We tested the hypothesis that multiple obesity‐related risk factors (obesity, physical activity, cardiopulmonary physical fitness, sleep‐disorder…”
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Genetic profiles of 103,106 individuals in the Taiwan Biobank provide insights into the health and history of Han Chinese by Wei, Chun-Yu, Yang, Jenn-Hwai, Yeh, Erh-Chan, Tsai, Ming-Fang, Kao, Hsiao-Jung, Lo, Chen-Zen, Chang, Lung-Pao, Lin, Wan-Jia, Hsieh, Feng-Jen, Belsare, Saurabh, Bhaskar, Anand, Su, Ming-Wei, Lee, Te-Chang, Lin, Yi-Ling, Liu, Fu-Tong, Shen, Chen-Yang, Li, Ling-Hui, Chen, Chien-Hsiun, Wall, Jeffrey D., Wu, Jer-Yuarn, Kwok, Pui-Yan

“…Personalized medical care focuses on prediction of disease risk and response to medications. To build the risk models, access to both large-scale genomic…”
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Genetic factors for survival in amyotrophic lateral sclerosis: an integrated approach combining a systematic review, pairwise and network meta-analysis by Su, Wei-Ming, Gu, Xiao-Jing, Duan, Qing-Qing, Jiang, Zheng, Gao, Xia, Shang, Hui-Fang, Chen, Yong-Ping

“…The time of survival in patients with amyotrophic lateral sclerosis (ALS) varies greatly, and the genetic factors that contribute to the survival of ALS are…”
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Systematic druggable genome‐wide Mendelian randomization identifies therapeutic targets for sarcopenia by Yin, Kang‐Fu, Chen, Ting, Gu, Xiao‐Jing, Su, Wei‐Ming, Jiang, Zheng, Lu, Si‐Jia, Cao, Bei, Chi, Li‐Yi, Gao, Xia, Chen, Yong‐Ping

“…Background There are no effective pharmacological treatments for sarcopenia. We aim to identify potential therapeutic targets for sarcopenia by integrating…”
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TBK1, a prioritized drug repurposing target for amyotrophic lateral sclerosis: evidence from druggable genome Mendelian randomization and pharmacological verification in vitro by Duan, Qing-Qing, Wang, Han, Su, Wei-Ming, Gu, Xiao-Jing, Shen, Xiao-Fei, Jiang, Zheng, Ren, Yan-Ling, Cao, Bei, Li, Guo-Bo, Wang, Yi, Chen, Yong-Ping

“…There is a lack of effective therapeutic strategies for amyotrophic lateral sclerosis (ALS); therefore, drug repurposing might provide a rapid approach to meet…”
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The mutation spectrum of Parkinson‐disease‐related genes in early‐onset Parkinson's disease in ethnic Chinese by Chen, Yong‐Ping, Yu, Shi‐Hui, Zhang, Guo‐Hui, Hou, Yan‐Bing, Gu, Xiao‐Jing, Ou, Ru‐Wei, Shen, Ying, Song, Wei, Chen, Xue‐Ping, Zhao, Bi, Cao, Bei, Zhang, Ling‐Yu, Sun, Ming‐Ming, Liu, Fei‐Fei, Wei, Qian‐Qian, Liu, Kun‐Cheng, Lin, Jun‐Yu, Yang, Tian‐Mi, Yang, Jing, Wu, Ying, Jiang, Zheng, Liu, Jiao, Cheng, Yang‐Fan, Xiao, Yi, Su, Wei‐Ming, Feng, Fei, Cai, Ying‐Ying, Li, Shi‐Rong, Hu, Tao, Yuan, Xiao‐Qin, Zhou, Qing‐Qing, Shao, Na, Ma, Sha, Shang, Hui‐Fang

“…Background and purpose Recent genetic progress has shown many causative/risk genes linked to Parkinson's disease (PD), mainly in patients of European ancestry…”
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The Causal Relationship of Circulating Triglyceride and Glycated Hemoglobin: A Mendelian Randomization Study by Hsiung, Chia-Ni, Chang, Yi-Cheng, Lin, Chien-Wei, Chang, Chia-Wei, Chou, Wen-Cheng, Chu, Hou-Wei, Su, Ming-Wei, Wu, Pei-Ei, Shen, Chen-Yang

“…Abstract Context The association between circulating triglyceride (TG) and glycated hemoglobin A1c (HbA1c), a biomarker for type 2 diabetes, has been widely…”
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Predictors of survival in patients with amyotrophic lateral sclerosis: A large meta-analysis by Su, Wei-Ming, Cheng, Yang-Fan, Jiang, Zheng, Duan, Qing-Qing, Yang, Tian-Mi, Shang, Hui-Fang, Chen, Yong-Ping

“…The survival time of amyotrophic lateral sclerosis (ALS) is greatly variable and protective or risk effects of the potential survival predictors are…”
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Blood multiomics reveal insights into population clusters with low prevalence of diabetes, dyslipidemia and hypertension by Su, Ming-Wei, Chang, Chung-Ke, Lin, Chien-Wei, Ling, Shiu-Jie, Hsiung, Chia-Ni, Chu, Hou-Wei, Wu, Pei-Ei, Shen, Chen-Yang

“…Diabetes, dyslipidemia and hypertension are important metabolic diseases that impose a great burden on many populations worldwide. However, certain population…”
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Estimation of the Core Losses of Induction Machines Based on the Corrected Epstein Test Method by Su, Wei-Ming, Mao, Shang-Hsun, Wang, Pei-Jen

“…A revised method based on the standard Epstein test is proposed to improve the accuracy of the estimation of the core losses of induction machines (IMs). Since…”
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Risk factors of amyotrophic lateral sclerosis: a global meta-summary by Duan, Qing-Qing, Jiang, Zheng, Su, Wei-Ming, Gu, Xiao-Jing, Wang, Han, Cheng, Yang-Fan, Cao, Bei, Gao, Xia, Wang, Yi, Chen, Yong-Ping

“…The etiology of amyotrophic lateral sclerosis (ALS) remains largely unknown. This study aimed to summarize the relationship between ALS and its genetic and…”
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CEACAM3 decreases asthma exacerbations and modulates respiratory syncytial virus latent infection in children by Tsai, Ching-Hui, Wu, Ann Chen, Chiang, Bor-Luen, Yang, Yao-Hsu, Hung, Shih-Pin, Su, Ming-Wei, Chang, Ya-Jen, Lee, Yungling L

“…Respiratory syncytial virus (RSV) is associated with childhood asthma. Nevertheless, not all children exposed to RSV develop asthma symptoms, possibly because…”
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Taiwan Biobank: A rich biomedical research database of the Taiwanese population by Feng, Yen-Chen Anne, Chen, Chia-Yen, Chen, Tzu-Ting, Kuo, Po-Hsiu, Hsu, Yi-Hsiang, Yang, Hwai-I, Chen, Wei J., Su, Ming-Wei, Chu, Hou-Wei, Shen, Chen-Yang, Ge, Tian, Huang, Hailiang, Lin, Yen-Feng

“…The Taiwan Biobank (TWB) is an ongoing prospective study of >150,000 individuals aged 20–70 in Taiwan. A comprehensive list of phenotypes was collected for…”
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Sex-specific interactive effect of melamine and DEHP on a marker of early kidney damage in Taiwanese adults: A national population-based study from the Taiwan Biobank by Li, Sih-Syuan, Chen, Jia-Jen, Su, Ming-Wei, Lin, Chien-Wei, Chen, Chu-Chih, Wang, Yin-Han, Liu, Chia-Chu, Tsai, Yi-Chun, Hsieh, Tusty-Jiuan, Wu, Ming-Tsang, Wu, Chia-Fang

“…Taiwan had the high incidence of chronic kidney disease (CKD) worldwide. Our objective was to examine associations between daily exposure of phthalates and…”
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A Process-Aware Memory Compact-Device Model Using Long-Short Term Memory by Lin, Albert S., Pratik, Sparsh, Ota, Jun, Rawat, Tejender Singh, Huang, Tzu-Hsiang, Hsu, Chun-Ling, Su, Wei-Ming, Tseng, Tseung-Yuen

“…With the immense increase in the processing data during the scaling down of semiconductor devices by Moore's Law, it is in urgent need to use data analytics to…”
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Gene-gene and gene-environmental interactions of childhood asthma: a multifactor dimension reduction approach by Su, Ming-Wei, Tung, Kuan-Yen, Liang, Pi-Hui, Tsai, Ching-Hui, Kuo, Nai-Wei, Lee, Yungling Leo

“…The importance of gene-gene and gene-environment interactions on asthma is well documented in literature, but a systematic analysis on the interaction between…”
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The role of interleukin-33 in patients with mild cognitive impairment and Alzheimer's disease by Liang, Chih-Sung, Su, Kuan-Pin, Tsai, Chia-Lin, Lee, Jiunn-Tay, Chu, Che-Sheng, Yeh, Ta-Chuan, Su, Ming-Wei, Lin, Guan-Yu, Lin, Yu-Kai, Chu, Hsuan-Te, Tsai, Chia-Kuang, Yang, Fu-Chi

“…The neuroprotective role of interleukin (IL)-33 is supported by numerous preclinical studies, but it remains uninvestigated in clinical studies of Alzheimer's…”
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Production of a human iPSC line from an early-onset Parkinson’s disease patient with a novel CHCHD2 gene truncated mutation by Jiang, Zheng, Gu, Xiao-Jing, Su, Wei-Ming, Duan, Qing-Qing, Lin, Jun-Yu, Cao, Bei, Shang, Hui-Fang, Chen, Yong-Ping

“…CHCHD2 mutations have been reported to cause Parkinson’s disease (PD) by a loss of function in mitochondria. Most reported mutations, however, were missense,…”
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Protective effect of antihypertensive drugs on the risk of Parkinson's disease lacks causal evidence from mendelian randomization by Jiang, Zheng, Gu, Xiao-Jing, Su, Wei-Ming, Duan, Qing-Qing, Ren, Yan-Lin, Li, Ju-Rong, Chi, Li-Yi, Wang, Yi, Cao, Bei, Chen, Yong-Ping

“…Evidence from observational studies concerning the causal role of blood pressure (BP) and antihypertensive medications (AHM) on Parkinson's disease (PD)…”
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