Search Results - "Su, C W"
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Cabozantinib in hepatocellular carcinoma: results of a phase 2 placebo-controlled randomized discontinuation study
Published in Annals of oncology (01-03-2017)“…Cabozantinib, an orally bioavailable inhibitor of tyrosine kinases including MET, AXL, and VEGF receptors, was assessed in patients with hepatocellular…”
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Osimertinib versus platinum–pemetrexed for patients with EGFR T790M advanced NSCLC and progression on a prior EGFR-tyrosine kinase inhibitor: AURA3 overall survival analysis
Published in Annals of oncology (01-11-2020)“…In AURA3 (NCT02151981), osimertinib, a third-generation epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitor (TKI), significantly prolonged…”
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Hepatitis C virus infection: a risk factor for Parkinson's disease
Published in Journal of viral hepatitis (01-10-2015)“…Summary Recent studies found that hepatitis C virus (HCV) may invade the central nervous system, and both HCV and Parkinson's disease (PD) have in common the…”
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Translational insights and overall survival in the U31402-A-U102 study of patritumab deruxtecan (HER3-DXd) in EGFR-mutated NSCLC
Published in Annals of oncology (01-05-2024)“…Human epidermal growth factor receptor 3 (HER3) is broadly expressed in non-small-cell lung cancer (NSCLC) and is the target of patritumab deruxtecan…”
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Sp1 expression regulates lung tumor progression
Published in Oncogene (30-08-2012)“…The role of specificity protein 1 (Sp1) in controlling gene expression in lung tumor development and metastasis is not well understood. In this study, we…”
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Letter: the role of direct‐acting anti‐virals in determining the risk of hepatocellular carcinoma development in patients with hepatitis C virus‐induced cirrhosis
Published in Alimentary pharmacology & therapeutics (01-04-2018)“…Linked content This article is linked to Mettke et al and Mettke and Wedemeyer papers. To view these articles visit https://doi.org/10.1111/apt.14427 and…”
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Vinflunine–gemcitabine versus vinflunine–carboplatin as first-line chemotherapy in cisplatin-unfit patients with advanced urothelial carcinoma: results of an international randomized phase II trial (JASINT1)
Published in Annals of oncology (01-03-2016)“…There is no standard first-line chemotherapy for advanced urothelial carcinoma (aUC) in cisplatin-ineligible (cisplatin-unfit) patients. The study assessed the…”
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Flexible low-temperature polycrystalline silicon thin-film transistors
Published in Materials today advances (01-03-2020)“…In today's society, displays are indispensable for digital interaction and personal contact. Therefore, the development of displays is an urgent need for the…”
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Autocrine IL-6-induced Stat3 activation contributes to the pathogenesis of lung adenocarcinoma and malignant pleural effusion
Published in Oncogene (20-07-2006)“…Malignant pleural effusion (MPE) is a poor prognostic sign for patients with non-small-cell lung cancer (NSCLC). The generation of MPE is largely regulated by…”
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Updated thresholds for serum alanine aminotransferase level in a large-scale population study composed of 34 346 subjects
Published in Alimentary pharmacology & therapeutics (01-09-2012)“…Summary Background The sensitivity of current upper limit of normal (ULN) of serum alanine aminotransferase (ALT) levels for detecting chronic liver disease…”
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Oncoprotein ZNF322A transcriptionally deregulates alpha-adducin, cyclin D1 and p53 to promote tumor growth and metastasis in lung cancer
Published in Oncogene (05-05-2016)“…ZNF322A encoding a classical Cys2His2 zinc finger transcription factor was previously revealed as a potential oncogene in lung cancer patients. However, the…”
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Randomized phase III study of docetaxel plus bavituximab in previously treated advanced non-squamous non-small-cell lung cancer
Published in Annals of oncology (01-07-2018)“…Bavituximab is a monoclonal antibody that targets phosphatidylserine in the presence of β2 glycoprotein 1 (β2GP1) to exert an antitumor immune response. This…”
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EGF-mediated inhibition of ubiquitin-specific peptidase 24 expression has a crucial role in tumorigenesis
Published in Oncogene (25-05-2017)“…In this study, several cancer-related proteins (Bax, p300, E2F4 and securin) have been proven to be substrates of ubiquitin-specific peptidase 24 (USP24), and…”
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MMP7-mediated cleavage of nucleolin at Asp255 induces MMP9 expression to promote tumor malignancy
Published in Oncogene (12-02-2015)“…Nucleolin (NCL) participates in DNA transcription, ribosomal biogenesis and the regulation of RNA stability. However, the contribution of NCL to tumor…”
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Randomised clinical trial: comparison of two everolimus dosing schedules in patients with advanced hepatocellular carcinoma
Published in Alimentary pharmacology & therapeutics (01-01-2013)“…Summary Background Deregulation of mammalian target of rapamycin (mTOR) signalling is common in human hepatocellular carcinoma (HCC). Aim To determine the…”
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The challenge and future of rocky desertification control in karst areas in southwest China
Published in Solid earth (Göttingen) (01-01-2016)“…Karst rocky desertification occurs after vegetation deteriorates as a result of intensive land use, which leads to severe water loss and soil erosion and…”
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Cancer risk in patients with pyogenic liver abscess: a nationwide cohort study
Published in Alimentary pharmacology & therapeutics (01-09-2012)“…Summary Background There has been no large‐scale population‐based study on the relationship between pyogenic liver abscesses (PLA) and subsequent cancer risk…”
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Serum alpha-fetoprotein response can predict prognosis in hepatocellular carcinoma patients undergoing radiofrequency ablation therapy
Published in Clinical radiology (01-05-2012)“…Aims To evaluate the clinical inference of serum alpha-fetoprotein (AFP) response in hepatocellular carcinoma (HCC) patients undergoing percutaneous…”
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