Search Results - "Stytsenko, T S"
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1
Novel immobilized biocatalyst for microbiological synthesis of pharmaceutical steroids
Published in Applied biochemistry and microbiology (01-09-2015)“…The steroid-transforming activity of free and immobilized cells of Pimelobacter simplex VKPM Ac-1632 entrapped in an operationally stable macroporous…”
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2
Conversion of soybean sterols into 3,17-diketosteroids using actinobacteria Mycobacterium neoaurum, Pimelobacter simplex, and Rhodococcus erythropolis
Published in Applied biochemistry and microbiology (01-05-2011)“…Soybean sterols were converted into androst-4-ene-3,17-dione (AD) and 9α-hydroxyandrost-4-ene-3,17-dione (9-OH-AD) using three actinobacterium strains. The…”
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3
Effect of the steroid molecule structure on the direction of its hydroxylation by the fungus Curvularia lunata
Published in Applied biochemistry and microbiology (01-07-2013)“…The main and side products of hydroxylation by the C. lunata VKPM F-981 mycelium of fourteen Δ₄-3-ketosteroids of the estrane, androstane, and pregnane series…”
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4
Synthesis of 3β-methyl ether of dehydroepiandrosterone by biotransformation of 3β-methyl ether of cholesterol with cells of mycobacteria Mycobacterium sp
Published in Russian chemical bulletin (01-12-2019)“…3p-Methyl ether of dehydroepiandrosterone was obtained by microbiological transformation of 3ß-methyl ether of cholesterol with Mycobacterium sp…”
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5
Study of biotransformation of cholesterol 3β-methyl ether by mycobacteria Mycobacterium sp
Published in Russian chemical bulletin (01-03-2021)“…The influence of exogenous factors on the selectivity of biotransformation of cholesterol 3β-methyl ether by Mycobacterium sp. was studied. The main product of…”
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6
Preparation of Plant and Animal Sterol Ethers and Esters as Key Intermediates for the Synthesis of Dehydroepiandrosterone
Published in Pharmaceutical chemistry journal (01-02-2020)“…Series of cholesterol and β-sitosterol ethers and esters were obtained and could be used for subsequent enzymatic cleavage of the steroid C-17 side chain to…”
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7
Efficient Synthesis of 21-Acetoxypregna-1,4,9,16-Tetraene-3,20-Dione, a Key Intermediate in the Synthesis of Highly Active Fluorinated Corticosteroids from 9[alpha]-Hydroxyandrostenedione
Published in Pharmaceutical chemistry journal (01-12-2018)“…An efficient synthesis of 21-acetoxypregna-1,4,9(11),16-tetraene-3,20-dione, a key intermediate in the synthesis of highly active fluorinated corticosteroids…”
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8
A search for microscopic fungi with directed hydroxylase activity for the synthesis of steroid drugs
Published in Applied biochemistry and microbiology (01-05-2016)“…The hydroxylase activities of new strains such as Curvularia lunata , C. geniculata , C. eragrostidis , C. prasadii , Ulocladium botrytis , Alternaria tenuis ,…”
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9
Optimization of the 9α-hydroxylation of steroid substrates using an original culture of Rhodococcus erythropolis
Published in Regulatory mechanisms in biosystems (16-07-2018)“…To obtain inoculation material (cultivation stage 1), the biomass of Rhodococcus erythropolis VKPM AC-1740 was transferred from agar slants into 750 ml conic…”
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10
Conversion of Androstenedione and Androstadienedione by Sterol-Degrading Bacteria
Published in Applied biochemistry and microbiology (01-09-2004)“…The composition of steroid metabolites formed during the conversion of androstenedione and androstadienedione, products of the degradation of sterol side…”
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11
Conversion of 17α-methyltestosterone to methandrostenolone by the bacterium pimelobacter simplex VKPM Ac-1632 with the presence of cyclodextrins
Published in Applied biochemistry and microbiology (01-11-2008)“…Conditions of conversion of 17α-methyltestosterone to methandrostenolone with the presence of modified β-cyclodextrins (methylcyclodextrin,…”
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12
7α-Hydroxylation of steroid 5-olefins by mold fungi
Published in Applied biochemistry and microbiology (2010)“…Hydroxylation activity of the mold fungi belonging to the orders Dothideales, Hypocreales, and Mucorales towards Δ⁵-3β-hydroxysteroids was studied. The fungi…”
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13
Identification of a New Steroid-Transforming Strain of Mycobacteria as Mycobacterium neoaurum
Published in Applied biochemistry and microbiology (01-03-2003)“…The ability to utilize sterols as a sole source of carbon was studied in 80 strains and consortia of hydrocarbon-oxidizing bacteria. One of the strains, which…”
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14
Conversion of phytosterols into androstenedione by Mycobacterium neoaurum
Published in Applied biochemistry and microbiology (2008)“…Optimum conditions for transformation of phytosterols by Mycobacterium neoaurum, required for selective cleavage of the lateral chain into androstenedione,…”
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15
introduction of the 9α-hydroxy group into androst-4-en-3,17-dione using a new actinobacterium strain
Published in Applied biochemistry and microbiology (01-07-2009)“…A 9α-hydrolase activity of a new actinobacterium strain identified as Rhodococcus erythropolis based on the analysis of a 16S rRNA gene sequence (1417…”
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16
Transformation of Δ4-3-ketosteroids by free and immobilized cells of Rhodococcus erythropolis actinobacterium
Published in Applied biochemistry and microbiology (2011)“…ABSTARCT: 9α-Hydroxy derivatives were prepared from 11 steroids of androstane and pregnane series using Rhodococcus erythropolis VKPM Ac-1740 culture with…”
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17
Conversion of phytosterols into androstenedione by Mycobacterium neoaurum
Published in Applied biochemistry and microbiology (01-01-2008)“…Optimum conditions for transformation of phytosterols by Mycobacterium neoaurum, required for selective cleavage of the lateral chain into androstenedione,…”
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18
Preparation of androsta-1,4-diene-3,17-dione from sterols using Mycobacterium neoaurum VKPM Ac-1656 strain
Published in Russian journal of bioorganic chemistry (01-05-2007)“…A product of microbiological cleavage of the sterols side chain, androsta-1,4-diene-3,17-dione, is toxic for bacteria, in particular, actinobacteria of the…”
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19
Conversion of 17 alpha-methyltestosterone to methandrostenolone by the bacterium Pimelobacter simplex VKPM Ac-1632 with the presence of cyclodextrins
Published in Prikladnaja biohimija i mikrobiologija (01-11-2008)“…Conditions of conversion of 17 alpha-methyltestosterone to methandrostenolone with the presence of modified beta-cyclodextrins (methylcyclodextrin,…”
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20
Studies of synthesis routes for biologically active 14α-hydroxylated steroids
Published in Pharmaceutical chemistry journal (2009)“…The conditions for preparing 14α-hydroxyandrostenedione - an intermediate in the synthesis of highly active gestagens - using the fungus Curvularia lunata CBE…”
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