Search Results - "Stutzmann, J.M."

The metabotropic glutamate receptor subtype 5 antagonist MPEP and the Na+ channel blocker riluzole show different neuroprotective profiles in reversing behavioral deficits induced by excitotoxic prefrontal cortex lesions by Risterucci, C., Coccurello, R., Banasr, M., Stutzmann, J.M., Amalric, M., Nieoullon, A.

“…Overactivation of excitatory amino acid receptors has been involved in several neurodegenerative diseases. The present study aims at investigating the…”
Get full text

Unraveling substantia nigra sequential gene expression in a progressive MPTP-lesioned macaque model of Parkinson's disease by Bassilana, F., Mace, N., Li, Q., Stutzmann, J.M., Gross, C.E., Pradier, L., Benavides, J., Ménager, J., Bezard, E.

“…Taking advantage of a progressive nonhuman primate model mimicking Parkinson's disease (PD) evolution, we monitored transcriptional fluctuations in the…”
Get full text

Effects of opiate-like peptides, morphine, and naloxone in the photosensitive baboon, Papio papio by Meldrum, B S, Menini, C, Stutzmann, J M, Naquet, R

“…The effects of intracerebroventricular (i.c.v.) or systemic injections of Met- or Leu-enkephalin, beta-endorphin, FK 33.824 (D-Ala2, MePhe4,…”
Get more information

Riluzole promotes survival of rat motoneurons in vitro by stimulating trophic activity produced by spinal astrocyte monolayers by Peluffo, H, Estevez, A, Barbeito, L, Stutzmann, J.M

“…In the present study we have assessed whether riluzole stimulates the production of trophic activities for motoneurons by spinal astrocyte cultures. Astrocyte…”
Get full text

Effect of riluzole on quinolinate-induced neuronal damage in rats: comparison with blockers of glutamatergic neurotransmission by Mary, V., Wahl, F., Stutzmann, J.M.

“…Intrastriatal injection of quinolinate, an N-methyl- d-aspartate (NMDA) agonist, induces a local neuronal lesion, and provides an excitotoxic model of…”
Get full text

Effects of riluzole on the electrophysiological activity of pallidal neurons in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-treated monkey by Boraud, Th, Bezard, E, Stutzmann, J.M, Bioulac, B, Gross, C.E

“…The effect of riluzole administration, an antiglutamatergic compound, on the electrophysiological activity of the pallidal complex of…”
Get full text

Proconvulsant, convulsant and other actions of the D- and L-stereoisomers of allylglycine in the photosensitive baboon, Papio papio by Meldrum, B S, Menini, C, Naquet, R, Laurent, H, Stutzmann, J M

“…The effects of the intravenous or intracerebroventricular injection of the stereoisomers, and the racemic mixture, of allylglycine (2-amino-pent-4-enoic acid)…”
Get more information

Are 5-HT2 antagonists endowed with anxiolytic properties in rodents? by Stutzmann, J M, Eon, B, Darche, F, Lucas, M, Rataud, J, Piot, O, Blanchard, J C, Laduron, P M

“…The precise role of serotonin (5-HT) in anxiety remains unclear. We report here on the effects of RP 62203, a new 5-HT2 antagonist, and ritanserin in different…”
Get more information

Cyclopyrrolones, unlike some benzodiazepines, do not induce physical dependence in mice by Piot, O, Betschart, J, Stutzmann, J M, Blanchard, J C

“…In a model of physical dependence in mice, treatment with cyclopyrrolones such as zopiclone and suriclone (from 4 to 400 mg/kg/day), did not modify the…”
Get more information

Riluzole, a glutamate antagonist, enhances slow wave and REM sleep in rats by Stutzmann, J M, Lucas, M, Blanchard, J C, Laduron, P M

“…Riluzole is a drug that interferes with glutamate neurotransmitters. We studied the sleep pattern of rats treated orally with riluzole at doses ranging from…”
Get more information

Pharmacological studies on zopiclone by Julou, L, Bardone, M C, Blanchard, J C, Garret, C, Stutzmann, J M

“…Zopiclone (RP 27 267) is an hypnotic with a chemical structure different from that of the benzodiazepines (BZD) or barbiturates. Studies of zopiclone in…”
Get more information

Neuroprotection against ischaemia and Improvement of sleep quality with rlluzole a novel antiglutamate by Blanchard, J.C., Malgouris, C., Rataud, J., Stutzmann, J.M., Laduron, P.M.

Get full text

Paroxysmal visual evoked potentials (PVEPs) in Papio papio. I. Morphological and topographical characteristics. Comparison with paroxysmal discharges by Menini, C, Stutzmann, J M, Laurent, H, Naquet, R

Get more information

Paroxysmal visual evoked potentials (PVEPs) in Papio papio. II. Evidence for a facilitatory effect of intermittent photic stimulation by Stutzman, J M, Laurent, H, Valin, A, Menini, C

Get more information

Cortical unit activity during intermittent photic stimulation in Papio papio. Relationship with paroxysmal fronto-rolandic activity by Ménini, C, Silva-Comte, C, Stutzmann, J M, Dimov, S

“…Extracellular records have been made in the fronto-rolandic (FR), parietal and occipital cortical areas in Papio papio injected with allylglycine and paralysed…”
Get more information

Cerebral and extracerebral blood volume in generalized seizures in the baboon Papio papio by Ancri, D, Naquet, R, Menini, C, Meldrum, B, Stutzmann, J M, Basset, J Y

“…Relative variations of the cerebral and extracerebral blood volume (CBV) were measured continuously by a novel atraumatic method in baboons to explore the…”
Get more information