Search Results - "Stutte, Susanne"
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High-fat diet-derived free fatty acids impair the intestinal immune system and increase sensitivity to intestinal epithelial damage
Published in Biochemical and biophysical research communications (19-02-2020)“…In Japan and other Asian countries, increased fat uptake induced by a westernized diet is thought to be associated with an increased incidence of inflammatory…”
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High-Fat Diet Rapidly Modifies Trafficking, Phenotype, and Function of Plasmacytoid Dendritic Cells in Adipose Tissue
Published in The Journal of immunology (1950) (15-03-2022)“…Plasmacytoid dendritic cells (pDCs) display an increased abundance in visceral adipose tissue (VAT) of humans with obesity. In the current study, we set out to…”
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Type I interferon mediated induction of somatostatin leads to suppression of ghrelin and appetite thereby promoting viral immunity in mice
Published in Brain, behavior, and immunity (01-07-2021)“…[Display omitted] •Infections are associated with behavioral characteristics, such loss of appetite (anorexia) that can result in weight loss and that…”
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Requirement of CCL17 for CCR7- and CXCR4-dependent migration of cutaneous dendritic cells
Published in Proceedings of the National Academy of Sciences - PNAS (11-05-2010)“…Chemokines are known to regulate the steady-state and inflammatory migration of cutaneous dendritic cells (DCs). The β-chemokine CCL17, a ligand of CCR4, is…”
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Expression of the Phosphatase Ppef2 Controls Survival and Function of CD8 + Dendritic Cells
Published in Frontiers in immunology (12-02-2019)“…Apoptotic cell death of Dendritic cells (DCs) is critical for immune homeostasis. Although intrinsic mechanisms controlling DC death have not been fully…”
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CCL22 controls immunity by promoting regulatory T cell communication with dendritic cells in lymph nodes
Published in The Journal of experimental medicine (06-05-2019)“…Chemokines have crucial roles in organ development and orchestration of leukocyte migration. The chemokine CCL22 is expressed constitutively at high levels in…”
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Spinal cord injury-induced immunodeficiency is mediated by a sympathetic-neuroendocrine adrenal reflex
Published in Nature neuroscience (01-11-2017)“…Spinal cord injury causes life-threatening infections. The authors report that this is partially mediated by a maladaptive neuroendocrine reflex, extending…”
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Antigen Availability Determines CD8+ T Cell-Dendritic Cell Interaction Kinetics and Memory Fate Decisions
Published in Immunity (Cambridge, Mass.) (19-09-2013)“…T cells are activated by antigen (Ag)-bearing dendritic cells (DCs) in lymph nodes in three phases. The duration of the initial phase of transient, serial DC-T…”
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Plasmacytoid dendritic cells control homeostasis of megakaryopoiesis
Published in Nature (London) (18-07-2024)“…Platelet homeostasis is essential for vascular integrity and immune defence 1 , 2 . Although the process of platelet formation by fragmenting megakaryocytes…”
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Cell division cycle 42 (Cdc42) regulates functions of plasmacytoid dendritic cells
Published in The Journal of immunology (1950) (01-05-2016)“…Abstract Cell division cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal functions in actin organization, cell migration…”
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Intravital two-photon microscopy of immune cells in visceral adipose tissue (173.38)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract Obesity causes systemic low-grade inflammation predisposing to metabolic disorders including insulin resistance, diabetes, dyslipidemia and…”
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Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells
Published in The Journal of cell biology (09-11-2015)“…Cell division cycle 42 (Cdc42) is a member of the Rho guanosine triphosphatase family and has pivotal functions in actin organization, cell migration, and…”
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CD24a Expression Levels Discriminate Langerhans Cells from Dermal Dendritic Cells in Murine Skin and Lymph Nodes
Published in Journal of investigative dermatology (01-06-2008)“…Langerhans cells (LCs) and dermal dendritic cells (dDCs) are the professional antigen-presenting cells of the skin. Recently, their immunogenic versus…”
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Cdc42-dependent actin dynamics controls maturation and secretory activity of dendritic cells
Published in The Journal of experimental medicine (16-11-2015)Get full text
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A Distinct Population of Lipid Sensing iNKT Cells are Enriched in Fat and Protect Against Diet-Induced Obesity and Insulin Resistance (176.26)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract Immunometabolic interactions regulate adipose tissue inflammation in obesity and subsequent development of insulin resistance. We have shown that…”
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Antigen availability is a critical determinant of in vivo CD8+ T cell-dendritic cell interaction kinetics and initiates effector/memory fate decisions (110.21)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract Naïve CD8+ T cells are activated through interactions with antigen (Ag) bearing dendritic cells (DCs) in lymph nodes (LNs). Multiphoton intravital…”
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Transcriptional signatures of immune cells in aryl hydrocarbon receptor (AHR)-proficient and AHR-deficient mice
Published in Biological chemistry (01-09-2006)“…The ligand-activated aryl hydrocarbon receptor (AHR) is known to modulate many genes in a highly cell-specific manner, either directly or indirectly via…”
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