Search Results - "Sturzl, M"
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Expression of K13/v-FLIP gene of Human herpesvirus 8 and apoptosis in Kaposi's sarcoma spindle cells
Published in JNCI : Journal of the National Cancer Institute (20-10-1999)“…Human herpesvirus 8 (HHV8) infection is associated with all forms of Kaposi's sarcoma (KS). The HHV8 genome locus ORFK13-72-73 (ORF = open reading frame)…”
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Kaposi’s sarcoma: a result of the interplay among inflammatory cytokines, angiogenic factors and viral agents
Published in Cytokine & growth factor reviews (01-03-1998)“…Kaposi’s sarcoma (KS) is an angioproliferative disease occurring in 4 clinic-epidemiologic forms. Although the AIDS-associated KS (AIDS-KS) is the most…”
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3
MDM-2 Oncoprotein Overexpression, p53 Gene Mutation, and VEGF Up-Regulation in Angiosarcomas
Published in The American journal of pathology (01-11-1998)“…The endothelium is one of the largest cellular compartments of the human body and has a high proliferative potential. However, angiosarcomas are among the…”
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Cytokine-mediated growth promotion of Kaposi's sarcoma and primary effusion lymphoma
Published in Seminars in cancer biology (01-10-2000)“…Kaposi's sarcoma (KS) is an angioproliferative disease particularly frequent and aggressive in patients with AIDS but occurring also in post-transplant…”
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A role for MALT1 activity in Kaposi’s sarcoma-associated herpes virus latency and growth of primary effusion lymphoma
Published in Leukemia (01-03-2017)“…Primary effusion lymphoma (PEL) is an incurable malignancy that develops in immunodeficient patients as a consequence of latent infection of B-cells with…”
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Reactivation and Persistence of Human Herpesvirus-8 Infection in B Cells and Monocytes by Th-1 Cytokines Increased in Kaposi's Sarcoma
Published in Blood (15-06-1999)“…Patients with Kaposi's sarcoma (KS) have a human herpesvirus-8 (HHV-8) load higher than patients without KS and present a CD8+ T-cell activation with…”
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Human herpesvirus-8 and Kaposi's sarcoma: Relationship with the multistep concept of tumorigenesis
Published in Advances in Cancer Research (2001)“…Kaposi's sarcoma (KS) develops through discrete inflammatory-angiogenic stages of polyclonal nature (early-stage lesions) to monomorphic nodules of…”
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Book Chapter Journal Article -
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Structural proteins of Kaposi’s sarcoma-associated herpesvirus antagonize p53-mediated apoptosis
Published in Oncogene (29-01-2015)“…The tumor suppressor p53 is a central regulatory molecule of apoptosis and is commonly mutated in tumors. Kaposi’s sarcoma-associated herpesvirus…”
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Journal Article -
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Reactivation and role of HHV-8 in Kaposi's sarcoma initiation
Published in Advances in Cancer Research (2001)“…Kaposi's sarcoma (KS) is an angioproliferative disease occurring in several clinical-epidemio-logic forms but all associated with infection by the human…”
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Book Chapter Journal Article -
10
Molecular staging of lymph node-negative colon carcinomas by one-step nucleic acid amplification (OSNA) results in upstaging of a quarter of patients in a prospective, European, multicentre study
Published in British journal of cancer (13-05-2014)“…Background: Current histopathological staging procedures in colon carcinomas depend on midline division of the lymph nodes with one section of haematoxylin &…”
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Journal Article -
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IFN-gamma induces endothelial cells to proliferate and to invade the extracellular matrix in response to the HIV-1 Tat protein: implications for AIDS-Kaposi's sarcoma pathogenesis
Published in The Journal of immunology (1950) (15-01-1999)“…Previous studies indicated that the Tat protein of HIV functions as a progression factor in Kaposi's sarcoma (KS), an angioproliferative disease common and…”
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Kaposi's sarcoma-associated herpesvirus serology in Europe and Uganda : Multicentre study with multiple and novel assays
Published in Journal of medical virology (01-09-2001)“…A multicentre study was undertaken to define novel assays with increased inter-assay concordance, sensitivity, specificity and predictive value for serological…”
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Inverse Relation of Fas-Ligand and Tumor-Infiltrating Lymphocytes in Angiosarcoma : Indications of Apoptotic Tumor Counterattack
Published in The American journal of pathology (01-09-2001)“…Fas and Fas-L regulate immune responses through the induction of cell death. Fas-L is commonly expressed in activated immune cells and in the endothelium. In…”
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Journal Article -
14
Biology of Kaposi's sarcoma
Published in European journal of cancer (1990) (01-07-2001)“…Kaposi's sarcoma (KS) is an angioproliferative disease occurring in several different clinical-epidemiological forms that, however, share the same histological…”
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Journal Article -
15
Alpha Interferon Inhibits Human Herpesvirus 8 (HHV-8) Reactivation in Primary Effusion Lymphoma Cells and Reduces HHV-8 Load in Cultured Peripheral Blood Mononuclear Cells
Published in Journal of Virology (01-05-1999)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Autonomously vascularized cellular constructs in tissue engineering: opening a new perspective for biomedical science
Published in Journal of cellular and molecular medicine (01-01-2007)“…• Introduction • Cellular homeostasis and vascularization • Importance of vascularization: historical review • Multicellular implants in vivo • Models of…”
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HHV-8 and multistep tumorigenesis
Published in Trends in microbiology (Regular ed.) (01-08-1999)Get full text
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Reduced cytotoxicity by mutation of lysine 590 of Pseudomonas exotoxin can be restored in an optimized, lysine-free immunotoxin
Published in Immunotherapy advances (01-01-2022)“…Abstract Immunotoxins, which are fusion proteins of an antibody fragment and a fragment of a bacterial or a plant toxin, induce apoptosis in target cells by…”
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Predictive value of PD-L1 based on mRNA level in the treatment of stage IV melanoma with ipilimumab
Published in Journal of cancer research and clinical oncology (01-10-2017)“…Introduction PD-L1 is established as a predictive marker for therapy of non-small cell lung cancer with pembrolizumab. Furthermore, PD-L1 positive melanoma has…”
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Serum concentrations of fibroblast growth factor 2 are increased in HIV type 1-infected patients and inversely related to survival probability
Published in AIDS research and human retroviruses (20-07-2001)“…HIV-1-infected patients develop a generalized vasculopathy that is clinically most evident as Kaposi's sarcoma (KS), a multifocally appearing endothelial…”
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