Search Results - "Sturk, Augueste"

Classification, functions, and clinical relevance of extracellular vesicles by van der Pol, Edwin, Böing, Anita N, Harrison, Paul, Sturk, Augueste, Nieuwland, Rienk

“…Both eukaryotic and prokaryotic cells release small, phospholipid-enclosed vesicles into their environment. Why do cells release vesicles? Initial studies…”
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Circulating erythrocyte-derived microparticles are associated with coagulation activation in sickle cell disease by VAN BEERS, Eduard J, SCHAAP, Marianne C. L, BERCKMANS, René J, NIEUWLAND, Rienk, STURK, Augueste, VAN DOORMAAL, Frederiek F, MEIJERS, Joost C. M, BIEMOND, Bart J

“…Sickle cell disease is characterized by a hypercoagulable state as a result of multiple factors, including chronic hemolysis and circulating cell-derived…”
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Inhibition of microparticle release triggers endothelial cell apoptosis and detachment by Abid Hussein, Mohammed N, Böing, Anita N, Sturk, Augueste, Hau, Chi M, Nieuwland, Rienk

“…Endothelial cell cultures contain caspase 3-containing microparticles (EMP), which are reported to form during or after cell detachment. We hypothesize that…”
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P-Selectin- and CD63-Exposing Platelet Microparticles Reflect Platelet Activation in Peripheral Arterial Disease and Myocardial Infarction by van der Zee, P. Marc, Biro, Eva, Ko, Yung, de Winter, Robbert J, Hack, C. Erik, Sturk, Augueste, Nieuwland, Rienk

“…Platelet-derived microparticles (PMPs) are generally considered a marker of platelet activation in cardiovascular disease. We studied the extent to which PMP…”
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Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation by Berckmans, R J, Nieuwland, R, Böing, A N, Romijn, F P, Hack, C E, Sturk, A

“…We determined the numbers, cellular origin and thrombin-generating properties of microparticles in healthy individuals (n = 15). Microparticles, isolated from…”
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Cellular origin and procoagulant properties of microparticles in meningococcal sepsis by Nieuwland, Rienk, Berckmans, René J., McGregor, Sarah, Böing, Anita N., Th. M. Romijn, Fred P.H., Westendorp, Rudi G.J., Hack, C. Erik, Sturk, Augueste

“…Patients with meningococcal sepsis generally suffer from disseminated intravascular coagulation (DIC). The aim of this study was to address whether these…”
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Simvastatin-induced endothelial cell detachment and microparticle release are prenylation dependent by Diamant, Michaela, Tushuizen, Maarten E, Abid-Hussein, Mohammed N, Hau, Chi M, Böing, Anita N, Sturk, Augueste, Nieuwland, Rienk

“…Statins reduce cardiovascular disease risk and affect endothelial function by cholesterol-dependent and independent mechanisms. Recently, circulating…”
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Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes by Berckmans, René J, Nieuwland, Rienk, Kraan, Maarten C, Schaap, Marianne C L, Pots, Desirée, Smeets, Tom J M, Sturk, Augueste, Tak, Paul P

“…Synovial fluid from patients with various arthritides contains procoagulant, cell-derived microparticles. Here we studied whether synovial microparticles…”
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Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms by Joop, K, Berckmans, R J, Nieuwland, R, Berkhout, J, Romijn, F P, Hack, C E, Sturk, A

“…We investigated the occurrence and thrombin generating mechanisms of circulating microparticles (MP) in patients with multiple organ dysfunction syndrome…”
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Microparticle subpopulations are increased in preeclampsia: Possible involvement in vascular dysfunction? by VanWijk, Marja J., Nieuwland, Rienk, Boer, Kees, van der Post, Joris A.M., VanBavel, Ed, Sturk, Augueste

“…Objective: The purpose of this study was to investigate the cellular origin and numbers of circulating microparticles in normal pregnancy and preeclampsia…”
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Microparticle-associated P-selectin reflects platelet activation in preeclampsia by Lok, Christine A. R., Nieuwland, Rienk, Sturk, Augueste, Hau, Chi M., Boer, Kees, Vanbavel, Ed, Vanderpost, Joris A. M.

“…Platelet activation in preeclampsia is reflected by elevated levels of platelets exposing P-selectin. In plasma, a non-cell bound (soluble) form of P-selectin…”
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Relation of N-Terminal Pro B-Type Natriuretic Peptide Levels After Symptom-Limited Exercise to Baseline and Ischemia Levels by van der Zee, P. Marc, MD, Verberne, Hein J., MD, PhD, van Spijker, Rianne C, van Straalen, Jan P, Fischer, Johan C., PhD, Sturk, Augueste, PhD, van Eck-Smit, Berthe L.F., MD, PhD, de Winter, Robbert J., MD, PhD

“…Circulating levels of B-type natriuretic peptide (BNP) and the amino-terminal portion of the prohormone (NT-proBNP) have been reported to increase immediately…”
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Why do cells release vesicles? by Nieuwland, Rienk, Sturk, Augueste

“…Abstract Prokaryotic and eukaryotic cells release vesicles into their environment. To answer the question why eukaryotic cells release vesicles, we may learn…”
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The influence on INRs and coagulation factors of the time span between blood sample collection and intake of phenprocoumon or acenocoumarol: consequences for the assessment of the dose by van Geest-Daalderop, Johanna H H, Hutten, Barbara A, Péquériaux, Nathalie C V, Haas, Fred J L M, Levi, Marcel, Sturk, Augueste

“…Managing treatment with vitamin K antagonists, the prothrombin time (PT), expressed as international normalized ratio (INR), may not represent the INR during…”
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Enhanced coagulation activation in preeclampsia: the role of APC resistance, microparticles and other plasma constituents by VanWijk, Marja J, Boer, Kees, Berckmans, René J, Meijers, Joost C M, van der Post, Joris A M, Sturk, Augueste, VanBavel, Ed, Nieuwland, Rienk

“…Coagulation activation in pregnancy is further enhanced in preeclampsia. We investigated whether this results from increased thrombin generation by the plasma…”
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Cell Saver device efficiently removes cell-derived microparticles during cardiac surgery by van den Goor, Jeanette M., MSc, Nieuwland, Rienk, PhD, van Oeveren, Willem, PhD, Rutten, Peter M, Tijssen, Jan G., MSc, PhD, Hau, Chi M., BSc, Sturk, Augueste, PhD, Eijsman, León, MD, PhD, de Mol, Bas A., MD, PhD

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Cell-Derived Microparticles in the Pathogenesis of Cardiovascular Disease: Friend or Foe? by Tushuizen, Maarten E, Diamant, Michaela, Sturk, Augueste, Nieuwland, Rienk

“…Microparticles are ascribed important roles in coagulation, inflammation, and endothelial function. These processes are mandatory to safeguard the integrity of…”
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Low-dose and high-dose aprotinin improve hemostasis in coronary operations by Speekenbrink, Ron G.H., Wildevuur, Charles R.H., Sturk, Augueste, Eijsman, Leon

“…Prophylactic aprotinin therapy has become a popular method to reduce bleeding associated with cardiac operations. Today essentially two dose regimens are used,…”
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Why do cells release vesicles?: Factor VIIA and Tissue Factor: from Cell Biology to Animal Models, 29 April-1 May 2010, Chapel Hill, North Carolina, USA by NIEUWLAND, Rienk, STURK, Augueste

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Elevated numbers of tissue-factor exposing microparticles correlate with components of the metabolic syndrome in uncomplicated type 2 diabetes mellitus by DIAMANT, Michaela, NIEUWLAND, Rienk, PABLO, Renée F, STURK, Augueste, SMIT, Jan W. A, RADDER, Jasper K

“…Type 2 diabetes is associated with accelerated atherosclerosis. Because cell-derived microparticles support coagulation and inflammation, they may be involved…”
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