Search Results - "Stump, D.G"

Developmental toxicity in rats of a hemoglobin-based oxygen carrier results from impeded function of the inverted visceral yolk sac by Stump, D.G., Holson, J.F., Harris, C., Pearce, L.B., Watson, R.E., DeSesso, J.M.

“…•Infusion HBOC into pregnant rats causes developmental toxicity.•Sensitive from GD 7 to 11 when inverted yolk sac placenta (invYSP) supplies…”
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Evaluation of the prenatal developmental toxicity of orally administered arsenic trioxide in rats by Holson, J.F, Stump, D.G, Clevidence, K.J, Knapp, J.F, Farr, C.H

“…A thorough review of the literature revealed no published repeated-dose oral developmental toxicity studies of inorganic arsenic in rats. In the present study,…”
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Absence of developmental toxicity in a canine model after infusion of a hemoglobin-based oxygen carrier: Implications for risk assessment by Holson, J.F., Stump, D.G., Pearce, L.B., Watson, R.E., DeSesso, J.M.

“…•HBOC infused into pregnant rats interferes with invYSP function.•HBOC interference with invYSP function causes developmental toxicity in rats.•Infusion of…”
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Reproductive toxicity studies with octamethylcyclotetrasiloxane in female rats using various exposure regimens by Reynolds, V.L., DeSesso, J.M., Mast, R.W., Stump, D.G., Holson, J.F.

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Cloning and expression of a pharmacologically unique bovine peripheral-type benzodiazepine receptor isoquinoline binding protein by A L Parola, D G Stump, D J Pepperl, K E Krueger, J W Regan, H E Laird, 2nd

“…High affinity binding of isoquinolines, such as PK 11195, is a conserved feature of peripheral-type benzodiazepine receptors (PBR) across species. However,…”
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Site-directed mutagenesis of the T4 endonuclease V gene: role of tyrosine-129 and -131 in pyrimidine dimer-specific binding by Stump, Donald G, Lloyd, R. Stephen

“…T4 endonuclease V incises DNA at the sites of pyrimidine dimers through a two-step mechanism. These breakage reactions are preceded by the scanning of…”
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Comparative effects of single intraperitoneal or oral doses of sodium arsenate or arsenic trioxide during in utero development by Stump, D.G., Holson, J.F., Fleeman, T.L., Nemec, M.D., Farr, C.H.

“…Numerous studies have suggested that single‐day intraperitoneal (IP) injection of inorganic arsenic results in failure of neural tube closure and other…”
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