Search Results - "Stummvoll, H."

MicroRNA 155-deficiency leads to decreased autoantibody levels and reduced severity of nephritis and pneumonitis in pristane-induced lupus by Leiss, Harald, Salzberger, Wilhelm, Jacobs, Barbara, Gessl, Irina, Kozakowski, Nicolas, Blüml, Stephan, Puchner, Antonia, Kiss, Attila, Podesser, Bruno K, Smolen, Josef S, Stummvoll, Georg H

“…We herein examine the role of endogenous miR155 in the development of systemic manifestations in pristane induced lupus. Systemic lupus in miR155-deficient and…”
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2019 European League Against Rheumatism/American College of Rheumatology Classification Criteria for Systemic Lupus Erythematosus by Aringer, Martin, Costenbader, Karen, Daikh, David, Brinks, Ralph, Mosca, Marta, Ramsey‐Goldman, Rosalind, Smolen, Josef S., Wofsy, David, Boumpas, Dimitrios T., Kamen, Diane L., Jayne, David, Cervera, Ricard, Costedoat‐Chalumeau, Nathalie, Diamond, Betty, Gladman, Dafna D., Hahn, Bevra, Hiepe, Falk, Jacobsen, Søren, Khanna, Dinesh, Lerstrøm, Kirsten, Massarotti, Elena, McCune, Joseph, Ruiz‐Irastorza, Guillermo, Sanchez‐Guerrero, Jorge, Schneider, Matthias, Urowitz, Murray, Bertsias, George, Hoyer, Bimba F., Leuchten, Nicolai, Tani, Chiara, Tedeschi, Sara K., Touma, Zahi, Schmajuk, Gabriela, Anic, Branimir, Assan, Florence, Chan, Tak Mao, Clarke, Ann Elaine, Crow, Mary K., Czirják, László, Doria, Andrea, Graninger, Winfried, Halda‐Kiss, Bernadett, Hasni, Sarfaraz, Izmirly, Peter M., Jung, Michelle, Kumánovics, Gábor, Mariette, Xavier, Padjen, Ivan, Pego‐Reigosa, José M., Romero‐Diaz, Juanita, Rúa‐Figueroa Fernández, Íñigo, Seror, Raphaèle, Stummvoll, Georg H., Tanaka, Yoshiya, Tektonidou, Maria G., Vasconcelos, Carlos, Vital, Edward M., Wallace, Daniel J., Yavuz, Sule, Meroni, Pier Luigi, Fritzler, Marvin J., Naden, Ray, Dörner, Thomas, Johnson, Sindhu R.

“…Objective To develop new classification criteria for systemic lupus erythematosus (SLE) jointly supported by the European League Against Rheumatism (EULAR) and…”
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Lupus nephritis: prolonged immunoadsorption (IAS) reduces proteinuria and stabilizes global disease activity by STUMMVOLL, Georg H, SCHMALDIENST, Sabine, SMOLEN, Josef S, DERFLER, Kurt, BIESENBACH, Peter

“…Systemic lupus erythematosus (SLE) is characterized by pathogenic autoantibodies, which can be removed by extracorporeal procedures. While previous studies…”
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Immunoadsorption (IAS) for systemic lupus erythematosus by Stummvoll, GH

“…Immunoadsorption (IAS) is used as a rescue therapy in severely ill SLE patients who are refractory to conventional therapies. This extracorporeal method aims…”
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Pristane-induced lupus as a model of human lupus arthritis: evolvement of autoantibodies, internal organ and joint inflammation by Leiss, H, Niederreiter, B, Bandur, T, Schwarzecker, B, Blüml, S, Steiner, G, Ulrich, W, Smolen, JS, Stummvoll, GH

“…Objective Arthritis is frequently seen in human lupus, but rarely in lupus models. Pristane-induced lupus (PIL) can be induced in various mouse strains such as…”
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IgG immunoadsorption reduces systemic lupus erythematosus activity and proteinuria: a long term observational study by Stummvoll, G H, Aringer, M, Smolen, J S, Schmaldienst, S, Jiménez-Boj, E, Hörl, W H, Graninger, W B, Derfler, K

“…Objective: To analyse the effects of rigorous immunoglobulin removal by immunoadsorption (IAS) on proteinuria (primary outcome variable), disease activity…”
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Increased transendothelial migration of scleroderma lymphocytes by Stummvoll, G H, Aringer, M, Grisar, J, Steiner, C W, Smolen, J S, Knobler, R, Graninger, W B

“…Background: CD4+ T lymphocytes play an important part in the pathogenesis of scleroderma (systemic sclerosis, SSc) and predominate in perivascular SSc skin…”
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Cinacalcet HCI (Sensipar/Mimpara) is an effective chronic therapy for hemodialysis patients with secondary hyperparathyroidism by Sterrett, J R, Strom, J, Stummvoll, H K, Bahner, U, Disney, A, Soroka, S D, Corpier, C, Arruda, J A, Schwanauer, L E, Klassen, P S, Olson, K A, Block, G A

“…This 1-year double-blind, placebo-controlled, multicenter study evaluated the long-term safety and efficacy of cinacalcet for the treatment of secondary…”
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Autoantibodies against CD74 in spondyloarthritis by Baerlecken, N T, Nothdorft, S, Stummvoll, G H, Sieper, J, Rudwaleit, M, Reuter, S, Matthias, T, Schmidt, R E, Witte, T

“…Spondyloarthritis (SpA) is a common debilitating inflammatory disorder. Establishing the diagnosis is often difficult, since abnormalities in conventional…”
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Regulatory T cell-deficient scurfy mice develop systemic autoimmune features resembling lupus-like disease by Hadaschik, Eva N, Wei, Xiaoying, Leiss, Harald, Heckmann, Britta, Niederreiter, Birgit, Steiner, Günter, Ulrich, Walter, Enk, Alexander H, Smolen, Josef S, Stummvoll, Georg H

“…Scurfy mice are deficient in regulatory T cells (Tregs), develop a severe, generalized autoimmune disorder that can affect almost every organ and die at an…”
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Leflunomide inhibits transendothelial migration of peripheral blood mononuclear cells by Grisar, J, Aringer, M, Köller, M D, Stummvoll, G H, Eselböck, D, Zwölfer, B, Steiner, C W, Zierhut, B, Wagner, L, Pietschmann, P, Smolen, J S

“…Objectives: To test whether the active metabolite of leflunomide (LEF-M), in addition to blocking the proliferation of activated lymphocytes by inhibiting…”
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Th1, Th2, and Th17 Effector T Cell-Induced Autoimmune Gastritis Differs in Pathological Pattern and in Susceptibility to Suppression by Regulatory T Cells by Stummvoll, Georg H, DiPaolo, Richard J, Huter, Eva N, Davidson, Todd S, Glass, Deborah, Ward, Jerrold M, Shevach, Ethan M

“…Th cells can be subdivided into IFN-gamma-secreting Th1, IL-4/IL-5-secreting Th2, and IL-17-secreting Th17 cells. We have evaluated the capacity of fully…”
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Cutting edge: antigen-specific TGF beta-induced regulatory T cells suppress Th17-mediated autoimmune disease by Huter, Eva N, Stummvoll, Georg H, DiPaolo, Richard J, Glass, Deborah D, Shevach, Ethan M

“…CD4(+) T cells from the TCR transgenic TxA23 mouse recognize a peptide from the H/K-ATPase alpha-chain. When TxA23 CD4(+) thymocytes are differentiated into…”
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Cancer polyarthritis resembling rheumatoid arthritis as a first sign of hidden neoplasms: Report of two cases and review of the literature by STUMMVOLL, G. H, ARINGER, M, MACHOLD, K. P, SMOLEN, J. S, RADERER, M

“…Recent onset arthritis reminiscent of rheumatoid arthritis (RA) may be an early manifestation of an occult malignancy. In this report, we present two patients…”
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Increased bioactive TNF in human systemic lupus erythematosus: associations with cell death by Aringer, M, Feierl, E, Steiner, G, Stummvoll, G H, Höfler, E, Steiner, C W, Radda, I, Smolen, J S, Graninger, W B

“…In systemic lupus erythematosus (SLE) serum TNF is increased and correlates with its soluble receptors and with disease activity. We therefore investigated (i)…”
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Serum interleukin‐15 is elevated in systemic lupus erythematosus by Aringer, M., Stummvoll, G. H., Steiner, G., Köller, M., Steiner, C. W., Höfler, E., Hiesberger, H., Smolen, J. S., Graninger, W. B.

“…Objective. To investigate if interleukin‐15 (IL‐15) (rather than IL‐2) is increased in systemic lupus erythematosus (SLE) and might be responsible for…”
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Working capacity is increased following recombinant human erythropoietin treatment by Mayer, Gert, Thum, Johanna, Cada, Eva Maria, Stummvoll, Hans Krister, Graf, Helmut

“…Working capacity is increased following recombinant human erythropoietin treatment. To investigate the effect of partial correction of anemia in patients…”
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Blood–membrane interaction in hemodialysis leads to increased cytokine production by Luger, Anton, Kovarik, Josef, Stummvoll, Hans–Krister, Urbanska, Agatha, Luger, Thomas A.

“…Blood–membrane interaction in hemodialysis leads to increased cytokine production. Recently much interest has been focused on the role of immunoregulatory…”
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Derangement of apoptosis‐related lymphocyte homeostasis in systemic sclerosis by Stummvoll, G. H., Aringer, M., Smolen, J. S., Köller, M., Kiener, H. P., Steiner, C. W., Bohle, B., Knobler, R., Graninger, W. B.

“…Objectives. Both increased and decreased apoptosis may be involved in generating autoimmunity. This study addressed the question of whether apoptosis and…”
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Engulfed cell remnants, and not cells undergoing apoptosis, constitute the LE-cell phenomenon by Feierl, Eva, Smolen, Josef S, Karonitsch, Thomas, Stummvoll, Georg H, Ekhart, Hannelore, Steiner, Carl Walter, Aringer, Martin

“…The LE cell has been one of the first immunological signs of active systemic lupus erythematosus, included into the ACR criteria. LE cells consist of a…”
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