Search Results - "Stul, M"

Use of c-KIT/PDGFRA mutational analysis to predict the clinical response to imatinib in patients with advanced gastrointestinal stromal tumours entered on phase I and II studies of the EORTC Soft Tissue and Bone Sarcoma Group by Debiec-Rychter, M., Dumez, H., Judson, I., Wasag, B., Verweij, J., Brown, M., Dimitrijevic, S., Sciot, R., Stul, M., Vranck, H., Scurr, M., Hagemeijer, A., Van Glabbeke, M., van Oosterom, A.T.

“…Previous studies have shown that activating mutations of c-KIT/ PDGFRA, potential therapeutic targets for imatinib mesylate, are implicated in the…”
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Fusion of NUP214 to ABL1 on amplified episomes in T-cell acute lymphoblastic leukemia by Marynen, Peter, Hagemeijer, Anne, Graux, C, Cools, J, Melotte, C, Quentmeier, H, Ferrando, A, Levine, R, Vermeesch, J.R, Stul, M, Dutta, B, Boeckx, N, Bosly, A, Heimann, P, Uyttebroeck, A, Mentens, N, Somers, R, MacLeod, R.A.F, Drexler, H.G, Look, A.T, Gilliland, D.G, Michaux, L, Vandenberghe, P, Wlodarska, I

“…In T-cell acute lymphoblastic leukemia (T-ALL), transcription factors are known to be deregulated by chromosomal translocations, but mutations in protein…”
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Chromosomal translocations independently predict treatment failure, treatment-free survival and overall survival in B-cell chronic lymphocytic leukemia patients treated with cladribine by VAN DEN NESTE, E, ROBIN, V, FERRANT, A, ROBERT, A, MICHAUX, L, FRANCART, J, HAGEMEIJER, A, SLUT, M, VANDENBERGHE, P, DELANNOY, A, SONET, A, DENEYS, V, COSTANTINI, S

“…Chromosomal translocations represent an important prognostic indicator in B-cell chronic lymphocytic leukemia (B-CLL). However, their value had been neither…”
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Changing phenotype of gastrointestinal stromal tumours under imatinib mesylate treatment: a potential diagnostic pitfall by Pauwels, P, Debiec-Rychter, M, Stul, M, De Wever, I, Van Oosterom, A T, Sciot, R

“…Aims : The diagnosis of gastrointesinal stromal tumours (GISTs) is widely based on morphological features and KIT (CD117) immunoreactivity. Most patients with…”
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Interstitial del(14)(q) involving IGH: a novel recurrent aberration in B-NHL by Pospisilova, H, Baens, M, Michaux, L, Stul, M, Van Hummelen, P, Van Loo, P, Vermeesch, J, Jarosova, M, Zemanova, Z, Michalova, K, Van den Berghe, I, Alexander, H D, Hagemeijer, A, Vandenberghe, P, Cools, J, De Wolf-Peeters, C, Marynen, P, Wlodarska, I

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Variant t(2;11)(p11;q13) associated with the IgK-CCND1 rearrangement is a recurrent translocation in leukemic small-cell B-non-Hodgkin lymphoma by WLODARSKA, I, MEEUS, P, STUL, M, THIENPONT, L, WOUTERS, E, MARCELIS, L, DEMUYNCK, H, RUMMENS, J-L, MADOE, V, HAGEMEIJER, A

“…Classical t(11;14)(q13;q32) involving IGH-CCND1 is typically associated with aggressive CD5-positive mantle cell lymphoma (MCL). Recently, we identified the…”
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Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features by DIERLAMM, J, PITTALUGA, S, DE WOLF-PEETERS, C, VAN DEN BERGHE, H, WLODARSKA, I, STUL, M, THOMAS, J, BOOGAERTS, M, MICHAUX, L, DRIESSEN, A, MECUCCI, C, CASSIMAN, J.-J

“…Clinical, histologic, cytogenetic, and molecular genetic data of 31 patients with extranodal, nodal, and splenic marginal zone B-cell lymphoma (MZBCL) are…”
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Marginal zone B-cell lymphomas of different sites share similar cytogenetic and morphologic features [see comments] by Dierlamm, J, Pittaluga, S, Wlodarska, I, Stul, M, Thomas, J, Boogaerts, M, Michaux, L, Driessen, A, Mecucci, C, Cassiman, JJ

“…Clinical, histologic, cytogenetic, and molecular genetic data of 31 patients with extranodal, nodal, and splenic marginal zone B-cell lymphoma (MZBCL) are…”
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Molecular Cloning of Translocation t(1;14)(q21;q32) Defines a Novel Gene (BCL9) at Chromosome 1q21 by Willis, T.G., Zalcberg, I.R., Coignet, L.J.A., Wlodarska, I., Stul, M., Jadayel, D.M., Bastard, C., Treleaven, J.G., Catovsky, D., Silva, M.L.M., Dyer, M.J.S.

“…Abnormalities of chromosome 1q21 are common in B-cell malignancies and have been associated with a poor response to therapy. The nature of the involved gene(s)…”
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Characteristic pattern of chromosomal gains and losses in marginal zone B cell lymphoma detected by comparative genomic hybridization by DIERLAMM, J, ROSENBERG, C, BAKKER-SCHUT, T, CASSIMAN, J. J, RAAP, A. K, DE WOLF-PEETERS, C, VAN DEN BERGHE, H, HAGEMEIJER, A, STUL, M, PITTALUGA, S, WLODARSKA, I, MICHAUX, L, DEHAEN, M, VERHOEF, G, THOMAS, J, DE KELVER, W

“…Marginal zone B cell lymphoma (MZBCL) represents a distinct subtype of B cell non-Hodgkin's lymphoma, which has been recently recognized and defined as a…”
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Translocation t(1;6)(p35.3;p25.2): a new recurrent aberration in 'unmutated' B-CLL by MICHAUX, L, WLODARSKA, I, VAN HOOF, A, FERRANT, A, MARYNEN, P, HAGEMEIJER, A, RACK, K, STUL, M, CRIEL, A, MAEREVOET, M, MARICHAL, S, DEMUYNCK, H, MINEUR, P, KARGAR SAMANI, K

“…Although reciprocal chromosomal translocations are not typical for B-cell chronic lymphocytic leukemia (B-CLL), we identified the novel t(1;6)(p35.3;p25.2) in…”
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Mantle cell lymphoma: a clinicopathological study of 55 cases by Pittaluga, S, Wlodarska, I, Stul, M S, Thomas, J, Verhoef, G, Cassiman, J J, Van den Berghe, H, de Wolf-Peeters, C

“…A recently described unifying proposal for mantle cell lymphoma has led to the formulation of strict diagnostic criteria based on morphology, immunology and…”
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Coexistence of BCL1/CCND1 and CMYC aberrations in blastoid mantle cell lymphoma: a rare finding associated with very poor outcome by Michaux, L, Wlodarska, I, Theate, I, Stul, M, Scheiff, J-M, Deneys, V, Ferrant, A, Hagemeijer, A

“…A patient with mantle cell lymphoma (MCL) of the pleomorphic blastoid subtype is reported. The disease was clinically aggressive and refractory to…”
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Immunoglobulin and T cell receptor gene rearrangement patterns in acute lymphoblastic leukemia are less mature in adults than in children : implications for selection of PCR targets for detection of minimal residual disease by SZCZEPANSKI, T, LANGERAK, A. W, WOLVERS-TETTERO, I. L. M, OSSENKOPPELE, G. J, VERHOEF, G, STUL, M, PETERSEN, E. J, DE BRUIJN, M. A. C, VAN'T VEER, M. B, VAN DONGEN, J. J. M

“…In order to gain insight into immunoglobulin (Ig) and T cell receptor (TCR) gene rearrangements in adult acute lymphoblastic leukemia (ALL), we studied 48…”
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Coexistence of light chain disease and chronic lymphocytic leukaemia, a complex karyotype with a rapid fatal outcome by CASTRYCK, H., VAN DEN DRIESSCHE, M., HAGEMEIJER, A., STUL, M., WYNENDAELE, W., VANDENBERGHE, P., MOERMAN, J.

“…Summary We report on a 48‐year‐old man with concomitantly diagnosed kappa expressing chronic lymphocytic leukaemia (CLL) and lambda light chain disease with…”
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Histiocyte-rich B-cell lymphoma. A distinct clinicopathologic entity possibly related to lymphocyte predominant Hodgkin's disease, paragranuloma subtype by Delabie, J, Vandenberghe, E, Kennes, C, Verhoef, G, Foschini, M P, Stul, M, Cassiman, J J, De Wolf-Peeters, C

“…This study reports six non-Hodgkin's lymphoma cases that we called histiocyte-rich B-cell lymphoma (BCL) because of the prominent reactive histiocytic…”
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Use of dual-color interphase FISH for the detection of inv(16) in acute myeloid leukemia at diagnosis, relapse and during follow-up : a study of 23 patients by MANCINI, M, CEDRONE, M, MECUCCI, C, ALIMENA, G, HAGEMEIJER, A, DIVERIO, D, EMANUEL, B, STUL, M, VRANCKX, H, BRAMA, M, DE CUIA, M. R, NANNI, M, FAZI, F

“…The value of dual-color fluorescence in situ hybridization (FISH) for the detection of inv(16), using two contigs of cosmid probes mapping on both sides of the…”
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KIT mutations and dose selection for imatinib in patients with advanced gastrointestinal stromal tumours by Debiec-Rychter, Maria, Sciot, Raf, Le Cesne, Axel, Schlemmer, Marcus, Hohenberger, Peter, van Oosterom, Allan T., Blay, Jean-Yves, Leyvraz, Serge, Stul, Michel, Casali, Paolo G., Zalcberg, John, Verweij, Jaap, Van Glabbeke, Martine, Hagemeijer, Anne, Judson, Ian

“…A recent randomized EORTC phase III trial, comparing two doses of imatinib in patients with advanced gastrointestinal stromal tumours (GISTs), reported dose…”
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Primary diffuse large B cell lymphoma of the stomach : analysis of somatic mutations in the rearranged immunoglobulin heavy chain variable genes indicates antigen selection by DRIESSEN, A, TIERENS, A, ECTORS, N, STUL, M, PITTALUGA, S, GEBOES, K, DELABIE, J, DE WOLF-PEETERS, C

“…Gastric low grade MALT lymphomas show a pattern of somatic mutations in their rearranged immunoglobulin genes, indicative of antigen selection. This provides…”
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Mechanisms of resistance to imatinib mesylate in gastrointestinal stromal tumors and activity of the PKC412 inhibitor against imatinib-resistant mutants by Debiec-Rychter, Maria, Cools, Jan, Dumez, Herlinde, Sciot, Raf, Stul, Michel, Mentens, Nicole, Vranckx, Hilde, Wasag, Bartosz, Prenen, Hans, Roesel, Johannes, Hagemeijer, Anne, Van Oosterom, Allan, Marynen, Peter

“…Background & Aims: Resistance is a major challenge in the treatment of patients with gastrointestinal stromal tumors (GISTs). We investigated the mechanisms of…”
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