Search Results - "Stuitje, Antoine R"
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Assessing the diagnostic performance of a novel RT-PCR fluorescence method for the detection of human plasmodium species
Published in PloS one (04-08-2022)“…Background Malaria elimination effort is hampered not only by the lack of effective medication but also due to the lack of sensitive diagnostic tools to detect…”
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2
Performance of a novel melting curve-based qPCR assay for malaria parasites in routine clinical practice in non-endemic setting
Published in Malaria journal (22-06-2023)“…High-quality malaria diagnosis is essential for effective treatment and clinical disease management. Microscopy and rapid diagnostic tests are the conventional…”
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3
Validation of a Fast, Robust, Inexpensive, Two-Tiered Neonatal Screening Test algorithm on Dried Blood Spots for Spinal Muscular Atrophy
Published in International journal of neonatal screening (15-05-2019)“…Spinal muscular atrophy (SMA) is one of the leading genetic causes of infant mortality with an incidence of 1:10,000. The recently-introduced antisense…”
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4
new seed-based assay for meiotic recombination in Arabidopsis thaliana
Published in The Plant journal : for cell and molecular biology (01-08-2005)“…Meiotic recombination is a fundamental biological process that plays a central role in the evolution and breeding of plants. We have developed a new seed-based…”
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5
A Mechanism of Drug Action Revealed by Structural Studies of Enoyl Reductase
Published in Science (American Association for the Advancement of Science) (20-12-1996)“…Enoyl reductase (ENR), an enzyme involved in fatty acid biosynthesis, is the target for antibacterial diazaborines and the front-line antituberculosis drug…”
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A study of the structure-activity relationship for diazaborine inhibition of Escherichia coli enoyl-ACP reductase
Published in Journal of molecular biology (25-05-2001)“…Enoyl acyl carrier protein (ACP) reductase catalyses the last reductive step of fatty acid biosynthesis, reducing the enoyl group of a growing fatty acid chain…”
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Common themes in redox chemistry emerge from the X-ray structure of oilseed rape ( Brassica napus) enoyl acyl carrier protein reductase
Published in Structure (London) (15-09-1995)“…Background: Enoyl acyl carrier protein reductase (ENR) catalyzes the NAD(P)H-dependent reduction of trans- Δ2-enoyl acyl carrier protein, an essential step in…”
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8
Molecular basis of triclosan activity
Published in Nature (London) (01-04-1999)“…Triclosan (5-chloro-2-(2,4-dichlorophenoxy) phenol) has been used for more than 30 years as a general antibacterial and antifungal agent, and is found in…”
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9
X-Ray Crystallographic Studies on Butyryl-ACP Reveal Flexibility of the Structure around a Putative Acyl Chain Binding Site
Published in Structure (London) (01-06-2002)“…Acyl carrier protein (ACP) is an essential cofactor in biosynthesis of fatty acids and many other reactions that require acyl transfer steps. We have…”
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10
The X-ray structure of Brassica napus β-keto acyl carrier protein reductase and its implications for substrate binding and catalysis
Published in Structure (London) (15-04-2000)“…Background: β-Keto acyl carrier protein reductase (BKR) catalyzes the pyridine-nucleotide-dependent reduction of a 3-oxoacyl form of acyl carrier protein…”
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11
Crystallographic analysis of triclosan bound to enoyl reductase
Published in Journal of molecular biology (26-11-1999)“…Molecular genetic studies with strains of Escherichia coli resistant to triclosan, an ingredient of many anti-bacterial household goods, have suggested that…”
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12
Inhibitor Binding Studies on Enoyl Reductase Reveal Conformational Changes Related to Substrate Recognition
Published in The Journal of biological chemistry (22-10-1999)“…Enoyl acyl carrier protein reductase (ENR) is involved in fatty acid biosynthesis. In Escherichia colithis enzyme is the target for the experimental family of…”
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13
Flavonoid synthesis in Petunia hybrida: partial characterization of dihydroflavonol-4-reductase genes
Published in Plant molecular biology (01-11-1989)“…In this paper we describe the organization and expression of the genes encoding the flavonoid-biosynthetic enzyme dihydroflavonol-4-reductase (DFR) in Petunia…”
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14
An anti-sense chalcone synthase gene in transgenic plants inhibits flower pigmentation
Published in Nature (London) (30-06-1988)“…In most plants flower pigments derive from the flavonoid biosynthesis pathway. A description of the constitutive expression of an "anti-sense" chalcone…”
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15
Crystallization and preliminary X-ray crystallographic studies on acyl-(acyl carrier protein) from Escherichia coli
Published in Acta crystallographica. Section D, Biological crystallography. (01-02-2002)“…Acyl carrier proteins carry the lipid substrate to the enzymes of the fatty acid synthase system. Crystals of Escherichia coli acyl carrier protein to which a…”
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Sequences surrounding the transcription initiation site of the Arabidopsis enoyl-acyl carrier protein reductase gene control seed expression in transgenic tobacco
Published in Plant molecular biology (01-04-1999)“…The NADH-specific enoyl-acyl carrier protein (ACP) reductase, which catalyses the last reducing step during the fatty acid biosynthesis cycle, is encoded in…”
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17
Functional analysis of MADS-box genes controlling ovule development in Arabidopsis using the ethanol-inducible alc gene-expression system
Published in Mechanisms of development (01-04-2006)“…In Arabidopsis, different combinations of ABC organ identity proteins interact in the presence of SEPALLATA (SEP) proteins to regulate floral organ…”
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18
Assessing the diagnostic performance of a novel RT-PCR fluorescence method for the detection of human plasmodium species
Published in PloS one (01-01-2022)“…BackgroundMalaria elimination effort is hampered not only by the lack of effective medication but also due to the lack of sensitive diagnostic tools to detect…”
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Journal Article -
19
cDNA cloning and expression of Brassica napus enoyl-acyl carrier protein reductase in Escherichia coli
Published in Plant molecular biology (01-10-1991)“…The onset of storage lipid biosynthesis during seed development in the oilseed crop Brassica napus (rape seed) coincides with a drastic qualitative and…”
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The TACPyAT repeats in the chalcone synthase promoter of Petunia hybrida act as a dominant negative cis‐acting module in the control of organ‐specific expression
Published in The Plant journal : for cell and molecular biology (01-07-1992)“…Summary Analysis of the expression of the GUS reporter gene driven by various region of the Petunia hybrida chalcone synthase (chsA) promoter revealed that the…”
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