Search Results - "Studzińska, Renata"

Synthesis of Carborane-Thiazole Conjugates as Tyrosinase and 11β-Hydroxysteroid Dehydrogenase Inhibitors: Antiproliferative Activity and Molecular Docking Studies by Donarska, Beata, Cytarska, Joanna, Kołodziej-Sobczak, Dominika, Studzińska, Renata, Kupczyk, Daria, Baranowska-Łączkowska, Angelika, Jaroch, Karol, Szeliska, Paulina, Bojko, Barbara, Różycka, Daria, Olejniczak, Agnieszka B, Płaziński, Wojciech, Łączkowski, Krzysztof Z

“…The presented study depicts the synthesis of 11 carborane-thiazole conjugates with anticancer activity, as well as an evaluation of their biological activity…”
Get full text

Glucocorticosteroids – a new target in the treatment of metabolic syndrome by Baumgart, Szymon, Kupczyk, Daria, Studzińska, Renata

“…Glukokortykoidy są hormonami należącymi do grupy hormonów steroidowych wytwarzanych przez korę nadnerczy i są one niezbędne do prawidłowego utrzymania funkcji…”
Get full text

Novel Isosteviol-Based FXa Inhibitors: Molecular Modeling, In Silico Design and Docking Simulation by Gackowski, Marcin, Madriwala, Burhanuddin, Studzińska, Renata, Koba, Marcin

“…Direct oral anticoagulants are an important and relatively new class of synthetic anticoagulant drugs commonly used for the pharmacotherapy of thromboembolic…”
Get full text

A Review of Biologically Active Oxime Ethers by Kosmalski, Tomasz, Kupczyk, Daria, Baumgart, Szymon, Paprocka, Renata, Studzińska, Renata

“…Oxime ethers are a class of compounds containing the >C=N-O-R moiety. The presence of this moiety affects the biological activity of the compounds. In this…”
Get full text

Lipophilic Studies and In Silico ADME Profiling of Biologically Active 2-Aminothiazol-4(5 H )-one Derivatives by Redka, Małgorzata, Baumgart, Szymon, Kupczyk, Daria, Kosmalski, Tomasz, Studzińska, Renata

“…Pseudothiohydantoin derivatives have a wide range of biological activities and are widely used in the development of new pharmaceuticals. Lipophilicity is a…”
Get full text

The Application of Green Solvents in the Synthesis of S -Heterocyclic Compounds-A Review by Kosmalski, Tomasz, Kołodziejska, Renata, Przybysz, Monika, Szeleszczuk, Łukasz, Pawluk, Hanna, Mądra-Gackowska, Katarzyna, Studzińska, Renata

“…Cyclic organic compounds containing sulfur atoms constitute a large group, and they play an important role in the chemistry of heterocyclic compounds. They are…”
Get full text

The Oxime Ethers with Heterocyclic, Alicyclic and Aromatic Moiety as Potential Anti-Cancer Agents by Kosmalski, Tomasz, Hetmann, Anna, Studzińska, Renata, Baumgart, Szymon, Kupczyk, Daria, Roszek, Katarzyna

“…Chemotherapy is one of the most commonly used methods of cancer disease treatment. Due to the acquisition of drug resistance and the possibility of cancer…”
Get full text

Assessment of the concentration of selected metalloproteinases (MMP-2, MMP-3, MMP-9 and MMP-13) in patients with ulcers as a complication of type 2 diabetes by Kupczyk, Daria, Bilski, Rafał, Studziñska, Renata, Woźniak, Alina

“…Impaired chronic wound healing is a great challenge for modern medicine. This process causes ulceration especially in the course of diseases such as type II…”
Get full text

11β-HSD as a New Target in Pharmacotherapy of Metabolic Diseases by Kupczyk, Daria, Bilski, Rafał, Kozakiewicz, Mariusz, Studzińska, Renata, Kędziora-Kornatowska, Kornelia, Kosmalski, Tomasz, Pedrycz-Wieczorska, Agnieszka, Głowacka, Mariola

“…Glucocorticoids (GCs), which are secreted by the adrenal cortex, are important regulators in the metabolism of carbohydrates, lipids, and proteins. For the…”
Get full text

A Novel N-Tert -Butyl Derivatives of Pseudothiohydantoin as Potential Target in Anti-Cancer Therapy by Kupczyk, Daria, Studzińska, Renata, Baumgart, Szymon, Bilski, Rafał, Kosmalski, Tomasz, Kołodziejska, Renata, Woźniak, Alina

“…Tumors are currently more and more common all over the world; hence, attempts are being made to explain the biochemical processes underlying their development…”
Get full text

Novel 2-(Adamantan-1-ylamino)Thiazol-4(5H)-One Derivatives and Their Inhibitory Activity towards 11β-HSD1—Synthesis, Molecular Docking and In Vitro Studies by Studzińska, Renata, Kupczyk, Daria, Płaziński, Wojciech, Baumgart, Szymon, Bilski, Rafał, Paprocka, Renata, Kołodziejska, Renata

“…A common mechanism in which glucocorticoids participate is suggested in the pathogenesis of such metabolic diseases as obesity, metabolic syndrome, or…”
Get full text

Synthesis of Novel 2-(Cyclopentylamino)thiazol-4(5 H )-one Derivatives with Potential Anticancer, Antioxidant, and 11β-HSD Inhibitory Activities by Baumgart, Szymon, Kupczyk, Daria, Archała, Aneta, Koszła, Oliwia, Sołek, Przemysław, Płaziński, Wojciech, Płazińska, Anita, Studzińska, Renata

“…In this study, a series of nine new 2-(cyclopentylamino)thiazol-4(5 )-one derivatives were synthesized, and their anticancer, antioxidant, and…”
Get full text

Synthesis of Novel 2-(Isopropylamino)thiazol-4(5 H )-one Derivatives and Their Inhibitory Activity of 11β-HSD1 and 11β-HSD2 in Aspect of Carcinogenesis Prevention by Kupczyk, Daria, Studzińska, Renata, Bilski, Rafał, Baumgart, Szymon, Kołodziejska, Renata, Woźniak, Alina

“…Glucocorticoid metabolism at the tissue level is regulated by two isoenzymes 11β-hydroxysteroid dehydrogenase (11β-HSD), which mutually convert biologically…”
Get full text

Microbial Synthesis of ( S )- and ( R )-Benzoin in Enantioselective Desymmetrization and Deracemization Catalyzed by Aureobasidium pullulans Included in the Blossom Protect™ Agent by Kołodziejska, Renata, Studzińska, Renata, Tafelska-Kaczmarek, Agnieszka, Pawluk, Hanna, Mlicka, Dominika, Woźniak, Alina

“…In this study, we examined the strains DSM 14940 and DSM 14941 included in the Blossom Protect™ agent to be used in the bioreduction reaction of a symmetrical…”
Get full text

Novel Thiourea and Oxime Ether Isosteviol-Based Anticoagulants: MD Simulation and ADMET Prediction by Gackowski, Marcin, Jędrzejewski, Mateusz, Medicharla, Sri Satya, Kondabala, Rajesh, Madriwala, Burhanuddin, Mądra-Gackowska, Katarzyna, Studzińska, Renata

“…Activated blood coagulation factor X (FXa) plays a critical initiation step of the blood-coagulation pathway and is considered a desirable target for…”
Get full text

A Review of the Biological Activity of Amidrazone Derivatives by Paprocka, Renata, Wiese-Szadkowska, Małgorzata, Kosmalski, Tomasz, Frisch, Daria, Ratajczak, Magdalena, Modzelewska-Banachiewicz, Bożena, Studzińska, Renata

“…Amidrazones are widely used in chemical synthesis, industry and agriculture. We compiled some of the most important findings on the biological activities of…”
Get full text

Concentration of proinflammatory cytokines in patients with ulcers as a complication of type 2 diabetes mellitus by Kupczyk, Daria, Bilski, Rafał, Przewięźlikowski, Andrzej, Studziñska, Renata, Woźniak, Alina

“…Difficult healing of chronic wounds is a serious problem for modern medicine. It leads to ulceration, especially in conditions such as diabetic foot syndrome…”
Get full text

Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors by Woźniak, Alina, Bilski, Rafał, Studzińska, Renata, Kupczyk, Daria

“…The metabolic syndrome is defined by impaired carbohydrate metabolism and lipid disorders and often accompanied by hypertension, all of which will lead to…”
Get full text

Microbiological bio-reduction of prochiral carbonyl compounds by antimycotic agent Boni Protect by Kołodziejska, Renata, Studzińska, Renata, Kwit, Marcin, Jelecki, Maciej, Tafelska-Kaczmarek, Agnieszka

“…The selective properties of the fungus Aureobasidium pullulans, in the antifungal agent Boni Protect, were investigated in the fermentative bioreduction of…”
Get full text

Lipase‐catalyzed enantioselective transesterification of prochiral 1‐((1,3‐dihydroxypropan‐2‐yloxy)methyl)‐5,6,7,8‐tetrahydroquinazoline‐2,4(1H,3H)‐dione in ionic liquids by Kołodziejska, Renata, Studzińska, Renata, Pawluk, Hanna

“…The application of ionic liquids as solvents for transesterification of prochiral pirymidine acyclonucleoside using lipase (EC 3.1.1.3) Amano PS from…”
Get full text