Search Results - "Studer, Michele"

Geniculocortical Input Drives Genetic Distinctions Between Primary and Higher-Order Visual Areas by Chou, Shen-Ju, Babot, Zoila, Leingärtner, Axel, Studer, Michele, Nakagawa, Yasushi, O'Leary, Dennis D. M.

“…Studies of area patterning of the neocortex have focused on primary areas, concluding that the primary visual area, V1, is specified by transcription factors…”
Get full text

The pleiotropic transcriptional regulator COUP-TFI plays multiple roles in neural development and disease by Bertacchi, Michele, Parisot, Josephine, Studer, Michèle

“…•COUP-TFI transcriptional action depends on cellular context and co-factor accessibility.•COUP‐TFI imparts sensory identity during neocortical area map…”
Get full text

Developmental genetic programs and activity-dependent mechanisms instruct neocortical area mapping by Simi, Alessandro, Studer, Michèle

“…The subdivision of the mammalian neocortex into specialized modality-specific areas is responsible for the processing of sensory information followed by an…”
Get full text

Mitochondrial regulation of adult hippocampal neurogenesis: Insights into neurological function and neurodevelopmental disorders by Bonzano, Sara, Dallorto, Eleonora, Bovetti, Serena, Studer, Michèle, De Marchis, Silvia

“…Mitochondria are essential regulators of cellular energy metabolism and play a crucial role in the maintenance and function of neuronal cells. Studies in the…”
Get full text

Structural and Functional Aspects of the Neurodevelopmental Gene NR2F1 : From Animal Models to Human Pathology by Tocco, Chiara, Bertacchi, Michele, Studer, Michèle

“…The assembly and maturation of the mammalian brain result from an intricate cascade of highly coordinated developmental events, such as cell proliferation,…”
Get full text

Molecular control of two novel migratory paths for CGE-derived interneurons in the developing mouse brain by Touzot, Audrey, Ruiz-Reig, Nuria, Vitalis, Tania, Studer, Michèle

“…GABAergic interneurons are highly heterogeneous and originate in the subpallium mainly from the medial (MGE) and caudal (CGE) ganglionic eminences according to…”
Get full text

Area-specific development of distinct projection neuron subclasses is regulated by postnatal epigenetic modifications by Harb, Kawssar, Magrinelli, Elia, Nicolas, Céline S, Lukianets, Nikita, Frangeul, Laura, Pietri, Mariel, Sun, Tao, Sandoz, Guillaume, Grammont, Franck, Jabaudon, Denis, Studer, Michele, Alfano, Christian

“…During cortical development, the identity of major classes of long-distance projection neurons is established by the expression of molecular determinants,…”
Get full text

Krox20 defines a subpopulation of cardiac neural crest cells contributing to arterial valves and bicuspid aortic valve by Odelin, Gaëlle, Faure, Emilie, Coulpier, Fanny, Di Bonito, Maria, Bajolle, Fanny, Studer, Michèle, Avierinos, Jean-François, Charnay, Patrick, Topilko, Piotr, Zaffran, Stéphane

“…Although cardiac neural crest cells are required at early stages of arterial valve development, their contribution during valvular leaflet maturation remains…”
Get full text

Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion by Marino, Valerio, Phromkrasae, Wanchana, Bertacchi, Michele, Cassini, Paul, Chakrabandhu, Krittalak, Dell'Orco, Daniele, Studer, Michèle

“…Deciphering the structural effects of gene variants is essential for understanding the pathophysiological mechanisms of genetic diseases. Using a…”
Get full text

Neocortical arealization: Evolution, mechanisms, and open questions by Alfano, Christian, Studer, Michèle

“…The mammalian neocortex is a structure with no equals in the vertebrates and is the seat of the highest cerebral functions, such as thoughts and consciousness…”
Get full text

The topography of corticopontine projections is controlled by postmitotic expression of the area-mapping gene Nr2f1 by Tocco, Chiara, Øvsthus, Martin, Bjaalie, Jan G, Leergaard, Trygve B, Studer, Michèle

“…Axonal projections from layer V neurons of distinct neocortical areas are topographically organized into discrete clusters within the pontine nuclei during the…”
Get full text

Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities by Felske, Torsten, Tocco, Chiara, Péron, Sophie, Harb, Kawssar, Alfano, Christian, Galante, Chiara, Berninger, Benedikt, Studer, Michèle

“…In vivo direct neuronal reprogramming relies on the implementation of an exogenous transcriptional program allowing to achieve conversion of a particular…”
Get full text

Abnormal outer hair cell efferent innervation in Hoxb1-dependent sensorineural hearing loss by Di Bonito, Maria, Bourien, Jérôme, Tizzano, Monica, Harrus, Anne-Gabrielle, Puel, Jean-Luc, Avallone, Bice, Nouvian, Regis, Studer, Michèle

“…Autosomal recessive mutation of HOXB1 and Hoxb1 causes sensorineural hearing loss in patients and mice, respectively, characterized by the presence of higher…”
Get full text

Neuron-Astroglia Cell Fate Decision in the Adult Mouse Hippocampal Neurogenic Niche Is Cell-Intrinsically Controlled by COUP-TFI In Vivo by Bonzano, Sara, Crisci, Isabella, Podlesny-Drabiniok, Anna, Rolando, Chiara, Krezel, Wojciech, Studer, Michèle, De Marchis, Silvia

“…In the dentate gyrus (DG) of the mouse hippocampus, neurogenesis and astrogliogenesis persist throughout life. Adult-born neurons and astrocytes originate from…”
Get full text

The nuclear hormone receptor Coup-TFII is required for the initiation and early maintenance of Prox1 expression in lymphatic endothelial cells by Srinivasan, R Sathish, Geng, Xin, Yang, Ying, Wang, Yingdi, Mukatira, Suraj, Studer, Michèle, Porto, Marianna P R, Lagutin, Oleg, Oliver, Guillermo

“…The homeobox gene Prox1 is crucial for mammalian lymphatic vascular development. In the absence of Prox1, lymphatic endothelial cells (LECs) are not specified…”
Get full text

Excitatory Projection Neuron Subtypes Control the Distribution of Local Inhibitory Interneurons in the Cerebral Cortex by Lodato, Simona, Rouaux, Caroline, Quast, Kathleen B., Jantrachotechatchawan, Chanati, Studer, Michèle, Hensch, Takao K., Arlotta, Paola

“…In the mammalian cerebral cortex, the developmental events governing the integration of excitatory projection neurons and inhibitory interneurons into balanced…”
Get full text

Why are type II focal cortical dysplasias frequently located at the bottom of sulcus? A neurodevelopmental hypothesis by Studer, Michèle, Rossini, Laura, Spreafico, Roberto, Pelliccia, Veronica, Tassi, Laura, Curtis, Marco, Garbelli, Rita

Get full text

Structural interhemispheric connectivity defects in mouse models of BBSOAS: Insights from high spatial resolution 3D white matter tractography by Deloulme, Jean Christophe, Leclercq, Maxime, Deschaux, Olivier, Flore, Gemma, Capellano, Laetitia, Tocco, Chiara, Braz, Barbara Yael, Studer, Michèle, Lahrech, Hana

“…White matter (WM) tract formation and axonal pathfinding are major processes in brain development allowing to establish precise connections between targeted…”
Get full text

Cellular and Molecular Underpinnings of Neuronal Assembly in the Central Auditory System during Mouse Development by Di Bonito, Maria, Studer, Michèle

“…During development, the organization of the auditory system into distinct functional subcircuits depends on the spatially and temporally ordered sequence of…”
Get full text

nuclear receptors COUP-TF: a long-lasting experience in forebrain assembly by Alfano, Christian, Magrinelli, Elia, Harb, Kawssar, Studer, Michèle

“…Chicken ovalbumin upstream promoter transcription factors (COUP-TFs) are nuclear receptors belonging to the superfamily of the steroid/thyroid hormone…”
Get full text