Search Results - "Stubbs, Sarah H"

Lassa virus entry requires a trigger-induced receptor switch by Jae, Lucas T., Raaben, Matthijs, Herbert, Andrew S., Kuehne, Ana I., Wirchnianski, Ariel S., Soh, Timothy K., Stubbs, Sarah H., Janssen, Hans, Damme, Markus, Saftig, Paul, Whelan, Sean P., Dye, John M., Brummelkamp, Thijn R.

“…Lassa virus spreads from a rodent to humans and can lead to lethal hemorrhagic fever. Despite its broad tropism, chicken cells were reported 30 years ago to…”
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NRP2 and CD63 Are Host Factors for Lujo Virus Cell Entry by Raaben, Matthijs, Jae, Lucas T., Herbert, Andrew S., Kuehne, Ana I., Stubbs, Sarah H., Chou, Yi-ying, Blomen, Vincent A., Kirchhausen, Tomas, Dye, John M., Brummelkamp, Thijn R., Whelan, Sean P.

“…Arenaviruses cause fatal hemorrhagic disease in humans. Old World arenavirus glycoproteins (GPs) mainly engage α-dystroglycan as a cell-surface receptor, while…”
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Reconstruction of the cell entry pathway of an extinct virus by Robinson-McCarthy, Lindsey R, McCarthy, Kevin R, Raaben, Matthijs, Piccinotti, Silvia, Nieuwenhuis, Joppe, Stubbs, Sarah H, Bakkers, Mark J G, Whelan, Sean P J

“…Endogenous retroviruses (ERVs), remnants of ancient germline infections, comprise 8% of the human genome. The most recently integrated includes human ERV-K…”
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Viral Factors Reveal a Role for REF/Aly in Nuclear RNA Stability by Stubbs, Sarah H., Hunter, Olga V., Hoover, Ashley, Conrad, Nicholas K.

“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy by Stubbs, Sarah H, Conrad, Nicholas K

“…Pre-mRNA processing is mechanistically linked to transcription with RNA pol II serving as a platform to recruit RNA processing factors to nascent transcripts…”
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Lrp1 is a host entry factor for Rift Valley fever virus by Ganaie, Safder S., Schwarz, Madeline M., McMillen, Cynthia M., Price, David A., Feng, Annie X., Albe, Joseph R., Wang, Wenjie, Miersch, Shane, Orvedahl, Anthony, Cole, Aidan R., Sentmanat, Monica F., Mishra, Nawneet, Boyles, Devin A., Koenig, Zachary T., Kujawa, Michael R., Demers, Matthew A., Hoehl, Ryan M., Moyle, Austin B., Wagner, Nicole D., Stubbs, Sarah H., Cardarelli, Lia, Teyra, Joan, McElroy, Anita, Gross, Michael L., Whelan, Sean P.J., Doench, John, Cui, Xiaoxia, Brett, Tom J., Sidhu, Sachdev S., Virgin, Herbert W., Egawa, Takeshi, Leung, Daisy W., Amarasinghe, Gaya K., Hartman, Amy L.

“…Rift Valley fever virus (RVFV) is a zoonotic pathogen with pandemic potential. RVFV entry is mediated by the viral glycoprotein (Gn), but host entry factors…”
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Oropouche orthobunyavirus infection is mediated by the cellular host factor Lrp1 by Schwarz, Madeline M, Price, David A, Ganaie, Safder S, Feng, Annie, Mishra, Nawneet, Hoehl, Ryan M, Fatma, Farheen, Stubbs, Sarah H, Whelan, Sean P J, Cui, Xiaoxia, Egawa, Takeshi, Leung, Daisy W, Amarasinghe, Gaya K, Hartman, Amy L

“…Oropouche orthobunyavirus (OROV; ) is a mosquito-transmitted virus that causes widespread human febrile illness in South America, with occasional progression…”
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Disruption of Ebola NP0VP35 Inclusion Body-like Structures reduce Viral Infection by Wu, Chao, Wagner, Nicole D., Moyle, Austin B., Feng, Annie, Sharma, Nitin, Stubbs, Sarah H., Donahue, Callie, Davey, Robert A., Gross, Michael L., Leung, Daisy W., Amarasinghe, Gaya K.

“…•In vitro purified Ebola eNP0VP35 spontaneously phase separates, likely seeding early stages of viral IB assembly.•Construct screening illuminates key…”
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Identification and Characterization of a Novel Broad-Spectrum Virus Entry Inhibitor by Chou, Yi-Ying, Cuevas, Christian, Carocci, Margot, Stubbs, Sarah H, Ma, Minghe, Cureton, David K, Chao, Luke, Evesson, Frances, He, Kangmin, Yang, Priscilla L, Whelan, Sean P, Ross, Susan R, Kirchhausen, Tom, Gaudin, Raphaël

“…Virus entry into cells is a multistep process that often requires the subversion of subcellular machineries. A more complete understanding of these steps is…”
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Identification of potent inhibitors of SARS-CoV-2 infection by combined pharmacological evaluation and cellular network prioritization by Patten, J.J., Keiser, Patrick T., Morselli-Gysi, Deisy, Menichetti, Giulia, Mori, Hiroyuki, Donahue, Callie J., Gan, Xiao, Valle, Italo do, Geoghegan-Barek, Kathleen, Anantpadma, Manu, Boytz, RuthMabel, Berrigan, Jacob L., Stubbs, Sarah H., Ayazika, Tess, O’Leary, Colin, Jalloh, Sallieu, Wagner, Florence, Ayehunie, Seyoum, Elledge, Stephen J., Anderson, Deborah, Loscalzo, Joseph, Zitnik, Marinka, Gummuluru, Suryaram, Namchuk, Mark N., Barabási, Albert-László, Davey, Robert A.

“…Pharmacologically active compounds with known biological targets were evaluated for inhibition of SARS-CoV-2 infection in cell and tissue models to help…”
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Analysis of RNA-protein interactions by cell mixing by Stubbs, Sarah H, Conrad, Nicholas K

“…RNA-protein complexes are critical for almost all aspects of gene expression. Analysis of RNA-protein interactions can be complicated by the disruption of…”
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Disruption of Ebola NP 0 VP35 Inclusion Body-like Structures reduce Viral Infection by Wu, Chao, Wagner, Nicole D, Moyle, Austin B, Feng, Annie, Sharma, Nitin, Stubbs, Sarah H, Donahue, Callie, Davey, Robert A, Gross, Michael L, Leung, Daisy W, Amarasinghe, Gaya K

“…Viral inclusion bodies (IBs) are potential sites of viral replication and assembly. How viral IBs form remains poorly defined. Here we describe a combined…”
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Virus entry. Lassa virus entry requires a trigger-induced receptor switch by Jae, Lucas T, Raaben, Matthijs, Herbert, Andrew S, Kuehne, Ana I, Wirchnianski, Ariel S, Soh, Timothy K, Stubbs, Sarah H, Janssen, Hans, Damme, Markus, Saftig, Paul, Whelan, Sean P, Dye, John M, Brummelkamp, Thijn R

“…Lassa virus spreads from a rodent to humans and can lead to lethal hemorrhagic fever. Despite its broad tropism, chicken cells were reported 30 years ago to…”
Get full text