Search Results - "Stubblefield, Samantha"
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Multipotent adult progenitor cells induce regulatory T cells and promote their suppressive phenotype via TGFβ and monocyte-dependent mechanisms
Published in Scientific reports (30-06-2021)“…Dysregulation of the immune system can initiate chronic inflammatory responses that exacerbate disease pathology. Multipotent adult progenitor cells (MAPC…”
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Circulating CD4+ and CD8+ T cells are activated in inflammatory bowel disease and are associated with plasma markers of inflammation
Published in Immunology (01-09-2013)“…Summary Inflammatory bowel disease (IBD) is characterized by damage to the gut mucosa and systemic inflammation. We sought to evaluate the role of chronic…”
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3
The Delivery of Multipotent Adult Progenitor Cells to Extended Criteria Human Donor Livers Using Normothermic Machine Perfusion
Published in Frontiers in immunology (25-06-2020)“…Pre-clinical research with multi-potent adult progenitor cells (MAPC® cells, Multistem, Athersys Inc., Cleveland, Ohio) suggests their potential as an…”
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4
IFN‐γ and PPARδ influence the efficacy and retention of multipotent adult progenitor cells in graft vs host disease
Published in Stem cells translational medicine (01-11-2021)“…Cell‐based therapy for the treatment of inflammatory disorders has focused on the application of mesenchymal stromal cells (MSCs) and multipotent adult…”
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5
Augmented Expansion of Treg Cells From Healthy and Autoimmune Subjects via Adult Progenitor Cell Co-Culture
Published in Frontiers in immunology (01-09-2021)“…Recent clinical experience has demonstrated that adoptive regulatory T (Treg) cell therapy is a safe and feasible strategy to suppress immunopathology…”
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6
T Cell-, Interleukin-12-, and Gamma Interferon-Driven Viral Clearance in Measles Virus-Infected Brain Tissue
Published in Journal of Virology (01-04-2011)“…Article Usage Stats Services JVI Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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Multipotent Adult Progenitor Cells Suppress T Cell Activation in In Vivo Models of Homeostatic Proliferation in a Prostaglandin E2-Dependent Manner
Published in Frontiers in immunology (23-04-2018)“…Lymphodepletion strategies are used in the setting of transplantation (including bone marrow, hematopoietic cell, and solid organ) to create space or to…”
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8
Discovery and Optimization of Selective Brain-Penetrant EBP Inhibitors that Enhance Oligodendrocyte Formation
Published in Journal of medicinal chemistry (28-03-2024)“…The inhibition of emopamil binding protein (EBP), a sterol isomerase within the cholesterol biosynthesis pathway, promotes oligodendrocyte formation, which has…”
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9
IFN#8208;γ and PPARδ influence the efficacy and retention of multipotent adult progenitor cells in graft vs host disease
Published in Stem cells translational medicine (01-11-2021)“…Cell‐based therapy for the treatment of inflammatory disorders has focused on the application of mesenchymal stromal cells (MSCs) and multipotent adult…”
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Journal Article -
10
Increased small intestinal and colonic permeability, and loss of villus tip surface area, correlates with microbial translocation and immune activation in HIV (71.5)
Published in The Journal of immunology (1950) (01-05-2012)“…Abstract As early diagnosis and viremic control of HIV becomes more prevalent, the clinical focus has turned to preventing co-morbidities that include…”
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Journal Article -
11
Circulating CD 4 + and CD 8 + T cells are activated in inflammatory bowel disease and are associated with plasma markers of inflammation
Published in Immunology (01-09-2013)“…Summary Inflammatory bowel disease ( IBD ) is characterized by damage to the gut mucosa and systemic inflammation. We sought to evaluate the role of chronic…”
Get full text
Journal Article -
12
Organotypic brain explants reveal an interleukin-12 / interferon-gamma / T-cell dependent clearance of measles virus infection
Published 2011“…Genetic studies in immunocompetent mice have shown the importance of both T cells and interferon (IFN)-gamma for animal survival of MV challenge; however, the…”
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Dissertation