Search Results - "Stubbe, Jane"

A Single Injection of ADRCs Does Not Prevent AAA Formation in Rats in a Randomized Blinded Design by Kavaliunaite, Egle, Dhumale, Pratibha, Jensen, Charlotte Harken, Sheikh, Søren P, Lindholt, Jes S, Stubbe, Jane

“…There is a pressing need for alternative medical treatments for abdominal aortic aneurysms (AAAs). Mesenchymal regenerative cells derived from adipose tissue…”
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Intraluminal infusion of Penta-Galloyl Glucose reduces abdominal aortic aneurysm development in the elastase rat model by Schack, Asbjørn Sune, Stubbe, Jane, Steffensen, Lasse Bach, Mahmoud, Hend, Laursen, Malene Skaarup, Lindholt, Jes Sanddal

“…Background An abdominal aortic aneurysm (AAA) is a progressive chronic dilatation of the abdominal aorta with terminally rupture when the aortic wall is so…”
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MFAP4 Promotes Vascular Smooth Muscle Migration, Proliferation and Accelerates Neointima Formation by Schlosser, Anders, Pilecki, Bartosz, Hemstra, Line E, Kejling, Karin, Kristmannsdottir, Gudlaug B, Wulf-Johansson, Helle, Moeller, Jesper B, Füchtbauer, Ernst-Martin, Nielsen, Ole, Kirketerp-Møller, Katrine, Dubey, Lalit K, Hansen, Pernille B.L, Stubbe, Jane, Wrede, Christoph, Hegermann, Jan, Ochs, Matthias, Rathkolb, Birgit, Schrewe, Anja, Bekeredjian, Raffi, Wolf, Eckhard, Gailus-Durner, Valérie, Fuchs, Helmut, Hrabě de Angelis, Martin, Lindholt, Jes S, Holmskov, Uffe, Sorensen, Grith L

“…OBJECTIVE—Arterial injury stimulates remodeling responses that, when excessive, lead to stenosis. These responses are influenced by integrin signaling in…”
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Plasmin in Nephrotic Urine Activates the Epithelial Sodium Channel by SVENNINGSEN, Per, BISTRUP, Claus, JESPERSEN, Bente, JENSEN, Boye L, KORBMACHER, Christoph, SKØTT, Ole, FRIIS, Ulla G, BERTOG, Marko, HAERTEIS, Silke, KRUEGER, Bettina, STUBBE, Jane, JENSEN, Ole Nørregaard, THIESSON, Helle C, UHRENHOLT, Torben R

“…Proteinuria and increased renal reabsorption of NaCl characterize the nephrotic syndrome. Here, we show that protein-rich urine from nephrotic rats and from…”
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Cystathionine gamma-lyase (CTH) inhibition attenuates glioblastoma formation by Peleli, Maria, Antoniadou, Ivi, Rodrigues-Junior, Dorival Mendes, Savvoulidou, Odysseia, Caja, Laia, Katsouda, Antonia, Ketelhuth, Daniel F.J., Stubbe, Jane, Madsen, Kirsten, Moustakas, Aristidis, Papapetropoulos, Andreas

“…Glioblastoma (GBM) is the most common type of adult brain tumor with extremely poor survival. Cystathionine-gamma lyase (CTH) is one of the main Hydrogen…”
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Niacin and biosynthesis of PGD2 by platelet COX-1 in mice and humans by Song, Wen-Liang, Stubbe, Jane, Ricciotti, Emanuela, Alamuddin, Naji, Ibrahim, Salam, Crichton, Irene, Prempeh, Maxwell, Lawson, John A., Wilensky, Robert L., Rasmussen, Lars Melholt, Puré, Ellen, FitzGerald, Garret A.

“…The clinical use of niacin to treat dyslipidemic conditions is limited by noxious side effects, most commonly facial flushing. In mice, niacin-induced flushing…”
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Prostaglandin F₂α elevates blood pressure and promotes atherosclerosis by Yu, Ying, Lucitt, Margaret B, Stubbe, Jane, Cheng, Yan, Friis, Ulla G, Hansen, Pernille B, Jensen, Boye L, Smyth, Emer M, FitzGerald, Garret A

“…Little is known about prostaglandin F₂α in cardiovascular homeostasis. Prostaglandin F₂α dose-dependently elevates blood pressure in WT mice via activation of…”
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Regulation of renin secretion by renal juxtaglomerular cells by Friis, Ulla G., Madsen, Kirsten, Stubbe, Jane, Hansen, Pernille B. L., Svenningsen, Per, Bie, Peter, Skøtt, Ole, Jensen, Boye L.

“…A major rate-limiting step in the renin–angiotensin–aldosterone system is the release of active renin from endocrine cells (juxtaglomerular (JG) cells) in the…”
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Corrigendum: Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression by Griepke, Silke, Grupe, Emilie, Lindholt, Jes Sanddal, Fuglsang, Elizabeth Hvitfeldt, Steffensen, Lasse Bach, Beck, Hans Christian, Larsen, Mia Dupont, Bang-Møller, Sissel Karoline, Overgaard, Martin, Rasmussen, Lars Melholt, Lambertsen, Kate Lykke, Stubbe, Jane

“…[This corrects the article DOI: 10.3389/fcvm.2022.942342.]…”
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Cycloastragenol Inhibits Experimental Abdominal Aortic Aneurysm Progression by Melin, Leander Gaarde, Dall, Julie Husted, Lindholt, Jes S, Steffensen, Lasse B, Beck, Hans Christian, Elkrog, Sophie L, Clausen, Pernille D, Rasmussen, Lars Melholt, Stubbe, Jane

“…The pathogenesis of abdominal aortic aneurysm involves vascular inflammation and elastin degradation. contains cycloastragenol, which is known to be…”
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Nicotine Administration Augments Abdominal Aortic Aneurysm Progression in Rats by Hadzikadunic, Hana, Sjælland, Tea Bøvling, Lindholt, Jes S, Steffensen, Lasse Bach, Beck, Hans Christian, Kavaliunaite, Egle, Rasmussen, Lars Melholt, Stubbe, Jane

“…Inflammation and elastin degradation are key hallmarks in the pathogenesis of abdominal aortic aneurysms (AAAs). It has been acknowledged that activation of…”
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Targeted Deletions of Cyclooxygenase-2 and Atherogenesis in Mice by YIQUN HUI, RICCIOTTI, Emanuela, CRICHTON, Irene, ZHOU YU, DAIRONG WANG, STUBBE, Jane, MIAO WANG, PURE, Ellen, FITZGERALD, Garret A

“…Although the dominant product of vascular Cyclooxygenase-2 (COX-2), prostacyclin (PGI(2)), restrains atherogenesis, inhibition and deletion of COX-2 have…”
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Selective inhibition of soluble tumor necrosis factor signaling reduces abdominal aortic aneurysm progression by Griepke, Silke, Grupe, Emilie, Lindholt, Jes Sanddal, Fuglsang, Elizabeth Hvitfeldt, Steffensen, Lasse Bach, Beck, Hans Christian, Larsen, Mia Dupont, Bang-Møller, Sissel Karoline, Overgaard, Martin, Rasmussen, Lars Melholt, Lambertsen, Kate Lykke, Stubbe, Jane

“…Tumor necrosis factor (TNF) is pathologically elevated in human abdominal aortic aneurysms (AAA). Non-selective TNF inhibition-based therapeutics are approved…”
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Conditional Ablation of Myeloid TNF Improves Functional Outcome and Decreases Lesion Size after Spinal Cord Injury in Mice by Ellman, Ditte Gry, Lund, Minna Christiansen, Nissen, Maiken, Nielsen, Pernille Sveistrup, Sørensen, Charlotte, Lester, Emilie Boye, Thougaard, Estrid, Jørgensen, Louise Helskov, Nedospasov, Sergei A, Andersen, Ditte Caroline, Stubbe, Jane, Brambilla, Roberta, Degn, Matilda, Lambertsen, Kate Lykke

“…Spinal cord injury (SCI) is a devastating condition consisting of an instant primary mechanical injury followed by a secondary injury that progresses for weeks…”
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MFAP4 Deficiency Attenuates Angiotensin II-Induced Abdominal Aortic Aneurysm Formation Through Regulation of Macrophage Infiltration and Activity by Pilecki, Bartosz, de Carvalho, Paulo V. S. D., Kirketerp-Møller, Katrine L., Schlosser, Anders, Kejling, Karin, Dubik, Magdalena, Madsen, Nicklas P., Stubbe, Jane, Hansen, Pernille B. L., Andersen, Thomas L., Moeller, Jesper B., Marcussen, Niels, Azevedo, Vasco, Hvidsten, Svend, Baun, Christina, Shi, Guo-Ping, Lindholt, Jes S., Sorensen, Grith L.

“…Objective: Abdominal aortic aneurysm (AAA) is a common age-related vascular disease characterized by progressive weakening and dilatation of the aortic wall…”
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Cardiovascular Inflammation by Guo, Austin Meng, Jin, Weijun, Wang, Miao, Stubbe, Jane

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Reduction of COL4A1/A2 Causes Dedifferentiation of Vascular Smooth Muscle Cells and Augments Development of Abdominal Aortic Aneurysm by Steffensen, Lasse Bach, Stubbe, Jane, Lindholt, Jes Sanddal, Bloksgaard, Maria, Genovese, Federica, Nielsen, Signe Holm, Bang-Møller, Sissel Karoline, Jones, Greg, Bown, Matt, Overgaard, Martin, Beck, Hans Christian, Karsdal, Morten, Rasmussen, Lars Melholt

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Systemic Eicosanoid and Cytokine Response to Niacin: Implications in HPS2-THRIVE Trial and Beyond by Song, Wenliang, MD, Stubbe, Jane, PhD, Ricciotti, Emanuela, PhD, Dunbar, Richard L., MD, Rader, Daniel J., MD, FitzGerald, Garret A., MD

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Cyclooxygenase-2 contributes to elevated renin in the early postnatal period in rats by Stubbe, Jane, Jensen, Boye L, Bachmann, Sebastian, Morsing, Peter, Skøtt, Ole

“…We asked whether cyclooxygenase (COX) activity controls the renin-angiotensin system in the postnatal period. During kidney development, renin peaked at…”
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With More than 2000 Times Increased Plasma Concentration, Interleukin‐17A Does Not Increase Arterial Blood Pressure in Mice by Thangaraj, Sai, Enggaard, Camilla, Hansen, Pernille, Stubbe, Jane, Palarasah, Yaseelan, Svenningsen, Per, Jensen, Boye

“…Background T‐lymphocytes are important for angiotensin II (ANGII)‐hypertension in mice. T‐helper 17 cells produce the pro‐inflammatory cytokine interleukin‐17…”
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