Search Results - "Stuart, Keith"

Prospective Study of Bevacizumab Plus Temozolomide in Patients With Advanced Neuroendocrine Tumors by CHAN, Jennifer A, STUART, Keith, FUCHS, Charles S, KULKE, Matthew H, EARLE, Craig C, CLARK, Jeffrey W, BHARGAVA, Pankaj, MIKSAD, Rebecca, BLASZKOWSKY, Lawrence, ENZINGER, Peter C, MEYERHARDT, Jeffrey A, HUI ZHENG

“…Both tyrosine kinase inhibitors targeting the vascular endothelial growth factor (VEGF) receptor and bevacizumab, a monoclonal antibody targeting VEGF, have…”
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Activity of Sunitinib in Patients With Advanced Neuroendocrine Tumors by KULKE, Matthew H, LENZ, Heinz-Josef, LI, Jim Z, BAUM, Charles M, FUCHS, Charles S, MEROPOL, Neal J, POSEY, James, RYAN, David P, PICUS, Joel, BERGSLAND, Emily, STUART, Keith, TYE, Lesley, XIN HUANG

“…Standard cytotoxic chemotherapy has limited efficacy in metastatic neuroendocrine tumor patients. Neuroendocrine tumors express vascular endothelial growth…”
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Phase II Study of Temozolomide and Thalidomide in Patients With Metastatic Neuroendocrine Tumors by KUIKE, Matthew H, STUART, Keith, ENZINGER, Peter C, RYAN, David P, CLARK, Jeffrey W, MUZIKANSKY, Alona, VINCITORE, Michele, MICHELINI, Ann, FUCHS, Charles S

“…Standard, intravenous chemotherapy regimens for neuroendocrine tumors have been associated with limited response rates and significant toxicity. We evaluated…”
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Phase II Study of Gemcitabine and Oxaliplatin in Combination With Bevacizumab in Patients With Advanced Hepatocellular Carcinoma by ZHU, Andrew X, BLASZKOWSKY, Lawrence S, STUART, Keith, RYAN, David P, CLARK, Jeffrey W, MUZIKANSKY, Alona, HORGAN, Kerry, SHEEHAN, Susan, HALE, Kelly E, ENZINGER, Peter C, BHARGAVA, Pankaj

“…Hepatocellular carcinoma (HCC) is a vascular tumor with poor prognosis. Given the reported activity of gemcitabine and oxaliplatin (GEMOX) in HCC and the…”
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Efficacy and safety of gemcitabine, oxaliplatin, and bevacizumab in advanced biliary-tract cancers and correlation of changes in 18-fluorodeoxyglucose PET with clinical outcome: a phase 2 study by Zhu, Andrew X, Dr, Meyerhardt, Jeffrey A, MD, Blaszkowsky, Lawrence S, MD, Kambadakone, Avinash R, MD, Muzikansky, Alona, MS, Zheng, Hui, PhD, Clark, Jeffrey W, MD, Abrams, Thomas A, MD, Chan, Jennifer A, MD, Enzinger, Peter C, MD, Bhargava, Pankaj, MD, Kwak, Eunice L, MD, Allen, Jill N, MD, Jain, Sanjay R, MD, Stuart, Keith, MD, Horgan, Kerry, BA, Sheehan, Susan, RN, Fuchs, Charles S, MD, Ryan, David P, MD, Sahani, Dushyant V, MD

“…Summary Background Previous phase 2 studies have shown antitumour activity with gemcitabine and oxaliplatin (GEMOX) in patients with advanced biliary-tract…”
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Phase 1 study of N(1),N(11)‑diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma by Goyal, Lipika, Supko, Jeffrey G, Berlin, Jordan, Blaszkowsky, Lawrence S, Carpenter, Amanda, Heuman, Douglas M, Hilderbrand, Sarah L, Stuart, Keith E, Cotler, Scott, Senzer, Neil N, Chan, Emily, Berg, Carl L, Clark, Jeffrey W, Hezel, Aram F, Ryan, David P, Zhu, Andrew X

“…N(1),N(11)-diethylnorspermine (DENSPM), a synthetic analog of the naturally occurring polyamine spermine, can induce polyamine depletion and inhibit tumor cell…”
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Radiofrequency Ablation of Hepatic Tumors: Increased Tumor Destruction with Adjuvant Liposomal Doxorubicin Therapy by Goldberg, S. Nahum, Kamel, Ihab R, Kruskal, Jonathan B, Reynolds, Kevin, Monsky, Wayne L, Stuart, Keith E, Ahmed, Muneeb, Raptopoulos, Vassilos

“…The purpose of this study was to determine whether the administration of liposomal doxorubicin before radiofrequency ablation increases coagulation more than…”
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Radiofrequency thermal ablation sharply increases intratumoral liposomal doxorubicin accumulation and tumor coagulation by AHMED, Muneeb, MONSKY, Wayne E, GIRNUN, Geoffrey, LUKYANOV, Anatoly, D'IPPOLITO, Giuseppe, KRUSKAL, Jonathan B, STUART, Keith E, TORCHILIN, Vladimir P, GOLDBERG, S. Nahum

“…Combining radiofrequency (RF) ablation with i.v. liposomal doxorubicin (Doxil) increases intratumoral doxorubicin accumulation and tumor destruction. The…”
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Adjuvant and Neoadjuvant Therapy in Curable Pancreatic Cancer by Nugent, F.W., MD, Stuart, Keith, MD

“…Pancreatic cancer is the tenth most common cancer in the United States and the fourth leading cause of cancer death. Afflicting approximately 37,000 Americans…”
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Pancreatic Adenocarcinoma in the Pregnant Patient: A Case Report and Literature Review by Kakoza, Rose M., Vollmer Jr, Charles M., Stuart, Keith E., Takoudes, Tamara, Hanto, Douglas W.

“…Pancreatic cancer is the fifth most common cause of cancer-related death in the USA. However, the antepartum diagnosis of pancreatic adenocarcinoma in the…”
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A phase II trial of gemcitabine in patients with advanced hepatocellular carcinoma by Fuchs, Charles S., Clark, Jeffrey W., Ryan, David P., Kulke, Mathew H., Kim, Haesook, Earle, Craig C., Vincitore, Michele, Mayer, Robert J., Stuart, Keith E.

“…BACKGROUND There is no effective systemic therapy for patients with hepatocellular carcinoma. A recent trial reported a moderate antitumor activity for…”
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Percutaneous tumor ablation: increased necrosis with combined radio-frequency ablation and intravenous liposomal doxorubicin in a rat breast tumor model by Goldberg, S Nahum, Girnan, Geoffrey D, Lukyanov, Anatoly N, Ahmed, Muneeb, Monsky, Wayne L, Gazelle, G Scott, Huertas, Juan Carlos, Stuart, Keith E, Jacobs, Timothy, Torchillin, Vladimir P, Halpern, Elkan F, Kruskal, Jonathan B

“…To determine whether a combination of intravenous liposomal doxorubicin and radio-frequency (RF) ablation increases tumor destruction compared with RF alone in…”
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Phase 1 study of N1,N11-diethylnorspermine (DENSPM) in patients with advanced hepatocellular carcinoma by Goyal, Lipika, Supko, Jeffrey G., Berlin, Jordan, Blaszkowsky, Lawrence S., Carpenter, Amanda, Heuman, Douglas M., Hilderbrand, Sarah L., Stuart, Keith E., Cotler, Scott, Senzer, Neil N., Chan, Emily, Berg, Carl L., Clark, Jeffrey W., Hezel, Aram F., Ryan, David P., Zhu, Andrew X.

“…Purpose N 1 , N 11 -diethylnorspermine (DENSPM), a synthetic analog of the naturally occurring polyamine spermine, can induce polyamine depletion and inhibit…”
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Liver-Directed Therapies for Metastatic Neuroendocrine Tumors by Garrot, Crain, MD, Stuart, Keith, MD

“…Neuroendocrine tumors, despite being indolent, frequently cause significant morbidity and mortality from hepatic metastatic lesions. It is possible to directly…”
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Radio-frequency ablation increases intratumoral liposomal doxorubicin accumulation in a rat breast tumor model by Monsky, Wayne L, Kruskal, Jonathan B, Lukyanov, Anatoly N, Girnun, Geoffrey D, Ahmed, Muneeb, Gazelle, G Scott, Huertas, Juan Carlos, Stuart, Keith E, Torchilin, Vladimir P, Goldberg, S Nahum

“…To determine whether intratumoral accumulation of liposomal doxorubicin or free unencapsulated doxorubicin is increased when combined with radio-frequency (RF)…”
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Liver-Directed Therapies for Colorectal Metastases by Stuart, Keith, MD

“…Hepatic metastases are frequently the primary source of symptoms and mortality in metastatic colorectal cancer. This article addresses the rationale and…”
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Percutaneous tumor ablation: increased necrosis with combined radio-frequency ablation and intratumoral doxorubicin injection in a rat breast tumor model by Goldberg, S N, Saldinger, P F, Gazelle, G S, Huertas, J C, Stuart, K E, Jacobs, T, Kruskal, J B

“…To determine whether a combination of intratumoral doxorubicin injection and radio-frequency (RF) ablation increases tumor destruction compared with RF…”
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Improvement of chemotherapy patient flow and scheduling in an outpatient oncology clinic by Liang, Bohui, Turkcan, Ayten, Ceyhan, Mehmet Erkan, Stuart, Keith

“…Due to increasing demand, the oncology clinics have been experiencing higher workloads and increasing delays in laboratory, pharmacy and chemotherapy…”
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A Phase II study of irinotecan in patients with advanced hepatocellular carcinoma by O'Reilly, Eileen M., Stuart, Keith E., Sanz‐Altamira, Pedro M., Schwartz, Gary K., Steger, Carolyn M., Raeburn, Lynn, Kemeny, Nancy E., Kelsen, David P., Saltz, Leonard B.

“…BACKGROUND Advanced hepatocellular carcinoma has a poor prognosis. In a Phase II clinical trial, two academic centers assessed irinotecan, a topoisomerase‐1…”
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Percutaneous tumor ablation: reduced tumor growth with combined radio-frequency ablation and liposomal doxorubicin in a rat breast tumor model by D'Ippolito, Giuseppe, Ahmed, Muneeb, Girnun, Geoffrey D, Stuart, Keith E, Kruskal, Jonathan B, Halpern, Elkan F, Goldberg, S Nahum

“…To determine whether combined intravenous liposomal doxorubicin and radio-frequency (RF) ablation decreases tumor growth and increases endpoint survival over…”
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