Search Results - "Stuart, K R"

Development and validation of a decision-making algorithm to guide the use of plerixafor for autologous hematopoietic stem cell mobilization by Costa, L J, Alexander, E T, Hogan, K R, Schaub, C, Fouts, T V, Stuart, R K

“…Plerixafor is an inhibitor of CXCR-4 (CXC chemokine receptor-4)/SDF (stromal cell-derived factor)-1 binding used in combination with granulocyte…”
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Maleated coupling agents for natural fibre composites by Keener, T.J, Stuart, R.K, Brown, T.K

“…Maleated coupling agents are widely used to strengthen composites containing fillers and fibre reinforcements. The established role of MaPOs results from two…”
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Epidemiology of a Daphnia-multiparasite system and its implications for the red queen by Auld, Stuart K J R, Hall, Spencer R, Duffy, Meghan A

“…The Red Queen hypothesis can explain the maintenance of host and parasite diversity. However, the Red Queen requires genetic specificity for infection risk…”
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Growth factor and patient-adapted use of plerixafor is superior to CY and growth factor for autologous hematopoietic stem cells mobilization by Costa, L J, Miller, A N, Alexander, E T, Hogan, K R, Shabbir, M, Schaub, C, Stuart, R K

“…The ideal method to mobilize autologous hematopoietic stem cells (AHSCs) in patients with lymphoma or multiple myeloma remains to be determined. The use of…”
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Growth factor plus preemptive (‘just-in-time’) plerixafor successfully mobilizes hematopoietic stem cells in multiple myeloma patients despite prior lenalidomide exposure by Costa, L J, Abbas, J, Hogan, K R, Kramer, C, McDonald, K, Butcher, C D, Littleton, A, Shoptaw, K, Kang, Y, Stuart, R K

“…Lenalidomide is associated with suboptimal autologous hematopoietic stem cell (AHSC) mobilization. We hypothesized that growth factor plus preemptive…”
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Environmental variation causes different (co) evolutionary routes to the same adaptive destination across parasite populations by Auld, Stuart K. J. R., Brand, June

“…Epidemics are engines for host‐parasite coevolution, where parasite adaptation to hosts drives reciprocal adaptation in host populations. A key challenge is to…”
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Radiation‐mediated supply of genetic variation outweighs the effects of selection and drift in Chernobyl Daphnia populations by Goodman, Jessica, Brand, June, Laptev, Gennady, Auld, Stuart K. J. R.

“…Populations experiencing varying levels of ionizing radiation provide an excellent opportunity to study the fundamental drivers of evolution. Radiation can…”
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Fitness consequences of immune responses: strengthening the empirical framework for ecoimmunology by Graham, Andrea L, Shuker, David M, Pollitt, Laura C, Auld, Stuart K.J.R, Wilson, Alastair J, Little, Tom J

“…1. Ecoimmunologists aim to understand the costs, benefits, and net fitness consequences of different strategies for immune defense. 2. Measuring the fitness…”
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Parasite transmission in a natural multihost–multiparasite community by Auld, Stuart K. J. R., Searle, Catherine L., Duffy, Meghan A.

“…Understanding the transmission and dynamics of infectious diseases in natural communities requires understanding the extent to which the ecology, evolution and…”
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Predator‐induced shape plasticity in Daphnia pulex by Paplauskas, Sam, Morton, Oscar, Hunt, Mollie, Courage, Ashleigh, Swanney, Stephanie, Dennis, Stuart R., Becker, Dörthe, Auld, Stuart K. J. R., Beckerman, Andrew P.

“…All animals and plants respond to changes in the environment during their life cycle. This flexibility is known as phenotypic plasticity and allows organisms…”
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Ecology directs host–parasite coevolutionary trajectories across Daphnia–microparasite populations by Paplauskas, Sam, Brand, June, Auld, Stuart K. J. R.

“…Host–parasite interactions often fuel coevolutionary change. However, parasitism is one of a myriad of possible ecological interactions in nature. Biotic (for…”
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Variation in chronic radiation exposure does not drive life history divergence among Daphnia populations across the Chernobyl Exclusion Zone by Goodman, Jessica, Copplestone, David, Laptev, Gennady V., Gashchak, Sergey, Auld, Stuart K. J. R.

“…Ionizing radiation is a mutagen with known negative impacts on individual fitness. However, much less is known about how these individual fitness effects…”
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Adjuvant Active Specific Immunotherapy for Stage II and III Colon Cancer With an Autologous Tumor Cell Vaccine: Eastern Cooperative Oncology Group Study E5283 by HARRIS, J. E, RYAN, L, HOOVER, H. C, STUART, R. K, OKEN, M. M, BENSON, A. B, MANSOUR, E, HALLER, D. G, MANOLA, J, HANNA, M. G

“…A randomized phase III clinical trial of adjuvant active specific immunotherapy (ASI) with an autologous tumor cell-bacillus Calmette-Guérin (BCG) vaccine was…”
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Rapid change in parasite infection traits over the course of an epidemic in a wild host–parasite population by Auld, Stuart K. J. R., Wilson, Philip J., Little, Tom J.

“…By combining a field study with controlled laboratory experimentation, we examined how infection traits of the sterilizing bacterium, Pasteuria ramosa, changed…”
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THE CELLULAR IMMUNE RESPONSE OF DAPHNIA MAGNA UNDER HOST-PARASITE GENETIC VARIATION AND VARIATION IN INITIAL DOSE by Auld, Stuart K. J. R., Edel, Kai H., Little, Tom J.

“…In invertebrate—parasite systems, the likelihood of infection following parasite exposure is often dependent on the specific combination of host and parasite…”
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Immunobiology of allogeneic peripheral blood mononuclear cells mobilized with granulocyte-colony stimulating factor by GYGER, M, STUART, R. K, PERREAULT, C

“…The use of mobilized peripheral blood (PB) stem cells for autologous transplantation initially generated much enthusiasm because of enhanced engraftment in…”
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Elevated haemocyte number is associated with infection and low fitness potential in wild Daphnia magna by Auld, Stuart K. J. R., Graham, Andrea L., Wilson, Philip J., Little, Tom J.

“…1. Immune activity may be a cause of resistance to parasites, but it can also be a consequence of infection. Thus, the adaptive significance of an immune…”
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Effects of juvenile host density and food availability on adult immune response, parasite resistance and virulence in a Daphnia-parasite system by Schoebel, Corine N, Auld, Stuart K J R, Spaak, Piet, Little, Tom J

“…Host density can increase infection rates and reduce host fitness as increasing population density enhances the risk of becoming infected either through…”
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The bacterial parasite Pasteuria ramosa is not killed if it fails to infect: implications for coevolution by King, Kayla C., Auld, Stuart K. J. R., Wilson, Philip J., James, Janna, Little, Tom J.

“…Strong selection on parasites, as well as on hosts, is crucial for fueling coevolutionary dynamics. Selection will be especially strong if parasites that…”
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P515: LOWER‐INTENSITY CPX‐351 + VENETOCLAX FOR PATIENTS WITH NEWLY DIAGNOSED ACUTE MYELOID LEUKEMIA WHO ARE UNFIT FOR INTENSIVE CHEMOTHERAPY by Uy, G. L., Pullarkat, V. A., Baratam, P., Stuart, R. K., Walter, R. B., Winer, E. S., Faderl, S., Chandrasekaran, V., Wang, Q., Chakravarthy, D., Cheung, R. S., Lin, T. L.

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