Search Results - "Strych, Lukáš"

Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense by Krejčová, Gabriela, Danielová, Adéla, Nedbalová, Pavla, Kazek, Michalina, Strych, Lukáš, Chawla, Geetanjali, Tennessen, Jason M, Lieskovská, Jaroslava, Jindra, Marek, Doležal, Tomáš, Bajgar, Adam

“…Macrophage-mediated phagocytosis and cytokine production represent the front lines of resistance to bacterial invaders. A key feature of this pro-inflammatory…”
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Glucose and trehalose metabolism through the cyclic pentose phosphate pathway shapes pathogen resistance and host protection in Drosophila by Kazek, Michalina, Chodáková, Lenka, Lehr, Katharina, Strych, Lukáš, Nedbalová, Pavla, McMullen, Ellen, Bajgar, Adam, Opekar, Stanislav, Šimek, Petr, Moos, Martin, Doležal, Tomáš

“…Activation of immune cells requires the remodeling of cell metabolism in order to support immune function. We study these metabolic changes through the…”
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Targeted long-read sequencing identified a causal structural variant in X-linked nephrogenic diabetes insipidus by Strych, Lukáš, Černá, Monika, Hejnalová, Markéta, Zavoral, Tomáš, Komrsková, Pavla, Tejcová, Jitka, Bitar, Ibrahim, Sládková, Eva, Sýkora, Josef, Šubrt, Ivan

“…X-linked nephrogenic diabetes insipidus (NDI) is a rare genetic renal disease caused by pathogenic variants in the AVPR2 gene. Single nucleotide variants and…”
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A recurrent synonymous L1CAM variant in a fetus with hydrocephalus by Šubrt, Ivan, Zavoral, Tomáš, Strych, Lukáš, Černá, Monika, Hejnalová, Markéta, Komrsková, Pavla, Tejcová, Jitka

“…We report the case of a hydrocephalic fetus in which clinical exome sequencing revealed a recurrent synonymous variant of unknown significance, c.453G>T, in…”
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JAK/STAT mediated insulin resistance in muscles is essential for effective immune response by McMullen, Ellen, Strych, Lukas, Chodakova, Lenka, Krebs, Amber, Dolezal, Tomas

“…The metabolically demanding nature of immune response requires nutrients to be preferentially directed towards the immune system at the expense of peripheral…”
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