Search Results - "Strutynska, N A"

Stimulation of the endogenous hydrogen sulfide synthesis suppresses oxidative-nitrosative stress and restores endothelial-dependent vasorelaxation in old rats by Mys, L A, Strutynska, N A, Goshovska, Y V, Sagach, V F

“…Hydrogen sulfide (H S) is an endogenous gas transmitter with profound effects on the cardiovascular system. We hypothesized that stimulation of H S synthesis…”
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MITOCHONDRIAL DYSFUNCTION IN THE AGING HEART IS ACCOMPANIED BY CONSTITUTIVE NO-SYNTHASES UNCOUPLING ON THE BACKGROUND OF OXIDATIVE AND NITROSATIVE STRESS by Strutynska, N A, Kotsiuruba, A V, Budko, A Yu, Mys, L A, Sagach, V F

“…We investigated the sensitivity of mitochondrial permeability transition pore (MPTP) opening to its inductor calcium, as well as indicators of oxidative and…”
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Increase in the sensitivity of the mitochondrial permeability transition pore opening to Ca2+ in heart of spontaneous hypertensive rat by Strutyns'ka, N A, Dorofeieva, N O, Vavilova, H L, Sahach, V F

“…In experiments vitro on the mitochondria isolated from adult and spontaneous hypertensive rat hearts, we studied the sensitivity of the mitochondrial…”
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Stimulation of the endogenous hydrogen sulfide synthesis restores constitutive nitric oxide synthesis and endothelium-dependent vasodilation in old rats by Mys, LA, Strutynska, NA, Luchkova, AY, Sagach, VF

“…Abstract Funding Acknowledgements Type of funding sources: None. Introduction Hydrogen sulfide (H2S) is a gas transmitter of endogenous origin, which has an…”
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Regular exercise increases H2S levels in mitochondria and cardiac tissue, enhances genes expression of H2S-synthesizing enzymes and prevents mitochondrial swelling by Luchkova, AY, Mys, LA, Strutynska, NA, Sagach, VF

“…Abstract Funding Acknowledgements Type of funding sources: None. Introduction It is known that regular exercise is important and very useful for the…”
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PYRIDOXAL-5-PHOSPHATE RESTORES HYDROGEN SULFIDE SYNTHES AND REDOX STATE OF HEART AND BLOOD VESSELS TISSUE IN OLD ANIMALS by Mys, L A, Budko, A Yu, Strutynska, N A, Sagach, V F

“…It was shown the alterations in hydrogen sulfide (H(2)S) metabolism and the development of oxidative and nitrozative stress in cardiovascular system by aging…”
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CA²⁺ ACCUMULATION IN ISOLATED RAT HEART MITOCHONDRIA UNDER MAINTENANCE OF MITOCHONDRIAL POTENTIAL by Budko, A Yu, Strutynska, N A, Okhay, I Yu, Semenykhina, O M, Sagach, V F

“…It is known that mitochondria can accumulate calcium, which regulates energy metabolism and cell death. About 90% of energy of cardiomyocytes is synthesized in…”
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Hydrogen sulfide inhibits Ca(2+)-induced mitochondrial permeability transition pore opening in spontaneously hypertensive rats by Strutyns'ka, N A, Dorofeieva, N O, Vavilova, H L, Sahach, V F

“…In experiments in vivo and in vitro on the mitochondria isolated from the control and spontaneously hypertensive rats (SHR) hearts, we studied the effects of a…”
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Influence of flocalin on development of apoptosis and necrosis at anoxia-reoxygenation of culture rats neonatal cardiomyocytes by Strutyns'kyĭ, R B, Nagibin, V S, Strutyns'ka, N A, Ianchiĭ, O R, Moĭbenko, O O

“…The influence of the new cardioprotector flocalin was investigated on the culture of rat's neonatal cardiomyocytes during anoxia-reoxygenation modelling. The…”
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The influence of activation of the ATP-sensitive potassium channels by flocalin on the function of the cardiovascular system by Strutyns'kyĭ, R B, Rovenets', R A, Strutyns'ka, N A, Neshcheret, O P, Moĭbenko, O O

“…In experiments on the anaesthetized dogs the influence of a new fluorine-containing opener of ATP-sensitive potassium (K(ATP)) channels flocalin on the…”
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Biochemical mechanisms of the cardioprotective effect of the K(ATP) channels opener flocalin (medicinal form) in ischemia-reperfusion of myocardium by Strutyns'kyĭ, R B, Kotsiuruba, A V, Rovenets', R A, Strutyns'ka, N A, Iagupols'kyĭ, Iu L, Sagach, V F, Moĭbenko, O O

“…In experiments on the anaesthetized dogs with modeling of experimental ischemia (90 min) and reperfusion (180 min) of myocardium it was investigated changes of…”
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Effect of hydrogen sulfide donor NaHs on the functional state of the respiratory chain of the rat heart mitochondria by Semenykhina, O M, Strutyns'ka, N A, Bud'ko, A Iu, Vavilova, H L, Sahach, V F

“…In experiments on mitochondria isolated from the heart tissue of adult rats we studied the effects of a donor of hydrogen sulfide, NaHS, on the respiratory…”
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New fluorine-containing openers of ATP-sensitive potassium channels flokalin and tioflokalin inhibit calcium-induced mitochondrial pore opening in rat hearts by Strutyns'ka, N A, Strutyns'kyĭ, R B, Chorna, S V, Semenykhina, O M, Mys', L A, Moĭbenko, O O, Sahach, V F

“…In experiments in vitro on the mitochondria isolated from the rat's heart we studied the effects of the openers of ATP-sensitive potassium channels…”
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Hydrogen sulfide inhibits Ca(2+)-induced mitochondrial permeability transition pore opening in adult and old rat heart by Strutyns'ka, N A, Semenykhina, O M, Chorna, S V, Vavilova, H L, Sahach, V F

“…In experiments in vivo and in vitro on the mitochondria isolated from adult and old rat hearts, we studied the effects of a donor of hydrogen sulfide (H2S),…”
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Increased expression of voltage-dependent anion channel and adenine nucleotide translocase and the sensitivity of calcium-induced mitochondrial permeability transition opening pore in the old rat heart by Chorna, S V, Dosenko, V Ie, Strutyns'ka, N A, Vavilova, H L, Sahach, V F

“…We investigated mRNA and protein expression of voltage-dependent anion channel (VDAC), mRNA adenine nucleotide translocase (ANT) as well as the sensitivity of…”
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Expression of UCP3 and the sensitivity of mitochondrial permeability transition pore opening to Ca2+ in old rat heart under activation of biosynthesis of coenzyme Q by Strutyns'ka, N A, Timoshchuk, S V, Vavilova, H L, Kotsiuruba, A V, Sahach, V F

“…The expression of mitochondrial uncoupling protein 3 (UCP3), as well as the sensitivity of mitochondrial permeability transition pore opening (MPTP) to Ca2+…”
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Cardioprotective action of coenzyme Q in conditions of its endogenous synthesis activation in cardiac ischemia-reperfusion in old rats by Timoshchuk, S V, Vavilova, H L, Strutyns'ka, N A, Talanov, S A, Petukhov, D M, Kuchmenko, O B, Donchenko, H V, Sahach, V F

“…The changes of functional state isolated by Lanhendorf old rat hearts with low content of ubiqinone--coenzyme Q (CoQ) under activation of it endogenous…”
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In vivo effect of precursors of ubiquinone biosynthesis on sensitivity of mitochondrial permeability transition pore in the heart of old rats by Timoshchuk, S V, Vavilova, H L, Strutyns'ka, N A, Kuchmenko, O B, Petukhov, D M, Donchenko, H V, Sahach, V F

“…This research work is devoted to study of the sensitivity of mitochondrial permeability transition pore (MPTP) opening to its inductors--ions Ca2+ (10(-4)…”
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Sensitivity of phenylarsineoxide-induced mitochondrial permeability transition pore opening in the heart of old rats during intermittent hypoxic training by Rudyk, O V, Vavilova, H L, Strutyns'ka, N A, Kotsiuruba, A V, Sahach, V F

“…We studied the sensitivity of mitochondrial permeability transition pore (MPTP) opening to its inductor-phenylarsineoxide (PAO) in adult (6 months), old rat…”
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Aging-related increase of sensitivity of the mitochondrial permeability transition pore to inductors in the rat heart by Sahach, V F, Vavilova, H L, Strutyns'ka, N A, Rudyk, O V

“…An age-related increase in the sensitivity of the mitochondrial permeability transition pore (MPTP) to inductors of it's opening, Ca2+ ions and…”
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