Search Results - "Strunin, Dmytro"
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Most anti-BrdU antibodies react with 2'-deoxy-5-ethynyluridine -- the method for the effective suppression of this cross-reactivity
Published in PloS one (18-12-2012)“…5-Bromo-2'-deoxyuridine (BrdU) and 2'-deoxy-5-ethynyluridine (EdU) are widely used as markers of replicated DNA. While BrdU is detected using antibodies, the…”
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2
A fatal combination: a thymidylate synthase inhibitor with DNA damaging activity
Published in PloS one (11-02-2015)“…2'-Deoxy-5-ethynyluridine (EdU) has been previously shown to be a cell poison whose toxicity depends on the particular cell line. The reason is not known. Our…”
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3
Atomic scissors: a new method of tracking the 5-bromo-2'-deoxyuridine-labeled DNA in situ
Published in PloS one (26-12-2012)“…A new method of the light microscopy detection of BrdU-labeled DNA in situ is described. It is based on the oxidative attack at the deoxyribose moiety by…”
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4
A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA
Published in PloS one (18-06-2013)“…The study describes the method of a sensitive detection of double-stranded DNA molecules in situ. It is based on the oxidative attack on the deoxyribose moiety…”
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5
Hepatitis B Core Protein Is Post-Translationally Modified through K29-Linked Ubiquitination
Published in Cells (Basel, Switzerland) (26-11-2020)“…Hepatitis B virus (HBV) core protein (HBc) plays many roles in the HBV life cycle, such as regulation of transcription, RNA encapsidation, reverse…”
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A Comparison of Protein and mRNA Expression during Development of the Soil Dwelling Prokaryote (S. coelicolor)
Published in Proteomics (Weinheim) (01-12-2020)Get full text
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A Comparison of Protein and mRNA Expression during Development of the Soil Dwelling Prokaryote (S. coelicolor)
Published in Proteomics (Weinheim) (01-07-2020)“…In this paper, correlation analysis of protein and mRNA levels in the soil dwelling bacteria Streptomyces coelicolor (S. coelicolor M145) is presented during…”
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Rational Design of Novel Highly Potent and Selective Phosphatidylinositol 4‑Kinase IIIβ (PI4KB) Inhibitors as Broad-Spectrum Antiviral Agents and Tools for Chemical Biology
Published in Journal of medicinal chemistry (12-01-2017)“…Phosphatidylinositol 4-kinase IIIβ (PI4KB) is indispensable for the replication of various positive-sense single stranded RNA viruses, which hijack this…”
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Highly Selective Phosphatidylinositol 4‑Kinase IIIβ Inhibitors and Structural Insight into Their Mode of Action
Published in Journal of medicinal chemistry (14-05-2015)“…Phosphatidylinositol 4-kinase IIIβ is a cellular lipid kinase pivotal to pathogenesis of various RNA viruses. These viruses hijack the enzyme in order to…”
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10
Purine analogs as phosphatidylinositol 4-kinase IIIβ inhibitors
Published in Bioorganic & medicinal chemistry letters (01-06-2016)“…[Display omitted] We report on an extensive structure–activity relationship study of novel PI4K IIIβ inhibitors. The purine derivative of the potent screening…”
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11
Impaired human immunodeficiency virus type 1 replicative fitness in atypical viremic non-progressor individuals
Published in AIDS research and therapy (20-03-2017)“…Progression rates from initial HIV-1 infection to advanced AIDS vary significantly among infected individuals. A distinct subgroup of HIV-1-infected…”
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A New Method of the Visualization of the Double-Stranded Mitochondrial and Nuclear DNA. e66864
Published in PloS one (01-06-2013)“…The study describes the method of a sensitive detection of double-stranded DNA molecules in situ. It is based on the oxidative attack on the deoxyribose moiety…”
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13
A Fatal Combination: A Thymidylate Synthase Inhibitor with DNA Damaging Activity: e0117459
Published in PloS one (01-02-2015)“…2'-deoxy-5-ethynyluridine (EdU) has been previously shown to be a cell poison whose toxicity depends on the particular cell line. The reason is not known. Our…”
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Journal Article