Search Results - "Strungs, Erik G"
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Cryoinjury models of the adult and neonatal mouse heart for studies of scarring and regeneration
Published in Methods in molecular biology (Clifton, N.J.) (01-01-2013)“…A major limitation in studies of the injured heart is animal-to-animal variability in wound size resulting from commonly used techniques such as left anterior…”
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The conformational signature of β-arrestin2 predicts its trafficking and signalling functions
Published in Nature (London) (31-03-2016)“…A series of intramolecular fluorescent FlAsH BRET reporters is used to monitor conformational changes in β-arrestin2 following activation of seven…”
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Probing Arrestin Function Using Intramolecular FlAsH-BRET Biosensors
Published in Methods in molecular biology (Clifton, N.J.) (2019)“…Information contained in the structure of extracellular ligands is transmitted across the cell membrane through allosterically induced changes in G…”
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Arrestin-dependent activation of ERK and Src family kinases
Published in Handbook of experimental pharmacology (2014)“…The four members of the mammalian arrestin family, two visual and two nonvisual, share the property of stimulus-dependent docking to G protein-coupled…”
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Angiotensin II receptors and peritoneal dialysis-induced peritoneal fibrosis
Published in The international journal of biochemistry & cell biology (01-08-2016)“…The vasoactive hormone angiotensin II initiates its major hemodynamic effects through interaction with AT1 receptors, a member of the class of G…”
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The β-Arrestin Pathway-selective Type 1A Angiotensin Receptor (AT1A) Agonist [Sar1,Ile4,Ile8]Angiotensin II Regulates a Robust G Protein-independent Signaling Network
Published in The Journal of biological chemistry (03-06-2011)“…The angiotensin II peptide analog [Sar1,Ile4,Ile8]AngII (SII) is a biased AT1A receptor agonist that stimulates receptor phosphorylation, β-arrestin…”
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The Mechanism of Cardiac Failure in Experimental Myocardial Infarction
Published in Journal of cardiac failure (01-08-2008)Get full text
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Ligand‐specific patterns of PTH1R and arrestin3 internalization and trafficking define a novel form of ligand “bias”
Published in The FASEB journal (01-04-2018)“…The type 1 parathyroid hormone receptor (PTH1R) couples to Gs, Gq/11, and Gi/o family heterotrimeric G proteins and binds arrestins, which mediate receptor…”
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Ligand‐specific patterns of PTH 1 R and arrestin3 internalization and trafficking define a novel form of ligand “bias”
Published in The FASEB journal (01-04-2018)“…Abstract only The type 1 parathyroid hormone receptor (PTH 1 R) couples to G s , G q/11 , and G i/o family heterotrimeric G proteins and binds arrestins, which…”
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The conformational signature of [beta]-arrestin2 predicts its trafficking and signalling functions
Published in Nature (London) (31-03-2016)“…A series of intramolecular fluorescent FlAsH BRET reporters is used to monitor conformational changes in [beta]-arrestin2 following activation of seven…”
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11
The conformational signature of arrestin3 predicts its trafficking and signaling functions
Published in Nature (London) (23-03-2016)“…Arrestins are cytosolic proteins that regulate G protein-coupled receptor (GPCR) desensitization, internalization, trafficking, and signaling 1 , 2 . Arrestin…”
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