Search Results - "Struhalla, Marc"
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Optical tweezers to study single Protein A/Immunoglobulin G interactions at varying conditions
Published in European biophysics journal (01-07-2008)“…Optical tweezers (OT) are ideally suited to study the interaction of single receptor-ligand bonds. Here we introduce a newly developed assay using OT to…”
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Kinetics of TmHU binding to DNA as observed by optical tweezers
Published in Microscopy research and technique (01-11-2007)“…The kinetics of binding for the histone‐like protein TmHU (from Thermotoga maritima) to DNA is analyzed on a single molecule level by use of optical tweezers…”
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Addressing the Challenge of Changing the Specificity of RNase T1 with Rational and Evolutionary Approaches
Published in Chembiochem : a European journal of chemical biology (06-02-2004)“…Although ribonuclease T1 (RNase T1) is one of the best-characterized proteins with respect to structure and enzymatic action, numerous attempts at altering the…”
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RNase T1 Variant RV Cleaves Single-Stranded RNA after Purines Due to Specific Recognition by the Asn46 Side Chain Amide
Published in Biochemistry (Easton) (16-03-2004)“…Attempts to alter the guanine specificity of ribonuclease T1 (RNase T1) by rational or random mutagenesis have failed so far. The RNase T1 variant RV…”
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Aptamers that recognize the lipid moiety of the antibiotic moenomycin A
Published in Biological chemistry (01-10-2003)“…Moenomycin A is an amphiphilic phosphoglycolipid antibiotic that interferes with the transglycosylation step in peptidoglycan biosynthesis. The antibiotic…”
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