Search Results - "Struck, Travis J."

The impact of genome-wide association studies on biomedical research publications by Struck, Travis J, Mannakee, Brian K, Gutenkunst, Ryan N

“…The past decade has seen major investment in genome-wide association studies (GWAS). Among the many goals of GWAS, a major one is to identify and motivate…”
Get full text

Computationally efficient demographic history inference from allele frequencies with supervised machine learning by Tran, Linh N, Sun, Connie K, Struck, Travis J, Sajan, Mathews, Gutenkunst, Ryan N

“…Inferring past demographic history of natural populations from genomic data is of central concern in many studies across research fields. Previously, our group…”
Get full text

Demes: a standard format for demographic models by Gower, Graham, Ragsdale, Aaron P, Bisschop, Gertjan, Gutenkunst, Ryan N, Hartfield, Matthew, Noskova, Ekaterina, Schiffels, Stephan, Struck, Travis J, Kelleher, Jerome, Thornton, Kevin R

“…Understanding the demographic history of populations is a key goal in population genetics, and with improving methods and data, ever more complex models are…”
Get full text

The genomic origins of the world’s first farmers by Marchi, Nina, Winkelbach, Laura, Schulz, Ilektra, Brami, Maxime, Hofmanová, Zuzana, Blöcher, Jens, Reyna-Blanco, Carlos S., Diekmann, Yoan, Thiéry, Alexandre, Kapopoulou, Adamandia, Link, Vivian, Piuz, Valérie, Kreutzer, Susanne, Figarska, Sylwia M., Ganiatsou, Elissavet, Pukaj, Albert, Struck, Travis J., Gutenkunst, Ryan N., Karul, Necmi, Gerritsen, Fokke, Pechtl, Joachim, Peters, Joris, Zeeb-Lanz, Andrea, Lenneis, Eva, Teschler-Nicola, Maria, Triantaphyllou, Sevasti, Stefanović, Sofija, Papageorgopoulou, Christina, Wegmann, Daniel, Burger, Joachim, Excoffier, Laurent

“…The precise genetic origins of the first Neolithic farming populations in Europe and Southwest Asia, as well as the processes and the timing of their…”
Get full text

Inferring Genome-Wide Correlations of Mutation Fitness Effects between Populations by Huang, Xin, Fortier, Alyssa Lyn, Coffman, Alec J, Struck, Travis J, Irby, Megan N, James, Jennifer E, León-Burguete, José E, Ragsdale, Aaron P, Gutenkunst, Ryan N

“…Abstract The effect of a mutation on fitness may differ between populations depending on environmental and genetic context, but little is known about the…”
Get full text

Triallelic Population Genomics for Inferring Correlated Fitness Effects of Same Site Nonsynonymous Mutations by Ragsdale, Aaron P, Coffman, Alec J, Hsieh, PingHsun, Struck, Travis J, Gutenkunst, Ryan N

“…The distribution of mutational effects on fitness is central to evolutionary genetics. Typical univariate distributions, however, cannot model the effects of…”
Get full text

Testing whether metazoan tyrosine loss was driven by selection against promiscuous phosphorylation by Pandya, Siddharth, Struck, Travis J, Mannakee, Brian K, Paniscus, Mary, Gutenkunst, Ryan N

“…Protein tyrosine phosphorylation is a key regulatory modification in metazoans, and the corresponding kinase enzymes have diversified dramatically. This…”
Get full text

A community-maintained standard library of population genetic models by Adrion, Jeffrey R, Cole, Christopher B, Dukler, Noah, Galloway, Jared G, Gladstein, Ariella L, Gower, Graham, Kyriazis, Christopher C, Ragsdale, Aaron P, Tsambos, Georgia, Baumdicker, Franz, Carlson, Jedidiah, Cartwright, Reed A, Durvasula, Arun, Gronau, Ilan, Kim, Bernard Y, McKenzie, Patrick, Messer, Philipp W, Noskova, Ekaterina, Ortega-Del Vecchyo, Diego, Racimo, Fernando, Struck, Travis J, Gravel, Simon, Gutenkunst, Ryan N, Lohmueller, Kirk E, Ralph, Peter L, Schrider, Daniel R, Siepel, Adam, Kelleher, Jerome, Kern, Andrew D

“…The explosion in population genomic data demands ever more complex modes of analysis, and increasingly, these analyses depend on sophisticated simulations…”
Get full text