Search Results - "Strouse, J F"
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Renin inhibitors containing C-termini derived from mercaptoheterocycles
Published in Journal of medicinal chemistry (01-05-1992)“…A series of transition-state analogues having heterocyclythio C-termini has been synthesized and evaluated for inhibition of human renin. Addition of…”
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Inhibitors of human renin with C-termini derived from amides and esters of .alpha.-mercaptoalkanoic acids
Published in Journal of medicinal chemistry (01-07-1992)“…New transition-state analogues bearing C-termini derived from alpha-mercaptoalkanoic acids, esters, and amides were prepared and evaluated as inhibitors of…”
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Acute hypotensive responses to peptide inhibitors of renin in conscious monkeys: an effect on blood pressure independent of plasma renin inhibition
Published in Journal of hypertension (01-03-1990)“…In order to investigate the hypotensive mechanisms of action of peptide renin inhibitors, blood pressure responses to five renin inhibitors were compared with…”
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Renin inhibitors containing conformationally restricted P1-P1' dipeptide mimetics
Published in Journal of medicinal chemistry (01-03-1991)“…A series of renin inhibitors containing lactam-bridged P1-P1' dipeptide mimetics based on the ACHPA (4(S)-amino-5-cyclohexyl-3(S)-hydroxypentanoic acid) design…”
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Renin inhibitors containing conformationally restricted P1P1' dipeptide mimetics
Published in Journal of medicinal chemistry (1991)Get full text
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