Search Results - "Stroun, Maurice"
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The virtosome-a novel cytosolic informative entity and intercellular messenger
Published in Cell biochemistry and function (01-10-2010)“…Studies on a range of prokaryote and eukaryote cells and tissues have shown that a newly synthesized DNA/RNA–lipoprotein complex is released in a regulated…”
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Cell-Free Nucleic Acids Circulating in the Plasma of Colorectal Cancer Patients Induce the Oncogenic Transformation of Susceptible Cultured Cells
Published in Cancer research (Chicago, Ill.) (15-01-2010)“…It has been proposed that cell-free nucleic acids in the plasma participate in tumorigenesis and the development of metastases via transfection-like uptake of…”
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A Preliminary Study of the Action of Virtosomes from Non-dividing Cells on Tumour Cell Replication in vitro and in vivo
Published in Anti-cancer agents in medicinal chemistry (01-01-2017)“…A DNA-RNA-lipoprotein complex, termed as virtosome, is released spontaneously from healthy human, other mammalian, avian, amphibian and plant cells in a…”
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Circulating nucleic acids in plasma and serum as a noninvasive investigation for cancer: Time for large‐scale clinical studies?
Published in International journal of cancer (10-01-2003)Get full text
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Microsatellite alterations in serum DNA of head and neck cancer patients
Published in Nature medicine (01-09-1996)“…Microsatellite DNA alterations are an integral part of neoplastic progression and are valuable as clonal markers for the detection of human cancers. Moreover,…”
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The Origin and Mechanism of Circulating DNA
Published in Annals of the New York Academy of Sciences (01-04-2000)Get full text
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Telomerase RNA as a Detection Marker in the Serum of Breast Cancer Patients
Published in Clinical cancer research (01-10-2000)“…Tumor-derived circulating DNA has been found in the plasma of cancer patients. Alterations include decreased strand stability, mutations of oncogenes or of…”
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Microsatellite alterations in plasma DNA of small cell lung cancer patients
Published in Nature medicine (01-09-1996)“…Microsatellite instability is an important characteristic of many tumor types especially those associated with hereditary non-polyposis colorectal carcinoma…”
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Detecting Tumor-related Alterations in Plasma or Serum DNA of Patients Diagnosed with Breast Cancer
Published in Clinical cancer research (01-09-1999)“…Chromosomal abnormalities are associated with the development of breast cancer, and widespread allelic loss or imbalance is frequently found in tumor tissues…”
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Circulating nucleic acids and evolution
Published in Expert opinion on biological therapy (01-06-2012)“…J.B. Lamarck in 1809 was the first to present a theory of evolution. He proposed it was due to the adaptation of species to environmental changes, this…”
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Metabolic DNA as the Origin of Spontaneously Released DNA?
Published in Annals of the New York Academy of Sciences (01-08-2008)“…A DNA fraction is spontaneously released from living, but not dead or dying, human, other mammalian, avian, amphibian, plant, and prokaryote cells. The…”
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Prehistory of the notion of circulating nucleic acids in plasma/serum (CNAPS): birth of a hypothesis
Published in Annals of the New York Academy of Sciences (01-09-2006)“…In the late 50s and early 60s of the last century, a theoretical fight was taking place between Western and Russian scientists about the theory explaining the…”
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Non-dividing Cell Virtosomes Affect In Vitro and In Vivo Tumour Cell Replication
Published in Advances in experimental medicine and biology (2016)“…In vitro studies of partially purified virtosomes from rat liver showed inhibition of cell multiplication in four normal and two tumour cell lines. In vivo,…”
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Immunological Aspects of Circulating DNA
Published in Annals of the New York Academy of Sciences (01-09-2006)“…: Nude mice were injected with DNA released by T lymphocytes previously exposed to inactivated herpes symplex type 1 or polio viruses. The serum of these mice…”
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Prehistory of the Notion of Circulating Nucleic Acids in Plasma/Serum (CNAPS)
Published in Annals of the New York Academy of Sciences (01-09-2006)“…: In the late 50s and early 60s of the last century, a theoretical fight was taking place between Western and Russian scientists about the theory explaining…”
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The protein composition of virtosomes isolated from non stimulated and stimulated lymphocytes
Published in Current opinion in biotechnology (01-07-2013)Get full text
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Detection of circulating tumour DNA in the blood (plasma/serum) of cancer patients
Published in Cancer and metastasis reviews (1999)“…Small amounts of free DNA circulate in both healthy and diseased human plasma/serum, and increased concentrations of DNA are present in the plasma of cancer…”
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Alu repeat sequences are present in increased proportions compared to a unique gene in plasma/serum DNA: evidence for a preferential release from viable cells?
Published in Annals of the New York Academy of Sciences (01-09-2001)“…Small amounts of DNA circulate freely in plasma or serum, but the mechanism of release is not known. To determine if DNA is actively excreted from viable…”
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Quantification of free total plasma DNA and minimal residual disease detection in the plasma of children with acute lymphoblastic leukemia
Published in Annals of hematology (01-09-2009)“…The analysis of total plasma DNA and the monitoring of leukemic clone-specific immunoglobulin and/or T-cell receptor gene rearrangements for the evaluation of…”
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