Search Results - "Strong, Sarah A."

Discovery of potent and novel S-nitrosoglutathione reductase inhibitors devoid of cytochrome P450 activities by Sun, Xicheng, Qiu, Jian, Strong, Sarah A., Green, Louis S., Wasley, Jan W.F., Blonder, Joan P., Colagiovanni, Dorothy B., Mutka, Sarah C., Stout, Adam M., Richards, Jane P., Rosenthal, Gary J.

“…The pyrrole based N6022 was recently identified as a potent, selective, reversible, and efficacious S-nitrosoglutathione reductase (GSNOR) inhibitor and is…”
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Discovery of S-Nitrosoglutathione Reductase Inhibitors: Potential Agents for the Treatment of Asthma and Other Inflammatory Diseases by Sun, Xicheng, Wasley, Jan W. F, Qiu, Jian, Blonder, Joan P, Stout, Adam M, Green, Louis S, Strong, Sarah A, Colagiovanni, Dorothy B, Richards, Jane P, Mutka, Sarah C, Chun, Lawrence, Rosenthal, Gary J

“…S-Nitrosoglutathione reductase (GSNOR) regulates S-nitrosothiols (SNOs) and nitric oxide (NO) in vivo through catabolism of S-nitrosoglutathione (GSNO). GSNOR…”
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Structure–activity relationship of pyrrole based S-nitrosoglutathione reductase inhibitors: Carboxamide modification by Sun, Xicheng, Qiu, Jian, Strong, Sarah A., Green, Louis S., Wasley, Jan W.F., Blonder, Joan P., Colagiovanni, Dorothy B., Stout, Adam M., Mutka, Sarah C., Richards, Jane P., Rosenthal, Gary J.

“…The enzyme S-nitrosoglutathione reductase (GSNOR) is a member of the alcohol dehydrogenase family (ADH) that regulates the levels of S-nitrosothiols (SNOs)…”
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Structure–activity relationships of pyrrole based S-nitrosoglutathione reductase inhibitors: Pyrrole regioisomers and propionic acid replacement by Sun, Xicheng, Qiu, Jian, Strong, Sarah A., Green, Louis S., Wasley, Jan W.F., Colagiovanni, Dorothy B., Mutka, Sarah C., Blonder, Joan P., Stout, Adam M., Richards, Jane P., Chun, Lawrence, Rosenthal, Gary J.

“…S-Nitrosoglutathione reductase (GSNOR) is a member of the alcohol dehydrogenase family (ADH) that regulates the levels of S-nitrosothiols (SNOs) through…”
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