Search Results - "Strom, Molly"

Awake dynamics and brain-wide direct inputs of hypothalamic MCH and orexin networks by González, J. Antonio, Iordanidou, Panagiota, Strom, Molly, Adamantidis, Antoine, Burdakov, Denis

“…The lateral hypothalamus (LH) controls energy balance. LH melanin-concentrating-hormone (MCH) and orexin/hypocretin (OH) neurons mediate energy accumulation…”
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A deep learning algorithm for 3D cell detection in whole mouse brain image datasets by Tyson, Adam L, Rousseau, Charly V, Niedworok, Christian J, Keshavarzi, Sepiedeh, Tsitoura, Chryssanthi, Cossell, Lee, Strom, Molly, Margrie, Troy W

“…Understanding the function of the nervous system necessitates mapping the spatial distributions of its constituent cells defined by function, anatomy or gene…”
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The Stimulus Selectivity and Connectivity of Layer Six Principal Cells Reveals Cortical Microcircuits Underlying Visual Processing by Vélez-Fort, Mateo, Rousseau, Charly V., Niedworok, Christian J., Wickersham, Ian R., Rancz, Ede A., Brown, Alexander P.Y., Strom, Molly, Margrie, Troy W.

“…Sensory computations performed in the neocortex involve layer six (L6) cortico-cortical (CC) and cortico-thalamic (CT) signaling pathways. Developing an…”
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Donor template delivery by recombinant adeno-associated virus for the production of knock-in mice by Duddy, Graham, Courtis, Katherine, Horwood, Juliette, Olsen, Jessica, Horsler, Helen, Hodgson, Tina, Varsani-Brown, Sunita, Abdullah, Abdullah, Denti, Laura, Lane, Hollie, Delaqua, Fabio, Janzen, Julia, Strom, Molly, Rosewell, Ian, Crawley, Katharine, Davies, Benjamin

“…The ability of recombinant adeno-associated virus to transduce preimplantation mouse embryos has led to the use of this delivery method for the production of…”
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Analysis of segmentation ontology reveals the similarities and differences in connectivity onto L2/3 neurons in mouse V1 by Brown, Alexander P. Y., Cossell, Lee, Strom, Molly, Tyson, Adam L., Vélez-Fort, Mateo, Margrie, Troy W.

“…Quantitatively comparing brain-wide connectivity of different types of neuron is of vital importance in understanding the function of the mammalian cortex…”
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Phosphorylation of S776 and 14-3-3 binding modulate ataxin-1 interaction with splicing factors by de Chiara, Cesira, Menon, Rajesh P, Strom, Molly, Gibson, Toby J, Pastore, Annalisa

“…Ataxin-1 (Atx1), a member of the polyglutamine (polyQ) expanded protein family, is responsible for spinocerebellar ataxia type 1. Requirements for developing…”
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Multiple regions contribute to membrane targeting of Rab GTPases by Ali, Bassam R, Wasmeier, Christina, Lamoreux, Lynn, Strom, Molly, Seabra, Miguel C

“…Small GTPases of the Rab family are key regulators of membrane trafficking. Each Rab shows a characteristic subcellular distribution, and may serve as an…”
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Single Nucleotide Polymorphisms That Cause Structural Changes in the Cyclic AMP Receptor Protein Transcriptional Regulator of the Tuberculosis Vaccine Strain Mycobacterium bovis BCG Alter Global Gene Expression without Attenuating Growth by Hunt, Debbie M, Saldanha, José W, Brennan, John F, Benjamin, Pearline, Strom, Molly, Cole, Jeffrey A, Spreadbury, Claire L, Buxton, Roger S

“…Single nucleotide polymorphisms (SNPs) are present in the global transcriptional regulator cyclic AMP (cAMP) receptor protein (CRP) of the attenuated vaccine…”
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Isolated GH Deficiency Type II: Knockdown of the Harmful Δ3GH Recovers wt-GH Secretion in Rat Tumor Pituitary Cells by Lochmatter, Didier, Strom, Molly, Eblé, André, Petkovic, Vibor, Flück, Christa E, Bidlingmaier, Martin, Robinson, Iain C, Mullis, Primus E

“…Isolated GH deficiency type II (IGHD II) is the autosomal dominant form of GHD. In the majority of the cases, this disorder is due to specific GH-1 gene…”
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ABC Transporter Containing a Forkhead-Associated Domain Interacts with a Serine-Threonine Protein Kinase and Is Required for Growth of Mycobacterium tuberculosis in Mice by Curry, Juliet M, Whalan, Rachael, Hunt, Debbie M, Gohil, Kalpesh, Strom, Molly, Rickman, Lisa, Colston, M. Joseph, Smerdon, Stephen J, Buxton, Roger S

“…Forkhead-associated (FHA) domains are modular phosphopeptide recognition motifs with a striking preference for phosphothreonine-containing epitopes. FHA…”
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Visceral Obesity without Insulin Resistance in Late-Onset Obesity Rats by Bains, Randip K, Wells, Sara E, Flavell, Dave M, Fairhall, Keith M, Strom, Molly, Le Tissier, Paul, Robinson, Iain C. A. F

“…We describe a line of transgenic rats in which the males develop a unique autosomal dominant, late-onset obesity (LOB) phenotype. LOB males gradually…”
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A Circuit for Integration of Head- and Visual-Motion Signals in Layer 6 of Mouse Primary Visual Cortex by Vélez-Fort, Mateo, Bracey, Edward F., Keshavarzi, Sepiedeh, Rousseau, Charly V., Cossell, Lee, Lenzi, Stephen C., Strom, Molly, Margrie, Troy W.

“…To interpret visual-motion events, the underlying computation must involve internal reference to the motion status of the observer’s head. We show here that…”
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Inhibitory Interplay between Orexin Neurons and Eating by González, J. Antonio, Jensen, Lise T., Iordanidou, Panagiota, Strom, Molly, Fugger, Lars, Burdakov, Denis

“…In humans and rodents, loss of brain orexin/hypocretin (OH) neurons causes pathological sleepiness [1–4], whereas OH hyperactivity is associated with stress…”
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A Family of Rab27-binding Proteins by Strom, Molly, Hume, Alistair N., Tarafder, Abul K., Barkagianni, Eleni, Seabra, Miguel C.

“…The Rab27a GTPase regulates diverse processes involving lysosome-related organelles, including melanosome motility in melanocytes, and lytic granule release in…”
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The Importance of Two Conserved Arginine Residues for Catalysis by the Ras GTPase-activating Protein, Neurofibromin by Sermon, B A, Lowe, P N, Strom, M, Eccleston, J F

“…Ras proteins are guanine-nucleotide binding proteins that have a low intrinsic GTPase activity that is enhanced 10 5 -fold by the GTPase-activating proteins…”
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Cloning and Characterization of a rhoGAP Homolog fromDictyostelium discoideum by Ludbrook, Steven B., Eccleston, John F., Strom, Molly

“…Small GTPases interact with a variety of proteins that affect nucleotide binding and cleavage. GTPase activating proteins (GAPs) are one class of these…”
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A family of Rab27-binding proteins. Melanophilin links Rab27a and myosin Va function in melanosome transport by Strom, Molly, Hume, Alistair N, Tarafder, Abul K, Barkagianni, Eleni, Seabra, Miguel C

“…The Rab27a GTPase regulates diverse processes involving lysosome-related organelles, including melanosome motility in melanocytes, and lytic granule release in…”
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The Stimulus Selectivity and Connectivity of Layer Six Principal Cells Reveals Cortical Microcircuits Underlying Visual Processing by Vélez-Fort, Mateo, Rousseau, Charly V, Niedworok, Christian J, Wickersham, Ian R, Rancz, Ede A, Brown, Alexander P Y, Strom, Molly, Margrie, Troy W

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Isolated GH Deficiency Type II: Knockdown of the Harmful Delta 3GH Recovers wt-GH Secretion in Rat Tumor Pituitary Cells by Lochmatter, Didier, Strom, Molly, Eble, Andre, Petkovic, Vibor, Flueck, Christa E, Bidlingmaier, Martin, Robinson, Iain C, Mullis, Primus E

“…Isolated GH deficiency type II (IGHD II) is the autosomal dominant form of GHD. In the majority of the cases, this disorder is due to specific GH-1 gene…”
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The leaden Gene Product Is Required with Rab27a to Recruit Myosin Va to Melanosomes in Melanocytes by Hume, Alistair N., Collinson, Lucy M., Hopkins, Colin R., Strom, Molly, Barral, Duarte C., Bossi, Giovanna, Griffiths, Gillian M., Seabra, Miguel C.

“…The function of lysosome‐related organelles such as melanosomes in melanocytes, and lytic granules in cytotoxic T lymphocytes is disrupted in Griscelli…”
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