Search Results - "Strom, CE"

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    MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG by Rudd, Sean G, Gad, Helge, Sanjiv, Kumar, Amaral, Nuno, Hagenkort, Anna, Groth, Petra, Ström, Cecilia E, Mortusewicz, Oliver, Berglund, Ulrika Warpman, Helleday, Thomas

    Published in Cancer research (Chicago, Ill.) (01-09-2020)
    “…Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (e.g., 8-oxodGTP), which may kill cells if incorporated into DNA. Whether cancers avoid…”
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    Journal Article
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    Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy by Ström, Cecilia E, Helleday, Thomas

    Published in Biomolecules (Basel, Switzerland) (14-12-2012)
    “…Treatments with Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors have offered patients carrying cancers with mutated BRCA1 or BRCA2 genes a new…”
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