Search Results - "Strom, CE"
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MTH1 Inhibitor TH588 Disturbs Mitotic Progression and Induces Mitosis-Dependent Accumulation of Genomic 8-oxodG
Published in Cancer research (Chicago, Ill.) (01-09-2020)“…Reactive oxygen species (ROS) oxidize nucleotide triphosphate pools (e.g., 8-oxodGTP), which may kill cells if incorporated into DNA. Whether cancers avoid…”
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MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool (vol 508, pg 215, 2014)
Published in NATURE (27-04-2017)Get full text
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Corrigendum: MTH1 inhibition eradicates cancer by preventing sanitation of the dNTP pool
Published in Nature (London) (26-04-2017)Get full text
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Strategies for the Use of Poly(adenosine diphosphate ribose) Polymerase (PARP) Inhibitors in Cancer Therapy
Published in Biomolecules (Basel, Switzerland) (14-12-2012)“…Treatments with Poly(adenosine diphosphate ribose) polymerase (PARP) inhibitors have offered patients carrying cancers with mutated BRCA1 or BRCA2 genes a new…”
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