Search Results - "Strokes, Natalie"
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G protein-coupled receptor 56 and collagen III, a receptor-ligand pair, regulates cortical development and lamination
Published in Proceedings of the National Academy of Sciences - PNAS (02-08-2011)“…GPR56, an orphan G protein-coupled receptor (GPCR) from the family of adhesion GPCRs, plays an indispensable role in cortical development and lamination…”
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Disease-associated mutations prevent GPR56-collagen III interaction
Published in PloS one (04-01-2012)“…GPR56 is a member of the adhesion G protein-coupled receptor (GPCR) family. Mutations in GPR56 cause a devastating human brain malformation called bilateral…”
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Protective hinge in insulin opens to enable its receptor engagement
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-2014)“…Insulin provides a classical model of a globular protein, yet how the hormone changes conformation to engage its receptor has long been enigmatic. Interest has…”
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Loss of Col3a1, the gene for Ehlers-Danlos syndrome type IV, results in neocortical dyslamination
Published in PloS one (03-01-2012)“…It has recently been discovered that Collagen III, the encoded protein of the type IV Ehlers-Danlos Syndrome (EDS) gene, is one of the major constituents of…”
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Outcomes of Invasive and Noninvasive Ventilation in a Haitian Emergency Department
Published in Annals of global health (01-01-2023)“…Background: Limited data exist on the outcomes of patients requiring invasive ventilation or noninvasive positive pressure ventilation (NIPPV) in low-income…”
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Characterization of G protein-coupled receptor 56 protein expression in the mouse developing neocortex
Published in Journal of comparative neurology (1911) (01-09-2012)“…GPR56, one of the adhesion G‐protein–coupled receptors (GPCRs), plays an important role in the development of the cerebral cortex. Mutations in GPR56 cause a…”
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Adhesion-GPCRs in the CNS
Published in Advances in experimental medicine and biology (01-01-2010)“…There are a total of 33 members of adhesion G protein-coupled receptors (GPCRs) in humans and 30 members in mice and rats. More than half of these receptors…”
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8
Protective hinge in insulin opens to enable its receptor engagement
Published in Proceedings of the National Academy of Sciences - PNAS (19-08-2014)Get full text
Journal Article