Search Results - "Strohmeier, A."

Application of Designed Enzymes in Organic Synthesis by Strohmeier, Gernot A, Pichler, Harald, May, Oliver, Gruber-Khadjawi, Mandana

“…Strohmeier et al discuss an application of designed enzymes with regard to organic synthesis. Enzyme engineering is also examined…”
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Singlet oxygen generation as a major cause for parasitic reactions during cycling of aprotic lithium–oxygen batteries by Mahne, Nika, Schafzahl, Bettina, Leypold, Christian, Leypold, Mario, Grumm, Sandra, Leitgeb, Anita, Strohmeier, Gernot A., Wilkening, Martin, Fontaine, Olivier, Kramer, Denis, Slugovc, Christian, Borisov, Sergey M., Freunberger, Stefan A.

“…Non-aqueous metal–oxygen batteries depend critically on the reversible formation/decomposition of metal oxides on cycling. Irreversible parasitic reactions…”
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Biocatalytic reduction of carboxylic acids by Napora-Wijata, Kamila, Strohmeier, Gernot A., Winkler, Margit

“…An increasing demand for non‐petroleum‐based products is envisaged in the near future. Carboxylic acids such as citric acid, succinic acid, fatty acids, and…”
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Evolving the Promiscuity of Elizabethkingia meningoseptica Oleate Hydratase for the Regio‐ and Stereoselective Hydration of Oleic Acid Derivatives by Engleder, Matthias, Strohmeier, Gernot A., Weber, Hansjörg, Steinkellner, Georg, Leitner, Erich, Müller, Monika, Mink, Daniel, Schürmann, Martin, Gruber, Karl, Pichler, Harald

“…The addition of water to non‐activated carbon–carbon double bonds catalyzed by fatty acid hydratases (FAHYs) allows for highly regio‐ and stereoselective…”
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Structure-Based Mechanism of Oleate Hydratase from Elizabethkingia meningoseptica by Engleder, Matthias, Pavkov-Keller, Tea, Emmerstorfer, Anita, Hromic, Altijana, Schrempf, Sabine, Steinkellner, Georg, Wriessnegger, Tamara, Leitner, Erich, Strohmeier, Gernot A., Kaluzna, Iwona, Mink, Daniel, Schürmann, Martin, Wallner, Silvia, Macheroux, Peter, Gruber, Karl, Pichler, Harald

“…Hydratases provide access to secondary and tertiary alcohols by regio‐ and/or stereospecifically adding water to carbon‐carbon double bonds. Thereby, hydroxy…”
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Whole-cell (+)-ambrein production in the yeast Pichia pastoris by Moser, Sandra, Strohmeier, Gernot A., Leitner, Erich, Plocek, Thomas J., Vanhessche, Koenraad, Pichler, Harald

“…The triterpenoid (+)-ambrein is a natural precursor for (-)-ambrox, which constitutes one of the most sought-after fragrances and fixatives for the perfume…”
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Racemization-Free Chemoenzymatic Peptide Synthesis Enabled by the Ruthenium-Catalyzed Synthesis of Peptide Enol Esters via Alkyne-Addition and Subsequent Conversion Using Alcalase-Cross-Linked Enzyme Aggregates by Schröder, Hilmar, Strohmeier, Gernot A., Leypold, Mario, Nuijens, Timo, Quaedflieg, Peter J. L. M., Breinbauer, Rolf

“…The C‐terminal activation of peptides as prerequisite for the formation or ligation of peptide fragments is often associated with the problem of epimerization…”
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Engineering Pichia pastoris for improved NADH regeneration: A novel chassis strain for whole-cell catalysis by Geier, Martina, Brandner, Christoph, Strohmeier, Gernot A, Hall, Mélanie, Hartner, Franz S, Glieder, Anton

“…Many synthetically useful reactions are catalyzed by cofactor-dependent enzymes. As cofactors represent a major cost factor, methods for efficient cofactor…”
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Enzymatic One‐Step Reduction of Carboxylates to Aldehydes with Cell‐Free Regeneration of ATP and NADPH by Strohmeier, Gernot A., Eiteljörg, Inge C., Schwarz, Anna, Winkler, Margit

“…The direct generation of aldehydes from carboxylic acids is often a challenging synthetic task but undoubtedly attractive in view of abundant supply of such…”
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Expanding the threonine aldolase toolbox for the asymmetric synthesis of tertiary α-amino acids by Fesko, Kateryna, Strohmeier, Gernot A, Breinbauer, Rolf

“…The direct biochemical synthesis of tertiary α-amino acids with a wide range of diversity was recently reported using natural threonine aldolases LTA from…”
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Co-factor demand and regeneration in the enzymatic one-step reduction of carboxylates to aldehydes in cell-free systems by Strohmeier, Gernot A., Schwarz, Anna, Andexer, Jennifer N., Winkler, Margit

“…•Polyphosphate (polyP) sources differ significantly in their capability to provide reactive phosphate groups for the polyphosphate kinase-based ATP…”
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Nanoscale Structure and Dynamics of Model Membrane Lipid Raft Systems, Studied by Neutron Scattering Methods by Ahmadi, Delaram, Thompson, Katherine C., García Sakai, Victoria, Schweins, Ralf, Moulin, Martine, Haertlein, Michael, Strohmeier, Gernot A., Pichler, Harald, Forsyth, V. Trevor, Barlow, David J., Lawrence, M. Jayne, Foglia, Fabrizia

“…Quasi-elastic neutron scattering (QENS) and small angle neutron scattering (SANS), in combination with isotopic contrast variation, have been used to determine…”
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Application of Threonine Aldolases for the Asymmetric Synthesis of α‐Quaternary α‐Amino Acids by Blesl, Julia, Trobe, Melanie, Anderl, Felix, Breinbauer, Rolf, Strohmeier, Gernot A., Fesko, Kateryna

“…We report the synthesis of diverse β‐hydroxy‐α,α‐dialkyl‐α‐amino acids with perfect stereoselectivity for the α‐quaternary center through the action of l‐ and…”
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The impact of deuteration on natural and synthetic lipids: A neutron diffraction study by Luchini, Alessandra, Delhom, Robin, Demé, Bruno, Laux, Valérie, Moulin, Martine, Haertlein, Michael, Pichler, Harald, Strohmeier, Gernot A., Wacklin, Hanna, Fragneto, Giovanna

“…[Display omitted] •Neutron diffraction used to investigate natural and synthetic lipid mixtures.•Extracts composition changes for cells grown in deuterated or…”
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Discovery and structural characterisation of new fold type IV-transaminases exemplify the diversity of this enzyme fold by Pavkov-Keller, Tea, Strohmeier, Gernot A., Diepold, Matthias, Peeters, Wilco, Smeets, Natascha, Schürmann, Martin, Gruber, Karl, Schwab, Helmut, Steiner, Kerstin

“…Transaminases are useful biocatalysts for the production of amino acids and chiral amines as intermediates for a broad range of drugs and fine chemicals. Here,…”
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Enantiocomplementary Yarrowia lipolytica Oxidoreductases: Alcohol Dehydrogenase 2 and Short Chain Dehydrogenase/Reductase by Napora-Wijata, Kamila, Strohmeier, Gernot A, Sonavane, Manoj N, Avi, Manuela, Robins, Karen, Winkler, Margit

“…Enzymes of the non-conventional yeast Yarrowia lipolytica seem to be tailor-made for the conversion of lipophilic substrates. Herein, we cloned and…”
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Combinatorial Synthesis of Functionalized 1,3-Thiazine Libraries Using a Combined Polymer-Supported Reagent/Catch-and-Release Strategy by Strohmeier, Gernot A., Kappe, C. Oliver

“…A dual role: The supported sulfonic acid reagent promotes the ring closure of the thiazine products and also binds them in situ as ion pairs (see scheme). The…”
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Localization of Cholesterol within Supported Lipid Bilayers Made of a Natural Extract of Tailor-Deuterated Phosphatidylcholine by Waldie, Sarah, Lind, Tania K, Browning, Kathryn, Moulin, Martine, Haertlein, Michael, Forsyth, V. Trevor, Luchini, Alessandra, Strohmeier, Gernot A, Pichler, Harald, Maric, Selma, Cárdenas, Marité

“…Cholesterol is an essential component of mammalian membranes and is known to induce a series of physicochemical changes in the lipid bilayer. Such changes…”
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Investigation of one-enzyme systems in the ω-transaminase-catalyzed synthesis of chiral amines by Fesko, Kateryna, Steiner, Kerstin, Breinbauer, Rolf, Schwab, Helmut, Schürmann, Martin, Strohmeier, Gernot A.

“…•(S)- and (R)-aromatic amines were synthesized using ω-transaminases.•Good to excellent conversions and e.e.-values of the amine products were…”
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The Production of Matchout-Deuterated Cholesterol and the Study of Bilayer-Cholesterol Interactions by Waldie, Sarah, Moulin, Martine, Porcar, Lionel, Pichler, Harald, Strohmeier, Gernot A., Skoda, Maximilian, Forsyth, V. Trevor, Haertlein, Michael, Maric, Selma, Cárdenas, Marité

“…The deuteration of biomolecules provides advanced opportunities for neutron scattering studies. For low resolution studies using techniques such as small-angle…”
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