Search Results - "Strochlic, Todd I."

Ack kinase regulates CTP synthase filaments during Drosophila oogenesis by Strochlic, Todd I, Stavrides, Kevin P, Thomas, Sam V, Nicolas, Emmanuelle, O'Reilly, Alana M, Peterson, Jeffrey R

“…The enzyme CTP synthase (CTPS) dynamically assembles into macromolecular filaments in bacteria, yeast, Drosophila , and mammalian cells, but the role of this…”
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The protein kinase CK2 substrate Jabba modulates lipid metabolism during Drosophila oogenesis by McMillan, Emily A., Longo, Sheila M., Smith, Michael D., Broskin, Sarah, Lin, Baicheng, Singh, Nisha K., Strochlic, Todd I.

“…Lipid metabolism plays a critical role in female reproduction. During oogenesis, maturing oocytes accumulate high levels of neutral lipids that are essential…”
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Grd19/Snx3p functions as a cargo-specific adapter for retromer-dependent endocytic recycling by Strochlic, Todd I, Setty, Thanuja Gangi, Sitaram, Anand, Burd, Christopher G

“…Amajor function of the endocytic system is the sorting of cargo to various organelles. Endocytic sorting of the yeast reductive iron transporter, which is…”
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Copper Modulates the Catalytic Activity of Protein Kinase CK2 by Chojnowski, John E, Li, Rongrong, Tsang, Tiffany, Alfaran, Fatimah H, Dick, Alexej, Cocklin, Simon, Brady, Donita C, Strochlic, Todd I

“…Casein kinase 2 (CK2) is an evolutionarily conserved serine/threonine kinase implicated in a wide range of cellular functions and known to be dysregulated in…”
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Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking by Strochlic, Todd I, Concilio, Susanna, Viaud, Julien, Eberwine, Ryan A, Wong, Lisa Epstein, Minden, Audrey, Turk, Benjamin E, Plomann, Markus, Peterson, Jeffrey R

“…Synaptic transmission is mediated by a complex set of molecular events that must be coordinated in time and space. While many proteins that function at the…”
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MAPKAP kinase 2–mediated phosphorylation of HspA1L protects male germ cells from heat stress–induced apoptosis by Williams, Patrick A., Kobilnyk, Heather E., McMillan, Emily A., Strochlic, Todd I.

“…Developing male germ cells are extremely sensitive to heat stress; consequently, anatomic and physiologic adaptations have evolved to maintain proper…”
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Diet controls Drosophila follicle stem cell proliferation via Hedgehog sequestration and release by Hartman, Tiffiney R, Strochlic, Todd I, Ji, Yingbiao, Zinshteyn, Daniel, O'Reilly, Alana M

“…A healthy diet improves adult stem cell function and delays diseases such as cancer, heart disease, and neurodegeneration. Defining molecular mechanisms by…”
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Phosphorylation of the RNA-binding protein Dazl by MAPKAP kinase 2 regulates spermatogenesis by Williams, Patrick A, Krug, Michael S, McMillan, Emily A, Peake, Jasmine D, Davis, Tara L, Cocklin, Simon, Strochlic, Todd I

“…Developing male germ cells are exquisitely sensitive to environmental insults such as heat and oxidative stress. An additional characteristic of these cells is…”
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Identification of Novel CK2 Kinase Substrates Using a Versatile Biochemical Approach by Chojnowski, John E, McMillan, Emily A, Strochlic, Todd I

“…The study of kinase-substrate relationships is essential to gain a complete understanding of the functions of these enzymes and their downstream targets in…”
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Opposing activities of the Snx3-retromer complex and ESCRT proteins mediate regulated cargo sorting at a common endosome by Strochlic, Todd I, Schmiedekamp, Briana C, Lee, Jacqueline, Katzmann, David J, Burd, Christopher G

“…Endocytosed proteins are either delivered to the lysosome to be degraded or are exported from the endosomal system and delivered to other organelles. Sorting…”
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Golgi targeting of ARF-like GTPase Arl3p requires its N[alpha]-acetylation and the integral membrane protein Sys1p by Subba Rao Gangi Setty, Strochlic, Todd I, Yan Tong, Amy Hin, Boone, Charles, Burd, Christopher G

“…Myristoylation of ARF family GTPases is required for their association with Golgi and endosomal membranes, where they regulate protein sorting and the lipid…”
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Phosphoinositides Are Essential Coactivators for p21-Activated Kinase 1 by Strochlic, Todd I., Viaud, Julien, Rennefahrt, Ulrike E.E., Anastassiadis, Theonie, Peterson, Jeffrey R.

“…Phospholipid-enriched membranes such as the plasma membrane can serve as direct regulators of kinase signaling. Pak1 is involved in growth factor signaling at…”
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Golgi targeting of ARF-like GTPase Arl3p requires its N α -acetylation and the integral membrane protein Sys1p by Burd, Christopher G, Setty, Subba Rao Gangi, Strochlic, Todd I, Tong, Amy Hin Yan, Boone, Charles

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Arf-like GTPases: not so Arf-like after all by Burd, Christopher G., Strochlic, Todd I., Setty, Subba R. Gangi

“…ADP-ribosylation factor (Arf) GTP-binding proteins are among the best-characterized members of the Ras superfamily of GTPases, with well-established functions…”
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Phosphoinositides are essential co-activators for p21-activated kinase 1 (Pak1) by Strochlic, Todd I., Viaud, Julien, Rennefahrt, Ulrike E. E., Anastassiadis, Theonie, Peterson, Jeffrey R.

“…Phospholipid-enriched membranes such as the plasma membrane can serve as direct regulators of kinase signaling. Pak1 is involved in growth factor signaling at…”
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Gaining Wings to FLY: Using Drosophila Oogenesis as an Entry Point for Citizen Scientists in Laboratory Research by Ruiz-Whalen, Dara M, Aichele, Christopher P, Dyson, Ebony R, Gallen, Katherine C, Stark, Jennifer V, Saunders, Jasmine A, Simonet, Jacqueline C, Ventresca, Erin M, Fuentes, Isabela M, Marmol, Nyellis, Moise, Emly, Neubert, Benjamin C, Riggs, Devon J, Self, Ava M, Alexander, Jennifer I, Boamah, Ernest, Browne, Amanda J, Correa, Iliana, Foster, Maya J, Harrington, Nicole, Holiday, Troy J, Henry, Ryan A, Lee, Eric H, Longo, Sheila M, Lorenz, Laurel D, Martinez, Esteban, Nikonova, Anna, Radu, Maria, Smith, Shannon C, Steele, Lindsay A, Strochlic, Todd I, Archer, Nicholas F, Aykit, Y James, Bolotsky, Adam J, Boyle, Megan, Criollo, Jennifer, Eldor, Oren, Cruz, Gabriela, Fortuona, Valerie N, Gounder, Shreeya D, Greenwood, Nyim, Ji, Kayla W, Johnson, Aminah, Lara, Sophie, Montanez, Brianna, Saurman, Maxwell, Singh, Tanu, Smith, Daniel R, Stapf, Catherine A, Tondapu, Tarang, Tsiobikas, Christina, Habas, Raymond, O'Reilly, Alana M

“…Citizen science is a productive approach to include non-scientists in research efforts that impact particular issues or communities. In most cases, scientists…”
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Golgi targeting of ARF-like GTPase Arl3p requires its Nalpha-acetylation and the integral membrane protein Sys1p by Setty, Subba Rao Gangi, Strochlic, Todd I, Tong, Amy Hin Yan, Boone, Charles, Burd, Christopher G

“…Myristoylation of ARF family GTPases is required for their association with Golgi and endosomal membranes, where they regulate protein sorting and the lipid…”
Get full text