Search Results - "Strocchi, Paola"

Detection of ricin and other ribosome-inactivating proteins by an immuno-polymerase chain reaction assay by Lubelli, Chiara, Chatgilialoglu, Alexandros, Bolognesi, Andrea, Strocchi, Paola, Colombatti, Marco, Stirpe, Fiorenzo

“…Ribosome-inactivating proteins (RIPs) are plant proteins with enzymatic activity, classified as type 1 (single chain) or type 2 (two chains). They are…”
Get full text

Up-regulation of cDK5/p35 by oxidative stress in human neuroblastoma IMR-32 cells by Strocchi, Paola, Pession, Annalisa, Dozza, Barbara

“…Cdk5, a member of the cyclin‐dependent kinase (cdk) family, is predominately active in neurons, where its activity is tightly regulated by the binding of its…”
Get full text

Changes in the activity of cdk2 and cdk5 accompany differentiation of rat primary oligodendrocytes by Tang, Xue-Ming, Strocchi, Paola, Cambi, Franca

“…Oligodendrocytes, the myelinating cells of the central nervous system, are terminally differentiated cells that originate through asynchronous waves of…”
Get full text

Generation of Reactive Oxygen Species by Mitochondrial Complex I: Implications in Neurodegeneration by Fato, Romana, Bergamini, Christian, Leoni, Serena, Strocchi, Paola, Lenaz, Giorgio

“…Mitochondrial Complex I [NADH Coenzyme Q (CoQ) oxidoreductase] is the least understood of respiratory complexes. In this review we emphasize some novel…”
Get full text

Neuronal loss up-regulates clusterin mRNA in living neurons and glial cells in the rat brain by Strocchi, Paola, Rauzi, Francesca, Cevolani, Daniela

Get full text

Clusterin up-regulation following sub-lethal oxidative stress and lipid peroxidation in human neuroblastoma cells by Strocchi, Paola, Smith, Mark A., Perry, George, Tamagno, Elena, Danni, Oliviero, Pession, Annalisa, Gaiba, Alessia, Dozza, Barbara

“…Clusterin/apolipoprotein J is a multifunctional protein up-regulated during various pathophysiological states. Since oxidative stress plays an important role…”
Get full text

Oxidative Stress Induces Increase in Intracellular Amyloid β-Protein Production and Selective Activation of βI and βII PKCs in NT2 Cells by Paola, Dimitri, Domenicotti, Cinzia, Nitti, Mariapaola, Vitali, Antonella, Borghi, Roberta, Cottalasso, Damiano, Zaccheo, Damiano, Odetti, Patrizio, Strocchi, Paola, Marinari, Umberto M., Tabaton, Massimo, Pronzato, Maria A.

“…Amyloid β-protein (Aβ) aggregation produces an oxidative stress in neuronal cells that, in turn, may induce an amyloidogenic shift of neuronal metabolism. To…”
Get full text

Characterization of highly toxic type 2 ribosome-inactivating proteins from Adenia lanceolata and Adenia stenodactyla (Passifloraceae) by Stirpe, Fiorenzo, Bolognesi, Andrea, Bortolotti, Massimo, Farini, Valentina, Lubelli, Chiara, Pelosi, Emanuele, Polito, Letizia, Dozza, Barbara, Strocchi, Paola, Chambery, Angela, Parente, Augusto, Barbieri, Luigi

“…From the caudices of the Passifloraceae Adenia lanceolata and A. stenodactyla, two lectins called lanceolin and stenodactylin, respectively, were purified by…”
Get full text

Regulation of glycogen synthase kinase‐3β by products of lipid peroxidation in human neuroblastoma cells by Dozza, Barbara, Smith, Mark A., Perry, George, Tabaton, Massimo, Strocchi, Paola

“…The potential role of 4‐hydroxynonenal (HNE), a major product of membrane lipid peroxidation, in regulating glycogen synthase kinase‐3β (GSK3β) activity was…”
Get full text

The characterization of tubulin in CNS membrane fractions by Strocchi, P, Brown, B A, Young, J D, Bonventre, J A, Gilbert, J M

“…Rough endoplasmic reticulum (RER), smooth endoplasmic reticulum (SER), and a plasma membrane (PM) fraction enriched in synaptic membranes were isolated from…”
Get more information

Studies on the biosynthesis of intermediate filament proteins in the rat CNS by Strocchi, P, Dahl, D, Gilbert, J M

“…The biosynthesis of brain intermediate filament proteins [neurofilament proteins and glial fibrillary acidic protein (GFA)] was studied with cell-free systems…”
Get more information

Microanatomical changes of intracerebral arteries in spontaneously hypertensive rats: a model of cerebrovascular disease of the elderly by Sabbatini, Maurizio, Strocchi, Paola, Vitaioli, Lucia, Amenta, Francesco

“…Changes occurring in intracerebral arteries of 24-week-old spontaneously hypertensive rats (SHR) compared with age-matched normotensive Wistar–Kyoto (WKY) rats…”
Get full text

Lesions Caused by Ricin Applied to Rabbit Eyes by Strocchi, Paola, Dozza, Barbara, Pecorella, Irene, Fresina, Michela, Campos, Emilio, Stirpe, Fiorenzo

“…Ricin, a highly potent toxin from castor beans, is a potential biological weapon that could be dispersed in the air as dust or aerosol. In these forms, ricin,…”
Get full text

Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells by Dozza, Barbara, Smith, Mark A, Perry, George, Tabaton, Massimo, Strocchi, Paola

“…The potential role of 4-hydroxynonenal (HNE), a major product of membrane lipid peroxidation, in regulating glycogen synthase kinase-3beta (GSK3beta) activity…”
Get full text

P1-286 Glycogen synthase kinase-3β activity is regulated by products of lipid peroxidation: relevance to Alzheimer disease by Strocchi, Paola, Smith, Mark A., Perry, George, Tabaton, Massimo, Dozza, Barbara

Get full text

Protein levels of glycogen synthase 3 kinase are normal in progressive supranuclear palsy by Borghi, Roberta, Piccini, Alessandra, Delacourte, Andrè, Strocchi, Paola, Zaccheo, Damiano, Tabaton, Massimo

“…Progressive supranuclear palsy (PSP) is a neurodegenerative disorder characterized by pure neurofibrillary tau pathology involving mainly basal ganglia and…”
Get full text

Changes of retinal neurons and glial fibrillary acid protein immunoreactive astrocytes in spontaneously hypertensive rats by Sabbatini, Maurizio, Strocchi, Paola, Vitaioli, Lucia, Amenta, Francesco

“…OBJECTIVE The influence of arterial hypertension on retinal neurons and glial fibrillary acid protein (GFAP) immunoreactive astrocytes was investigated in…”
Get full text

Vascular and neuronal hypertensive brain damage: protective effect of treatment with nicardipine by Amenta, F, Strocchi, P, Sabbatini, M

“…The brain is sensitive to hypertension, which causes a variety of vascular and neuronal cerebral changes. The present study was designed to assess the effect…”
Get more information

Glial reaction to volkensin-induced selective degeneration of central neurons by Cevolani, Daniela, Bentivoglio, Marina, Strocchi, Paola

“…Volkensin, a highly toxic protein retrogradely transported through axons, was used to target primary neuronal death in brainstem precerebellar relays after…”
Get full text

Molecular diagnosis of transthyretin Met 30 mutation in an Italian family with familial amyloidotic polyneuropathy by Strocchi, Paola, Tang, Xue-Ming, Cambi, Franca

“…We report the molecular analysis of the transthyretin gene in a large Italian pedigree with familial amyloidotic polyneuropathy and demonstrate the presence of…”
Get full text