Search Results - "Ströhl, Florian"
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C-terminal calcium binding of α-synuclein modulates synaptic vesicle interaction
Published in Nature communications (19-02-2018)“…Alpha-synuclein is known to bind to small unilamellar vesicles (SUVs) via its N terminus, which forms an amphipathic alpha-helix upon membrane interaction…”
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2
Fluorescence Self-Quenching from Reporter Dyes Informs on the Structural Properties of Amyloid Clusters Formed in Vitro and in Cells
Published in Nano letters (11-01-2017)“…The characterization of the aggregation kinetics of protein amyloids and the structural properties of the ensuing aggregates are vital in the study of the…”
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3
RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
Published in Neuron (Cambridge, Mass.) (16-08-2017)“…Nascent proteins can be positioned rapidly at precise subcellular locations by local protein synthesis (LPS) to facilitate localized growth responses. Axon…”
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4
On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
Published in Cell reports (Cambridge) (10-12-2019)“…Ribosome assembly occurs mainly in the nucleolus, yet recent studies have revealed robust enrichment and translation of mRNAs encoding many ribosomal proteins…”
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5
A concept for single-shot volumetric fluorescence imaging via orthogonally polarized excitation lattices
Published in Scientific reports (23-04-2019)“…The deconvolution of widefield fluorescence images provides only guesses of spatial frequency information along the optical axis due to the so called missing…”
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6
Rapid prototyping of 1xN multifocus gratings via additive direct laser writing
Published in Micro and Nano Engineering (01-06-2023)“…Multifocus gratings (MFGs) enable microscopes and other imaging systems to record entire Z-stacks of images in a single camera exposure. The exact grating…”
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7
S-polarized light-sheets improve resolution and light-efficiency in oblique plane microscopy
Published in Scientific reports (12-02-2024)“…Oblique plane microscopy (OPM) offers 3D optically sectioned imaging with high spatial- and temporal-resolution while enabling conventional sample mounting…”
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8
Superresolving the kidney—a practical comparison of fluorescence nanoscopy of the glomerular filtration barrier
Published in Analytical and bioanalytical chemistry (01-02-2021)“…Immunofluorescence microscopy is routinely used in the diagnosis of and research on renal impairments. However, this highly specific technique is restricted in…”
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Single Molecule Translation Imaging Visualizes the Dynamics of Local β-Actin Synthesis in Retinal Axons
Published in Scientific reports (06-04-2017)“…Local mRNA translation occurs in growing axons enabling precise control of the proteome in response to signals. To measure quantitatively the spatiotemporal…”
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10
Three-dimensional structured illumination microscopy data of mitochondria and lysosomes in cardiomyoblasts under normal and galactose-adapted conditions
Published in Scientific data (23-03-2022)“…This three-dimensional structured illumination microscopy (3DSIM) dataset was generated to highlight the suitability of 3DSIM to investigate…”
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OptiJ: Open-source optical projection tomography of large organ samples
Published in Scientific reports (30-10-2019)“…The three-dimensional imaging of mesoscopic samples with Optical Projection Tomography (OPT) has become a powerful tool for biomedical phenotyping studies. OPT…”
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Label-free superior contrast with c-band ultra-violet extinction microscopy
Published in Light, science & applications (03-03-2023)“…In 1934, Frits Zernike demonstrated that it is possible to exploit the sample’s refractive index to obtain superior contrast images of biological cells. The…”
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Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy
Published in Nanophotonics (Berlin, Germany) (2022)“…The article elucidates the physical mechanism behind the generation of superior-contrast and high-resolution label-free images using an optical waveguide…”
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Erratum to: Multi-moded high-index contrast optical waveguide for super-contrast high-resolution label-free microscopy
Published in Nanophotonics (Berlin, Germany) (26-09-2022)Get full text
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15
Total internal reflection fluorescence anisotropy imaging microscopy: setup, calibration, and data processing for protein polymerization measurements in living cells
Published in Methods and applications in fluorescence (19-12-2017)“…Fluorescence anisotropy imaging microscopy (FAIM) measures the depolarization properties of fluorophores to deduce molecular changes in their environment. For…”
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16
FUS Phase Separation Is Modulated by a Molecular Chaperone and Methylation of Arginine Cation-π Interactions
Published in Cell (19-04-2018)“…Reversible phase separation underpins the role of FUS in ribonucleoprotein granules and other membrane-free organelles and is, in part, driven by the…”
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17
A Guide to Structured Illumination TIRF Microscopy at High Speed with Multiple Colors
Published in Journal of visualized experiments (30-05-2016)“…Optical super-resolution imaging with structured illumination microscopy (SIM) is a key technology for the visualization of processes at the molecular level in…”
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On‐Chip Super‐Resolution Imaging with Fluorescent Polymer Films
Published in Advanced functional materials (01-07-2019)“…Wide field‐of‐view (FOV), label‐free, super‐resolution imaging is demonstrated using a specially designed waveguide chip that can illuminate a sample with…”
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Frontiers in structured illumination microscopy
Published in Optica (20-06-2016)Get full text
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20
Object detection neural network improves Fourier ptychography reconstruction
Published in Optics express (07-12-2020)“…High resolution microscopy is heavily dependent on superb optical elements and superresolution microscopy even more so. Correcting unavoidable optical…”
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