Search Results - "Strissel, P. L."
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Regulation of the NRSF/REST gene by methylation and CREB affects the cellular phenotype of small-cell lung cancer
Published in Oncogene (28-10-2010)“…The neuron-restrictive silencer factor/RE1-silencing transcription factor (NRSF/REST) is a negative regulator of gene expression restricting the expression of…”
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2
Hypermethylation and loss of retinoic acid receptor responder 1 expression in human choriocarcinoma
Published in Journal of experimental & clinical cancer research (23-11-2017)“…Human placental development resembles tumorigenesis, due to the invasive and fusogenic potential of trophoblasts. However, these features are tightly…”
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3
Polymorphisms in the novel serotonin receptor subunit gene HTR3C show different risks for acute chemotherapy-induced vomiting after anthracycline chemotherapy
Published in Journal of cancer research and clinical oncology (01-10-2008)“…The aim of this study was to correlate chemotherapy-induced nausea and vomiting (CINV) with commonly occurring single nucleotide polymorphisms (SNP) in the…”
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4
Contribution of different placental cells to the expression and stimulation of antimicrobial proteins (AMPs)
Published in Placenta (Eastbourne) (01-11-2011)“…Abstract The placenta is a major barrier that prevents potentially infectious agents from causing fetal diseases or related complications during pregnancy…”
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5
Single nucleotide polymorphism D1853N of the ATM gene may alter the risk for breast cancer
Published in Journal of cancer research and clinical oncology (01-08-2008)“…Purpose Various ATM (ataxia telangiectasia-mutated) mutations and polymorphisms have been reported to be associated with an increased breast cancer risk…”
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6
DNA structural properties of AF9 are similar to MLL and could act as recombination hot spots resulting in MLL/AF9 translocations and leukemogenesis
Published in Human molecular genetics (01-07-2000)“…The human AF9 gene at 9p22 is one of the most common fusion partner genes with the MLL gene at 11q23, resulting in the t(9;11)(p22;q23). The MLL-AF9 fusion…”
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Evaluation of clinical parameters and estrogen receptor alpha gene polymorphisms for patients with endometriosis
Published in Reproduction (Cambridge, England) (01-01-2006)“…Endometriosis is a chronic inflammatory disease, which is especially found in women with subfertility problems with an incidence of up to 30%. The disease is…”
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DNA sequence variations of the entire anti-Müllerian hormone (AMH) gene promoter and AMH protein expression in patients with the Mayer–Rokitanski–Küster–Hauser syndrome
Published in Human reproduction (Oxford) (01-01-2005)“…BACKGROUND: The etiology of the Mayer–Rokitanski–Küster–Hauser (MRKH) syndrome, where congenitally the Müllerian ducts fail to develop into the uterus, cervix…”
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9
An In vivo topoisomerase II cleavage site and a DNase I hypersensitive site colocalize near exon 9 in the MLL breakpoint cluster region
Published in Blood (15-11-1998)“…The human myeloid-lymphoid leukemia gene, MLL (also called ALL-1, Htrx, or HRX ), maps to chromosomal band 11q23. MLL is involved in translocations that result…”
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10
Specific Mg2+ binding to AT-rich regions of chromatin in the evolution of eukaryotes
Published in Applied surface science (30-07-2006)“…At SIMS XIV, we reported SIMS evidence of specific Mg2+ binding to the AT-rich regions of human metaphase chromosomes represented by G-bands. Subsequent…”
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Cation-Chromatin Binding as Shown by Ion Microscopy Is Essential for the Structural Integrity of Chromosomes
Published in The Journal of cell biology (10-12-2001)“…Mammalian interphase and mitotic cells were analyzed for their cation composition using a three-dimensional high resolution scanning ion microprobe. This…”
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12
Higher incidence of linked malformations in siblings of Mayer–Rokitansky–Küster–Hauser-syndrome patients
Published in Human reproduction (Oxford) (01-05-2008)“…BACKGROUND Mayer–Rokitansky–Küster–Hauser (MRKH) syndrome is a malformation of the female genital tract (vaginal aplasia, rudimentary uterus, normal fallopian…”
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13
Dietary Bioflavonoids Induce Cleavage in the MLL Gene and May Contribute to Infant Leukemia
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2000)“…Chromosomal translocations involving the MLL gene occur in about 80% of infant leukemia. In the search for possible agents inducing infant leukemia, we…”
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Assessment of pituitary and steroid hormones and members of the TGF-beta superfamily for ovarian function in patients with congenital uterus and vaginal aplasia (MRKH syndrome)
Published in Hormone and metabolic research (01-05-2009)“…Patients with Mayer-Rokitanski-Kuster-Hauser (MRKH) syndrome have congenital uterine and vaginal aplasia. The main question of this study was, if the absence…”
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15
Risk Factors for Endometriosis in a German Case-Control Study
Published in Geburtshilfe und Frauenheilkunde (01-12-2011)“…The etiology of endometriosis is still a research field in which few consistent data are available. Large case-control studies or even cohort studies are rare,…”
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16
Scaffold-Associated Regions in the Human Type I Interferon Gene Cluster on the Short Arm of Chromosome 9
Published in Genomics (San Diego, Calif.) (15-01-1998)“…Scaffold-associated regions (SARs) function at the level of modeling or shaping the chromatin of DNA into loop domains. We have mapped 36 SARs in the human…”
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Polymorphisms in estrogen metabolism and estrogen pathway genes and the risk of miscarriage
Published in Archives of gynecology and obstetrics (01-09-2009)“…Purpose This study investigated genetic variations in the estrogen pathway and their association with miscarriages. Methods A total of 483 patients were…”
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AF10 Is Split by MLL and HEAB, a Human Homolog to a Putative Caenorhabditis elegans ATP/GTP-Binding Protein in an Invins(10; 11)(p12;q23q12)
Published in Blood (01-11-1996)“…Invins(10;11)(p12;q23q12) is one of the rare but recurring chromosome rearrangements seen in acute monoblastic leukemia. We cloned the proximal 10p breakpoint…”
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Common chromatin structures at breakpoint cluster regions may lead to chromosomal translocations found in chronic and acute leukemias
Published in Human genetics (01-06-2006)“…The t(9;22) BCR/ABL fusion is associated with over 90% of chronic myelogenous and 25% of acute lymphocytic leukemia. Chromosome 11q23 translocations in acute…”
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20
High resolution SIMS imaging of cations in mammalian cell mitosis, and in Drosophila polytene chromosomes
Published in Applied surface science (30-07-2006)“…The University of Chicago high resolution scanning ion microprobe (UC-SIM) was used to image, by Secondary Ion Mass Spectrometry (SIMS), the distribution of Ca…”
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Journal Article Conference Proceeding