Search Results - "Stringfield, Sierra J."
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Adolescent alcohol exposure persistently alters orbitofrontal cortical encoding of Pavlovian conditional stimulus components in female rats
Published in Scientific reports (14-06-2024)“…Exposure to alcohol during adolescence impacts cortical and limbic brain regions undergoing maturation. In rodent models, long-term effects on behavior and…”
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Changes in dorsomedial striatum activity during expression of goal-directed vs. habit-like cue-induced cocaine seeking
Published in Addiction neuroscience (01-06-2024)“…A preclinical model of cue exposure therapy, cue extinction, reduces cue-induced cocaine seeking that is goal-directed but not habit-like. Goal-directed and…”
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Sex differences in nicotine-enhanced Pavlovian conditioned approach in rats
Published in Biology of sex differences (17-07-2019)“…Nicotine exposure enhances Pavlovian conditioned approach (PCA), or the learned approach to reward-predictive cues. While females show elevated approach to…”
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Changes in sensitivity of reward and motor behavior to dopaminergic, glutamatergic, and cholinergic drugs in a mouse model of fragile X syndrome
Published in PloS one (18-10-2013)“…Fragile X syndrome (FXS) is a leading cause of intellectual disability. FXS is caused by loss of function of the FMR1 gene, and mice in which Fmr1 has been…”
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Intravenous self-administration of delta-9-THC in adolescent rats produces long-lasting alterations in behavior and receptor protein expression
Published in Psychopharmacology (01-01-2021)“…Rationale Initial exposure to cannabinoids, including Δ-9-tetrahydrocannabinol (THC), often occurs during adolescence. Considerable neurodevelopmental…”
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Disentangling the lasting effects of adolescent cannabinoid exposure
Published in Progress in neuro-psychopharmacology & biological psychiatry (10-01-2021)“…Cannabis is the most widely used illicit substance among adolescents, and adolescent cannabis use is associated with various neurocognitive deficits that can…”
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Working Memory Performance Predicts, but Does Not Reduce, Cocaine and Cannabinoid Seeking in Adult Male Rats
Published in The international journal of neuropsychopharmacology (01-10-2024)“…Abstract Background Cognitive deficits reflecting impaired executive function are commonly associated with psychiatric disorders, including substance use…”
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Nicotine Enhances Intravenous Self-administration of Cannabinoids in Adult Rats
Published in Nicotine & tobacco research (06-04-2023)“…Abstract Introduction Nicotine and cannabis are commonly used together, yet few studies have investigated the effects of concurrent administration. Nicotine…”
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Nicotine-enhanced Pavlovian conditioned approach is resistant to omission of expected outcome
Published in Behavioural brain research (02-05-2018)“…•Conditioned stimuli and responses are key components of nicotine use and relapse.•Conditioned responses can be modeled in animals with Pavlovian conditioned…”
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Sex and Adolescent Ethanol Exposure Influence Pavlovian Conditioned Approach
Published in Alcoholism, clinical and experimental research (01-04-2017)“…Background Alcohol use among adolescents is widespread and a growing concern due to long‐term behavioral deficits, including altered Pavlovian behavior, that…”
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Orbitofrontal participation in sign- and goal-tracking conditioned responses: Effects of nicotine
Published in Neuropharmacology (01-04-2017)“…Pavlovian conditioned stimuli can acquire incentive motivational properties, and this phenomenon can be measured in animals using Pavlovian conditioned…”
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Requisite Role of Basolateral Amygdala Glucocorticoid Receptor Stimulation in Drug Context-Induced Cocaine-Seeking Behavior
Published in The international journal of neuropsychopharmacology (01-12-2016)“…Exposure to cocaine-associated stimuli triggers a robust rise in circulating glucocorticoid levels. Glucocorticoid receptors are richly expressed in the…”
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Correction to: Acute phenylalanine/tyrosine depletion of phasic dopamine in the rat brain
Published in Psychopharmacology (01-09-2018)“…After publication of this paper, the authors determined an error in the calculation of the norepinephrine standard concentrations for the HPLC calibration…”
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Acute phenylalanine/tyrosine depletion of phasic dopamine in the rat brain
Published in Psychopharmacology (01-06-2016)“…Rationale Dopamine plays a critical role in striatal and cortical function, and depletion of the dopamine precursors phenylalanine and tyrosine is used in…”
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