Search Results - "Strine, Madison S."

Comprehensive in vivo secondary structure of the SARS-CoV-2 genome reveals novel regulatory motifs and mechanisms by Huston, Nicholas C., Wan, Han, Strine, Madison S., de Cesaris Araujo Tavares, Rafael, Wilen, Craig B., Pyle, Anna Marie

“…Severe-acute-respiratory-syndrome-related coronavirus 2 (SARS-CoV-2) is the positive-sense RNA virus that causes coronavirus disease 2019 (COVID-19). The…”
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Tuft cells are key mediators of interkingdom interactions at mucosal barrier surfaces by Strine, Madison S, Wilen, Craig B

“…Although tuft cells were discovered over 60 years ago, their functions have long been enigmatic, especially in human health. Nonetheless, tuft cells have…”
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Systematic detection of tertiary structural modules in large RNAs and RNP interfaces by Tb-seq by Patel, Shivali, Sexton, Alec N., Strine, Madison S., Wilen, Craig B., Simon, Matthew D., Pyle, Anna Marie

“…Compact RNA structural motifs control many aspects of gene expression, but we lack methods for finding these structures in the vast expanse of multi-kilobase…”
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Stability of SARS-CoV-2 RNA in Nonsupplemented Saliva by Ott, Isabel M, Strine, Madison S, Watkins, Anne E, Boot, Maikel, Kalinich, Chaney C, Harden, Christina A, Vogels, Chantal B F, Casanovas-Massana, Arnau, Moore, Adam J, Muenker, M Catherine, Nakahata, Maura, Tokuyama, Maria, Nelson, Allison, Fournier, John, Bermejo, Santos, Campbell, Melissa, Datta, Rupak, Dela Cruz, Charles S, Farhadian, Shelli F, Ko, Albert I, Iwasaki, Akiko, Grubaugh, Nathan D, Wilen, Craig B, Wyllie, Anne L

“…The expense of saliva collection devices designed to stabilize severe acute respiratory syndrome coronavirus 2 RNA is prohibitive to mass testing. However,…”
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CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus by Graziano, Vincent R, Walker, Forrest C, Kennedy, Elizabeth A, Wei, Jin, Ettayebi, Khalil, Strine, Madison S, Filler, Renata B, Hassan, Ebrahim, Hsieh, Leon L, Kim, Arthur S, Kolawole, Abimbola O, Wobus, Christiane E, Lindesmith, Lisa C, Baric, Ralph S, Estes, Mary K, Orchard, Robert C, Baldridge, Megan T, Wilen, Craig B

“…Murine norovirus (MNoV) is an important model of human norovirus (HNoV) and mucosal virus infection more broadly. Viral receptor utilization is a major…”
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DYRK1A promotes viral entry of highly pathogenic human coronaviruses in a kinase-independent manner by Strine, Madison S, Cai, Wesley L, Wei, Jin, Alfajaro, Mia Madel, Filler, Renata B, Biering, Scott B, Sarnik, Sylvia, Chow, Ryan D, Patil, Ajinkya, Cervantes, Kasey S, Collings, Clayton K, DeWeirdt, Peter C, Hanna, Ruth E, Schofield, Kevin, Hulme, Christopher, Konermann, Silvana, Doench, John G, Hsu, Patrick D, Kadoch, Cigall, Yan, Qin, Wilen, Craig B

“…Identifying host genes essential for Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has the potential to reveal novel drug targets and further…”
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A Novel Subcluster of Closely Related Bacillus Phages with Distinct Tail Fiber/Lysin Gene Combinations by Loney, Rachel E, Delesalle, Véronique A, Chaudry, Brianne E, Czerpak, Megan, Guffey, Alexandra A, Goubet-McCall, Leo, McCarty, Michael, Strine, Madison S, Tanke, Natalie T, Vill, Albert C, Krukonis, Greg P

“…Bacteriophages (phages) are the most numerous entities on Earth, but we have only scratched the surface of describing phage diversity. We isolated seven phages…”
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Introduction: Antimicrobial Resistance by Vanderwall, Morgan, Strine, Madison S

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CD300lf Conditional Knockout Mouse Reveals Strain-Specific Cellular Tropism of Murine Norovirus by Graziano, Vincent R, Alfajaro, Mia Madel, Schmitz, Cameron O, Filler, Renata B, Strine, Madison S, Wei, Jin, Hsieh, Leon L, Baldridge, Megan T, Nice, Timothy J, Lee, Sanghyun, Orchard, Robert C, Wilen, Craig B

“…Noroviruses are a leading cause of gastrointestinal infection in humans and mice. Understanding human norovirus (HuNoV) cell tropism has important implications…”
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Pharmacological disruption of mSWI/SNF complex activity restricts SARS-CoV-2 infection by Wei, Jin, Patil, Ajinkya, Collings, Clayton K., Alfajaro, Mia Madel, Liang, Yu, Cai, Wesley L., Strine, Madison S., Filler, Renata B., DeWeirdt, Peter C., Hanna, Ruth E., Menasche, Bridget L., Ökten, Arya, Peña-Hernández, Mario A., Klein, Jon, McNamara, Andrew, Rosales, Romel, McGovern, Briana L., Luis Rodriguez, M., García-Sastre, Adolfo, White, Kris M., Qin, Yiren, Doench, John G., Yan, Qin, Iwasaki, Akiko, Zwaka, Thomas P., Qi, Jun, Kadoch, Cigall, Wilen, Craig B.

“…Identification of host determinants of coronavirus infection informs mechanisms of viral pathogenesis and can provide new drug targets. Here we demonstrate…”
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Tuft-cell-intrinsic and -extrinsic mediators of norovirus tropism regulate viral immunity by Strine, Madison S., Alfajaro, Mia Madel, Graziano, Vincent R., Song, Jaewon, Hsieh, Leon L., Hill, Ryan, Guo, Jun, VanDussen, Kelli L., Orchard, Robert C., Baldridge, Megan T., Lee, Sanghyun, Wilen, Craig B.

“…Murine norovirus (MNoV) is a model for human norovirus and for interrogating mechanisms of viral tropism and persistence. We previously demonstrated that the…”
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Game over for RSV? by Strine, Madison S, Wilen, Craig B

“…Passive immunization with nirsevimab protects infants from severe RSV disease without impairing the immune response to natural infection…”
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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection by Wei, Jin, Alfajaro, Mia Madel, DeWeirdt, Peter C., Hanna, Ruth E., Lu-Culligan, William J., Cai, Wesley L., Strine, Madison S., Zhang, Shang-Min, Graziano, Vincent R., Schmitz, Cameron O., Chen, Jennifer S., Mankowski, Madeleine C., Filler, Renata B., Ravindra, Neal G., Gasque, Victor, de Miguel, Fernando J., Patil, Ajinkya, Chen, Huacui, Oguntuyo, Kasopefoluwa Y., Abriola, Laura, Surovtseva, Yulia V., Orchard, Robert C., Lee, Benhur, Lindenbach, Brett D., Politi, Katerina, van Dijk, David, Kadoch, Cigall, Simon, Matthew D., Yan, Qin, Doench, John G., Wilen, Craig B.

“…Identification of host genes essential for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection may reveal novel therapeutic targets and…”
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The KDM6A-KMT2D-p300 axis regulates susceptibility to diverse coronaviruses by mediating viral receptor expression by Wei, Jin, Alfajaro, Mia Madel, Cai, Wesley L, Graziano, Vincent R, Strine, Madison S, Filler, Renata B, Biering, Scott B, Sarnik, Sylvia A, Patel, Sonam, Menasche, Bridget L, Compton, Susan R, Konermann, Silvana, Hsu, Patrick D, Orchard, Robert C, Yan, Qin, Wilen, Craig B

“…Identification of host determinants of coronavirus infection informs mechanisms of pathogenesis and may provide novel therapeutic targets. Here, we demonstrate…”
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Murine Norovirus: Additional Protocols for Basic and Antiviral Studies by Wobus, Christiane E, Peiper, Amy M, McSweeney, Alice M, Young, Vivienne L, Chaika, Maryna, Lane, Miranda Sophie, Lingemann, Marit, Deerain, Joshua M, Strine, Madison S, Alfajaro, Mia Madel, Helm, Emily W, Karst, Stephanie M, Mackenzie, Jason M, Taube, Stefan, Ward, Vernon K, Wilen, Craig B

“…Murine norovirus (MNV) is a positive-sense, plus-stranded RNA virus in the Caliciviridae family. Viruses in this family replicate in the intestine and are…”
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Comparative Genomics of Six Lytic Bacillus subtilis Phages from the Southwest United States by Vill, Albert C, Delesalle, Véronique A, Tomko, Brianne E, Lichty, Katherine B, Strine, Madison S, Guffey, Alexandra A, Burton, Elizabeth A, Tanke, Natalie T, Krukonis, Greg P

“…Background: Despite their importance to microbial dynamics involving Bacillus subtilis , we have a limited understanding of the diversity of phages that can…”
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Intestinal tuft cell immune privilege enables norovirus persistence by Strine, Madison S, Fagerberg, Eric, Darcy, Patrick W, Barrón, Gabriel M, Filler, Renata B, Alfajaro, Mia Madel, D'Angelo-Gavrish, Nicole, Wang, Fang, Graziano, Vincent R, Menasché, Bridget L, Damo, Martina, Wang, Ya-Ting, Howitt, Michael R, Lee, Sanghyun, Joshi, Nikhil S, Mucida, Daniel, Wilen, Craig B

“…The persistent murine norovirus strain MNV is a model for human norovirus and enteric viral persistence. MNV causes chronic infection by directly infecting…”
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Tuft cells are key mediators of interkingdom interactions at mucosal barrier surfaces by Madison S. Strine, Craig B. Wilen

“…Although tuft cells were discovered over 60 years ago, their functions have long been enigmatic, especially in human health. Nonetheless, tuft cells have…”
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Tuft cell tropism enables norovirus evasion of CD8+ T cells and viral persistence by Strine, Madison S, Filler, Renata, Alfajaro, Mia Madel, Damo, Martina, Gonzalez, David, Haberman, Ann Marie, Joshi, Nikhil, Wilen, Craig

“…Abstract Human norovirus (HNV) is a leading cause of viral gastroenteritis. Infection fails to elicit durable immunity and can cause chronic asymptomatic…”
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A Novel Subcluster of Closely Related IBacillus/I Phages with Distinct Tail Fiber/Lysin Gene Combinations by Loney, Rachel E, Delesalle, Véronique A, Chaudry, Brianne E, Czerpak, Megan, Guffey, Alexandra A, Goubet-McCall, Leo, McCarty, Michael, Strine, Madison S, Tanke, Natalie T, Vill, Albert C, Krukonis, Greg P

“…Bacteriophages (phages) are the most numerous entities on Earth, but we have only scratched the surface of describing phage diversity. We isolated seven…”
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