Search Results - "Striker, G E"

Combined AGE inhibition and ACEi decreases the progression of established diabetic nephropathy in B6 db/db mice by Zheng, F., Zeng, Y.-j., Plati, A.-R., Elliot, S.J., Berho, M., Potier, M., Striker, L.J., Striker, G.E.

“…The accumulation of advanced glycation end products (AGE) is a key factor in diabetic nephropathy (DN). Pyridoxamine inhibits AGE formation and protects…”
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Prevention of diabetic renal disease with special reference to microalbuminuria by Mogensen, C E, Keane, W F, Bennett, P H, Jerums, G, Parving, H H, Passa, P, Steffes, M W, Striker, G E, Viberti, G C

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Glomerulosclerosis is transmitted by bone marrow-derived mesangial cell progenitors by Cornacchia, F, Fornoni, A, Plati, A R, Thomas, A, Wang, Y, Inverardi, L, Striker, L J, Striker, G E

“…We found that ROP Os/+ (Os/+) mice had diffuse glomerulosclerosis and glomerular hypertrophy and that their mesangial cells (the vascular smooth muscle cells…”
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IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: implications for diabetic nephropathy by LUPIA, E, ELLIOT, S. J, LENZ, O, ZHENG, F, HATTORI, M, STRIKER, G. E, STRIKER, L. J

“…IGF-1 decreases collagen degradation in diabetic NOD mesangial cells: implications for diabetic nephropathy. E Lupia , S J Elliot , O Lenz , F Zheng , M…”
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Receptor-Specific Increase in Extracellular Matrix Production in Mouse Mesangial Cells by Advanced Glycosylation End Products is Mediated Via Platelet-Derived Growth Factor by Doi, Toshio, Vlassara, Helen, Kirstein, Martina, Yamada, Yoshihiko, Striker, Gary E., Striker, Liliane J.

“…Renal disease is one of the most common and severe complications of diabetes mellitus. The hallmark of the disease, glomerulosclerosis, is characterized by an…”
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Advanced glycation end products up-regulate gene expression found in diabetic glomerular disease by Yang, Chih-Wei, Vlassara, Helen, Peten, Emmanuel P., He, Ci-Jiang, Striker, Gary E., Striker, Liliane J.

“…Several lines of evidence suggest that the excessive accumulation of extracellular matrix in the glomeruli of diabetic kidneys may be due to reactive…”
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Managing chronic inflammation in the aging diabetic patient with CKD by diet or sevelamer carbonate: a modern paradigm shift by Vlassara, H, Cai, W, Chen, X, Serrano, E J, Shobha, M S, Uribarri, J, Woodward, M, Striker, G E

“…The maintenance of normal metabolism and body defenses depends on the balance between cellular antioxidant and anti-inflammatory factors. This balance can be…”
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Gender-specific effects of endogenous testosterone: Female α-estrogen receptor-deficient C57Bl/6J mice develop glomerulosclerosis by Elliot, S.J., Berho, M., Korach, K., Doublier, S., Lupia, E., Striker, G.E., Karl, M.

“…Young female mice on a C57Bl/6J (B6) background are considered glomerulosclerosis (GS)-resistant but aging B6 mice develop mild GS. Estrogen deficiency…”
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Early development of the renal lesions in infantile cystinosis by Mahoney, C P, Striker, G E

“…To identify the early renal lesions in cystinosis, including whether the "swan neck" deformity of the proximal tubule is a congenital or an acquired lesion, we…”
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Mesangial cell turnover: effect of heparin and peptide growth factors by Striker, L J, Peten, E P, Elliot, S J, Doi, T, Striker, G E

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Transforming growth factor-beta. Murine glomerular receptors and responses of isolated glomerular cells by MacKay, K, Striker, L J, Stauffer, J W, Doi, T, Agodoa, L Y, Striker, G E

“…Proliferation of resident glomerular cells and the accumulation of mesangial matrix are histologic abnormalities which are observed in the course of many…”
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Progressive glomerulosclerosis develops in transgenic mice chronically expressing growth hormone and growth hormone releasing factor but not in those expressing insulinlike growth factor-1 by Doi, T, Striker, LJ, Quaife, C, Conti, FG, Palmiter, R, Behringer, R, Brinster, R, Striker, GE

“…An increase in glomerular size occurs in normal maturation after subtotal renal ablation and disease states such as diabetes mellitus. The role that growth…”
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Strain differences rather than hyperglycemia determine the severity of glomerulosclerosis in mice by Zheng, Feng, Striker, Gary E., Esposito, Ciro, Lupia, Enrico, Striker, Liliane J.

“…Strain differences rather than hyperglycemia determine the severity of glomerulosclerosis in mice. We reported that ROP, but not C57, mice were prone to…”
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Glomerular cell culture by Striker, G E, Striker, L J

“…Glomerular cell culture has now become a widely used research technique. At the present time procedures are available to obtain isolated glomeruli from nearly…”
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Therapeutic uses of heparinoids in renal disease patients by STRIKER, G. E

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Nature and Severity of the Glomerular Response to Nephron Reduction Is Strain-Dependent in Mice by Esposito, Ciro, He, Ci-Jiang, Striker, Gary E., Zalups, Rudolfs K., Striker, Liliane J.

“…Nephron reduction is an important factor in the development of glomerulosclerosis. In a study of the oligosyndactyly (Os) mutation that causes a congenital 50%…”
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Administration of AGEs in vivo induces extracellular matrix gene expression by STRIKER, L. J, STRIKER, G. E

“…The role that advanced glycosylation end-products (AGEs) may play in the development of diabetic nephropathy is still not completely understood. In order to…”
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N-phenacylthiazolium bromide decreases renal and increases urinary advanced glycation end products excretion without ameliorating diabetic nephropathy in C57BL/6 mice by Schwedler, S. B., Verbeke, P., Bakala, H., Weiss, M. F., Vilar, J., Depreux, P., Fourmaintraux, E., Striker, L. J., Striker, G. E.

“…Summary Aims  Advanced glycation end products (AGE), which form from the non‐enzymatic reaction of proteins and sugars, have been implicated in the…”
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Glomerulosclerosis at both early and late stages is associated with increased cell turnover in mice transgenic for growth hormone by Pesce, C M, Striker, L J, Peten, E, Elliot, S J, Striker, G E

“…The evolution of glomerulosclerosis consists of a progressive increase in mesangial matrix with gradual glomerular obliteration. The sclerotic process is…”
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TNF-alpha and IL-1 alpha induce mannose receptors and apoptosis in glomerular mesangial but not endothelial cells by Liu, Z H, Striker, G E, Stetler-Stevenson, M, Fukushima, P, Patel, A, Striker, L J

“…The macrophage mannose receptor, a carbohydrate-binding membrane protein, mediates endocytosis and phagocytosis. This study was undertaken to determine whether…”
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