Search Results - "Strik, Herwig M."
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Glycobiology in malignant gliomas: expression and functions of galectins and possible therapeutic options
Published in Current pharmaceutical biotechnology (01-09-2012)“…Malignant gliomas, the most common malignant primary brain tumors, have a deleterious clinical prognosis of approximately 12 months in unselected series. The…”
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2
Chloroethylating nitrosoureas in cancer therapy: DNA damage, repair and cell death signaling
Published in Biochimica et biophysica acta. Reviews on cancer (01-08-2017)“…Chloroethylating nitrosoureas (CNU), such as lomustine, nimustine, semustine, carmustine and fotemustine are used for the treatment of malignant gliomas, brain…”
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3
Immune Cell Infiltration of Intrinsic and Metastatic Intracranial Tumours
Published in Anticancer research (01-01-2004)“…Background: Immune escape is one prerequisite for the formation of neoplasms that is reflected by the pattern of immune cell infiltration. Abundant monocytic…”
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Temozolomide Dosing Regimens for Glioma Patients
Published in Current neurology and neuroscience reports (01-06-2012)“…Even in modern times of high-precision brain surgery and irradiation, malignant gliomas belong to the deadliest types of cancer. Due to a marked primary and…”
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5
Models of Monocytic Invasion into Glioma Cell Aggregates
Published in Anticancer research (01-03-2006)“…Background: In order to investigate why human gliomas are abundantly infiltrated by monocytic cells without signs of antitumor activity, experimental models…”
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6
Clinical Response Following Adjuvant Temozolomide in a Patient with Primary Cerebral Lymphoma
Published in Anticancer research (01-11-2004)“…A 69-year-old female patient was treated for primary CNS-lymphoma (PCNSL) starting from August 2002. As her general condition allowed no high-dose methotrexate…”
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Cerebrospinal fluid ferritin--unspecific and unsuitable for disease monitoring
Published in Neurologia i neurochirurgia polska (01-01-2014)“…Subarachnoid hemorrhage is sometimes difficult to diagnose radiologically. Cerebrospinal fluid (CSF) ferritin has been proposed to be highly specific and…”
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Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11β-hydroxysteroid dehydrogenases in multiple sclerosis: Implications for lesion pathogenesis
Published in Brain, behavior, and immunity (01-08-2010)“…Abstract Relapses during multiple sclerosis (MS) are treated by administration of exogenous corticosteroids. However, little is known about the bioavailability…”
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9
Galectin-1 expression in human glioma cells : Modulation by ionizing radiation and effects on tumor cell proliferation and migration
Published in Oncology reports (01-08-2007)“…Galectins are evolutionarily conserved beta-galactoside-binding lectins which recognize specific glycoconjugates on the cell surface and the extracellular…”
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10
Localization of endostatin in rat and human gliomas
Published in Cancer (01-03-2001)“…BACKGROUND Endostatin is a potent inhibitor of endothelial cell proliferation, angiogenesis, and tumor growth. Its occurrence and localization has not yet been…”
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Galectin-3: cellular distribution and correlation with WHO-grade in human gliomas
Published in Journal of neuro-oncology (01-05-2001)“…In order to elucidate the reason for conflicting results that have been published previously on galectin-3 expression in human gliomas, we used single labeling…”
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12
Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11b-hydroxysteroid dehydrogenases in multiple sclerosis: Implications for lesion pathogenesis
Published in Brain, behavior, and immunity (01-08-2010)“…Relapses during multiple sclerosis (MS) are treated by administration of exogenous corticosteroids. However, little is known about the bioavailability of…”
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13
Rechallenge with temozolomide with different scheduling is effective in recurrent malignant gliomas
Published in Molecular medicine reports (01-11-2008)“…Treatment of recurrent malignant glioma, which has a poor patient prognosis, has not been standardised. Moreover, it is unclear whether repeated treatment with…”
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14
Three-dimensional reconstruction and volumetry of intracranial haemorrhage and its mass effect
Published in Neuroradiology (01-06-2005)“…Intracerebral haemorrhage still causes considerable disability and mortality. The studies on conservative and operative management are inconclusive, probably…”
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15
Reduced cortisol levels in cerebrospinal fluid and differential distribution of 11beta-hydroxysteroid dehydrogenases in multiple sclerosis: implications for lesion pathogenesis
Published in Brain, behavior, and immunity (01-08-2010)“…Relapses during multiple sclerosis (MS) are treated by administration of exogenous corticosteroids. However, little is known about the bioavailability of…”
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16
The impact of progesterone receptor expression on relapse in the long-term clinical course of 93 benign meningiomas
Published in In vivo (Athens) (01-07-2002)“…Previous clinicopathological observations have pointed towards an impact of progesterone receptor (PgR) expression on the clinical course of meningiomas…”
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