Search Results - "Stride, Eleanor P."
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Microbubble-laden aerosols improve post-nasal aerosol penetration efficiency in a preterm neonate model
Published in International journal of pharmaceutics (05-12-2024)“…[Display omitted] Nebulized lung surfactant therapy has been a neonatology long-pursued goal. Nevertheless, many clinical trials have yet to show a clear…”
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Behavior of Microbubbles on Air–Aqueous Interfaces
Published in Langmuir (05-11-2024)“…Animal-derived lung surfactants have saved millions of lives of preterm neonates with neonatal Respiratory Distress Syndrome (nRDS). However, a replacement for…”
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Modelling Drug Delivery to the Small Airways: Optimization Using Response Surface Methodology
Published in Pharmaceutical research (01-06-2024)“…Aim The aim of this in silico study was to investigate the effect of particle size, flow rate, and tidal volume on drug targeting to small airways in patients…”
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In silico investigation of the effect of particle diameter on deposition uniformity in pulmonary drug delivery
Published in Aerosol science and technology (03-04-2023)“…Systemic drug delivery via the pulmonary route has a critical limitation because dose uniformity is strongly dependent upon patient inhalation technique. The…”
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Beyond automatic medical image segmentation-the spectrum between fully manual and fully automatic delineation
Published in Physics in medicine & biology (21-06-2022)“…Semi-automatic and fully automatic contouring tools have emerged as an alternative to fully manual segmentation to reduce time spent contouring and to increase…”
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Deep learning-assisted interactive contouring of lung cancer: Impact on contouring time and consistency
Published in Radiotherapy and oncology (01-11-2024)“…•A Deep Learning (DL)-assisted contouring tool was evaluated and compared to standard manual contouring when delineating non-small cell lung cancer cases.•Use…”
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Interactive contouring through contextual deep learning
Published in Medical physics (Lancaster) (01-06-2021)“…Purpose To investigate a deep learning approach that enables three‐dimensional (3D) segmentation of an arbitrary structure of interest given a user provided…”
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Protein-Decorated Microbubbles for Ultrasound-Mediated Cell Surface Manipulation
Published in ACS applied bio materials (18-12-2023)“…Delivering cargo to the cell membranes of specific cell types in the body is a major challenge for a range of treatments, including immunotherapy. This study…”
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But I did science so I wouldn’t have to write essays
Published in The Journal of the Acoustical Society of America (01-03-2024)“…A dislike of writing, sometimes bordering on a phobia, seems to be a common experience for many science students and indeed practising scientists. This…”
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Jack of all trades: Challenges and opportunities for mentoring in interdisciplinary research
Published in The Journal of the Acoustical Society of America (01-03-2023)“…Biomedical acoustics spans a particularly broad range of disciplines from neuroscience to quantum physics and everything in between. While this diversity is…”
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Probing the mechanisms of sonodynamic therapy
Published in The Journal of the Acoustical Society of America (01-04-2022)“…Drugs that can be activated by a physical stimulus at a target site offer great potential for limiting toxic side effects, e.g., in cancer therapy. In…”
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Quantifying the role of microstreaming in sonoporation
Published in The Journal of the Acoustical Society of America (01-04-2022)“…Cavitation microstreaming has been identified as an important mechanism underpinning sonoporation. The reported evidence includes experimental observation of…”
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Non-equilibrium activation dynamics of superheated phase-change contrast agents
Published in The Journal of the Acoustical Society of America (01-03-2024)“…Phase-change contrast agents, such as superheated perfluorocarbon droplets, potentially offer exciting new opportunities in diagnostic and therapeutic…”
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Modulating ultrasound field phase and amplitude using foam gratings as an alternative to acoustic lenses
Published in The Journal of the Acoustical Society of America (01-03-2024)“…There is an increasing number of applications for therapeutic ultrasound, including high intensity focused ultrasound surgery, neuromodulation and drug…”
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Scaleable production of microbubbles using an ultrasound-modulated microfluidic device
Published in The Journal of the Acoustical Society of America (01-10-2020)“…Surfactant-coated gas microbubbles are widely used as contrast agents in ultrasound imaging and increasingly for therapeutic applications. It has been shown…”
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Theoretical and experimental investigation of the vaporisation of superheated perfluorocarbon droplets
Published in The Journal of the Acoustical Society of America (01-03-2023)“…Acoustically activatable “nano”droplets consisting of superheated liquid perfluorocarbons have been investigated for both imaging and therapeutic applications…”
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Exploration of ultrasound-mediated microbubble-cell membrane interactions using novel protein-loaded microbubbles and their role in immunomodulation
Published in The Journal of the Acoustical Society of America (01-04-2022)“…The immune response is governed by the dynamic spatiotemporal regulation of signalling proteins at the interface between immune cells and their targets. The…”
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Foam gratings as an alternative to customised acoustic lenses
Published in The Journal of the Acoustical Society of America (01-10-2021)“…Tissue inhomogeneity can affect the accuracy with which ultrasound can be focused into the body. In existing clinical systems, phase corrections are typically…”
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Simultaneous plane-wave and ultra high-speed imaging of acoustic droplet vaporization
Published in The Journal of the Acoustical Society of America (01-03-2024)“…Super-heated sub-micrometre perfluorocarbon droplets have been shown to offer advantages over microbubbles for ultrasound localization microscopy (ULM). These…”
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