Search Results - "Strickland, Laura"
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Neuropilin-1 expression in cancer and development
Published in The Journal of pathology (01-01-2012)“…Neuropilin (NRP)‐1 is a co‐receptor for vascular endothelial growth factor (VEGF). Preclinical data suggest that blockade of NRP1 suppresses tumour growth by…”
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The impact of Pompe disease on smooth muscle: a review
Published in Journal of Smooth Muscle Research (2018)“…Pompe disease (OMIM 232300) is an autosomal recessive disorder caused by mutations in the gene encoding acid α-glucosidase (GAA) (EC 3.2.1.20), the enzyme…”
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Cancer-associated SMARCAL1 loss-of-function mutations promote alternative lengthening of telomeres and tumorigenesis in telomerase-negative glioblastoma cells
Published in Neuro-oncology (Charlottesville, Va.) (05-09-2023)“…Abstract Background Telomere maintenance mechanisms are required to enable the replicative immortality of malignant cells. While most cancers activate the…”
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Glycogen accumulation in smooth muscle of a Pompe disease mouse model
Published in Journal of Smooth Muscle Research (2021)“…Pompe disease is a lysosomal storage disease caused by mutations within the GAA gene, which encodes acid α-glucosidase (GAA)—an enzyme necessary for lysosomal…”
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Accumulation of pathological Ataxin‐7 in the medulla leads to hypoglossal (XII) motor unit pathology
Published in The FASEB journal (01-05-2022)“…SCA7 is an autosomal dominant neurological disorder caused by a deleterious CAG repeat expansion in the coding region of the ataxin‐7 gene on chromosome 3…”
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Motor axonopathies in a mouse model of Duchenne muscular dystrophy
Published in Scientific reports (02-06-2020)“…Duchenne muscular dystrophy (DMD) is a fatal neuromuscular disease caused by deleterious mutations in the DMD gene which encodes the dystrophin protein…”
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What's new and what's next for gene therapy in Pompe disease?
Published in Expert opinion on biological therapy (02-09-2022)“…Pompe disease is an autosomal recessive disorder caused by a deficiency of acid-α-glucosidase (GAA), an enzyme responsible for hydrolyzing lysosomal glycogen…”
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Respiratory dysfunction in a mouse model of spinocerebellar ataxia type 7
Published in Disease models & mechanisms (01-07-2021)“…Spinocerebellar ataxia type 7 (SCA7) is an autosomal-dominant neurodegenerative disorder caused by a CAG repeat expansion in the coding region of the ataxin-7…”
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X-linked SBMA model mice display relevant non-neurological phenotypes and their expression of mutant androgen receptor protein in motor neurons is not required for neuromuscular disease
Published in Acta neuropathologica communications (02-06-2023)“…X-linked spinal and bulbar muscular atrophy (SBMA; Kennedy's disease) is a rare neuromuscular disorder characterized by adult-onset proximal muscle weakness…”
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Plant macrofossil data for 48-0 ka in the USGS North American Packrat Midden Database, version 5.0
Published in Scientific data (12-01-2024)“…Plant macrofossils from packrat ( Neotoma spp.) middens provide direct evidence of past vegetation changes in arid regions of North America. Here we describe…”
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Respiratory pathology in the Optn-/- mouse model of Amyotrophic Lateral Sclerosis
Published in Respiratory physiology & neurobiology (01-11-2020)“…•The optineurin-deficient mouse model (Optn-/-) exhibits respiratory insufficiency during a hypoxic and hypercapnic challenge.•Motor neuron loss is evident in…”
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Neotectonic Mapping of Puerto Rico
Published in Seismica (11-09-2024)“…Puerto Rico is part of the Puerto Rico-Virgin Islands microplate, along the Caribbean–North American plate boundary between the Puerto Rico trench subduction…”
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Respiratory neuropathology in spinocerebellar ataxia type 7
Published in JCI insight (18-07-2024)“…Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurological disorder caused by deleterious CAG repeat expansion in the coding region of the…”
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Preclinical evaluation of carcinoembryonic cell adhesion molecule (CEACAM) 6 as potential therapy target for pancreatic adenocarcinoma
Published in The Journal of pathology (01-07-2009)“…Despite the availability of new targeted therapies, ductal pancreatic adenocarcinoma continues to carry a poor prognosis. Carcinoembryonic antigen-related cell…”
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Neuropilin-2 expression in cancer
Published in Histopathology (01-09-2012)“…Jubb A M, Sa S M, Ratti N, Strickland L A, Schmidt M, Callahan C A & Koeppen H (2012) Histopathology 61, 340–349 Neuropilin‐2 expression in cancer Aims: …”
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Plasmalemmal vesicle-associated protein (PLVAP) is expressed by tumour endothelium and is upregulated by vascular endothelial growth factor-A (VEGF)
Published in The Journal of pathology (01-08-2005)“…Vascular endothelial growth factor‐A (VEGF) is an important regulator of vascular permeability. In preclinical studies, VEGF induces endothelial fenestrations…”
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Comments on plasmalemmal vesicle associated protein-1 as a novel marker implicated in brain tumor angiogenesis
Published in Clinical cancer research (15-04-2006)Get full text
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The Danielson Evaluation System in Two Mid-South High Schools: A Case Study
Published 2014“…The purpose of this study is to answer the question: How do pilot users of the Danielson Evaluation System perceive this model in two mid-south high schools?…”
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Dissertation -
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Phrenic and Hypoglossal motor unit pathology in a Spinocerebellar ataxia type 7 mouse model
Published in The FASEB journal (01-05-2021)“…Spinocerebellar ataxia type 7 (SCA7) is an autosomal dominant neurodegenerative disorder caused by a deleterious CAG repeat expansion in the coding region of…”
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Journal Article