Search Results - "Strickland, Jenna D."

Concentration–response evaluation of ToxCast compounds for multivariate activity patterns of neural network function by Kosnik, Marissa B., Strickland, Jenna D., Marvel, Skylar W., Wallis, Dylan J., Wallace, Kathleen, Richard, Ann M., Reif, David M., Shafer, Timothy J.

“…The US Environmental Protection Agency’s ToxCast program has generated toxicity data for thousands of chemicals but does not adequately assess potential…”
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Assaying Spontaneous Network Activity and Cellular Viability Using Multi-well Microelectrode Arrays by Brown, Jasmine P, Lynch, Brittany S, Curry-Chisolm, Itaevia M, Shafer, Timothy J, Strickland, Jenna D

“…Microelectrode array (MEA) technology is a neurophysiological method that allows for the spontaneous measure of activity in neural cultures and determination…”
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Assaying Spontaneous Network Activity and Cellular Viability Using Multi-Well Microelectrode Arrays by Choo, Seline S, Keever, Jackson Y, Brown, Jasmine, Strickland, Jenna D, Shafer, Timothy J

“…Microelectrode array (MEA) technology is a neurophysiological method that allows for the measurement of spontaneous or evoked neural activity to determine…”
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Screening the ToxCast phase II libraries for alterations in network function using cortical neurons grown on multi-well microelectrode array (mwMEA) plates by Strickland, Jenna D., Martin, Matthew T., Richard, Ann M., Houck, Keith A., Shafer, Timothy J.

“…Methods are needed for rapid screening of environmental compounds for neurotoxicity, particularly ones that assess function. To demonstrate the utility of…”
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A multiplexed assay for determination of neurotoxicant effects on spontaneous network activity and viability from microelectrode arrays by Wallace, Kathleen, Strickland, Jenna D., Valdivia, Pablo, Mundy, William R., Shafer, Timothy J.

“…Microelectrode array (MEA) recordings are increasingly being used as an in vitro method to detect and characterize the ability of drugs, chemicals and…”
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Modulation of macrophage phenotype to treat liver fibrosis-Current approaches and future possibilities by Strickland, Jenna D, Copple, Bryan L

“…Liver fibrosis is a leading cause of death worldwide, accounting for approximately 2 million deaths annually. Despite its wide prevalence, there are currently…”
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Effects of an environmentally-relevant mixture of pyrethroid insecticides on spontaneous activity in primary cortical networks on microelectrode arrays by Johnstone, Andrew F.M., Strickland, Jenna D., Crofton, Kevin M, Gennings, Chris, Shafer, Timothy J.

“…•Effects of 5 pyrethroids on electrical activity were examined in neural networks.•Permethrin slightly increased network mean firing rate (MFR).•Deltamethrin,…”
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In vitro screening of metal oxide nanoparticles for effects on neural function using cortical networks on microelectrode arrays by Strickland, Jenna D., Lefew, William R., Crooks, James, Hall, Diana, Ortenzio, Jayna NR, Dreher, Kevin, Shafer, Timothy J.

“…Nanoparticles (NPs) may translocate to the brain following inhalation or oral exposures, yet higher throughput methods to screen NPs for potential…”
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Differential regulation of hepatic physiology and injury by the TAM receptors Axl and Mer by Zagórska, Anna, Través, Paqui G, Jiménez-García, Lidia, Strickland, Jenna D, Oh, Joanne, Tapia, Francisco J, Mayoral, Rafael, Burrola, Patrick, Copple, Bryan L, Lemke, Greg

“…Genome-wide association studies have implicated the TAM receptor tyrosine kinase (RTK) Mer in liver disease, yet our understanding of the role that Mer and its…”
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In Vitro Screening of Silver Nanoparticles and Ionic Silver using Neural Networks Yields Differential Effects on Spontaneous Activity and Pharmacological Responses by Strickland, Jenna D, LeFew, William R, Crooks, James, Hall, Diana, Ortenzio, Jayna N.R, Dreher, Kevin, Shafer, Timothy J

“…Abstract Silver nanoparticles (AgNPs) are used in a wide range of consumer and medical products because of their antimicrobial and antifungal properties, and…”
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Upregulation of Stromal‐derived Factor‐1 by Hypoxia Requires Hypoxia‐Inducible Factor‐1α and Transforming Growth Factor‐1 by Strickland, Jenna D., Garrison, Dominique, Copple, Bryan

“…Following both acute and chronic liver injury, expression of the chemokine stromal‐derived factor‐1 (SDF‐1), or CxCl12, is upregulated and plays a vital role…”
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Failed Phenotype Switching by Hepatic Macrophages Produces Persistent Inflammation in Acute Liver Failure by Strickland, Jenna D, Roth, Katherine J, Copple, Bryan L

“…Acute liver failure remains a significant health problem with a high rate of mortality. Studies have revealed that acetaminophen‐induced acute liver failure…”
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