Search Results - "Strese, Sara"

Effects of hypoxia on human cancer cell line chemosensitivity by Strese, Sara, Fryknäs, Mårten, Larsson, Rolf, Gullbo, Joachim

“…Environment inside even a small tumor is characterized by total (anoxia) or partial oxygen deprivation, (hypoxia). It has been shown that radiotherapy and some…”
Get full text

In vitro and in vivo activity of melflufen (J1)in lymphoma by Delforoush, Maryam, Strese, Sara, Wickström, Malin, Larsson, Rolf, Enblad, Gunilla, Gullbo, Joachim

“…Melphalan has been used in the treatment of various hematologic malignancies for almost 60 years. Today it is part of standard therapy for multiple myeloma and…”
Get full text

In vitro and in vivo anti-leukemic activity of the peptidase-potentiated alkylator melflufen in acute myeloid leukemia by Strese, Sara, Hassan, Saadia Bashir, Velander, Ebba, Haglund, Caroline, Höglund, Martin, Larsson, Rolf, Gullbo, Joachim

“…The novel aminopeptidase potentiated alkylating agent melflufen, was evaluated for activity in acute myeloid leukemia in a range of in vitro models, as well as…”
Get full text

The novel alkylating prodrug melflufen (J1) inhibits angiogenesis in vitro and in vivo by Strese, Sara, Wickström, Malin, Fuchs, Peder Fredlund, Fryknäs, Mårten, Gerwins, Pär, Dale, Tim, Larsson, Rolf, Gullbo, Joachim

“…Aminopeptidase N (APN) has been reported to have a functional role in tumor angiogenesis and repeatedly reported to be over-expressed in human tumors. The…”
Get full text

Mechanistic characterization of a copper containing thiosemicarbazone with potent antitumor activity by Karlsson, Henning, Fryknäs, Mårten, Strese, Sara, Gullbo, Joachim, Westman, Gunnar, Bremberg, Ulf, Sjöblom, Tobias, Pandzic, Tatjana, Larsson, Rolf, Nygren, Peter

“…The thiosemicarbazone CD 02750 (VLX50) was recently reported as a hit compound in a phenotype-based drug screen in primary cultures of patient tumor cells. We…”
Get full text

Preclinical activity of melflufen (J1) in ovarian cancer by Carlier, Charlotte, Strese, Sara, Viktorsson, Kristina, Velander, Ebba, Nygren, Peter, Uustalu, Maria, Juntti, Therese, Lewensohn, Rolf, Larsson, Rolf, Spira, Jack, De Vlieghere, Elly, Ceelen, Wim P, Gullbo, Joachim

“…Ovarian cancer carries a significant mortality. Since symptoms tend to be minimal, the disease is often diagnosed when peritoneal metastases are already…”
Get full text