Search Results - "Streltsova, Maria A"

Multiple Actions of Telomerase Reverse Transcriptase in Cell Death Regulation by Palamarchuk, Anastasia I, Kovalenko, Elena I, Streltsova, Maria A

“…Telomerase reverse transcriptase (TERT), a core part of telomerase, has been known for a long time only for its telomere lengthening function by reverse…”
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Analysis of NK cell clones obtained using interleukin-2 and gene-modified K562 cells revealed the ability of "senescent" NK cells to lose CD57 expression and start expressing NKG2A by Streltsova, Maria A, Erokhina, Sofya A, Kanevskiy, Leonid M, Lee, Dean A, Telford, William G, Sapozhnikov, Alexander M, Kovalenko, Elena I

“…In this work, we analyzed the phenotype and growth of human NK cell clones obtained by the stimulation of individual NK cells with IL-2 and gene-modified K562…”
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The Biological Role and Therapeutic Potential of NK Cells in Hematological and Solid Tumors by Velichinskii, Rodion A, Streltsova, Maria A, Kust, Sofya A, Sapozhnikov, Alexander M, Kovalenko, Elena I

“…NK cells are an attractive target for cancer immunotherapy due to their potent antitumor activity. The main advantage of using NK cells as cytotoxic effectors…”
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HLA-DR-Positive NK Cells Expand in Response to Mycobacterium Tuberculosis Antigens and Mediate Mycobacteria-Induced T Cell Activation by Kust, Sofya A, Streltsova, Maria A, Panteleev, Alexander V, Karpina, Natalya L, Lyadova, Irina V, Sapozhnikov, Alexander M, Kovalenko, Elena I

“…NK cells play an important role in the control of tuberculosis infection: they are not only able to kill the infected cells, but also control the activity of…”
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HLA-DR Expression in Natural Killer Cells Marks Distinct Functional States, Depending on Cell Differentiation Stage by Kust, Sofya A, Ustiuzhanina, Maria O, Streltsova, Maria A, Shelyakin, Pavel V, Kryukov, Maxim A, Lutsenko, Gennady V, Sudarikova, Anna V, Merzlyak, Ekaterina M, Britanova, Olga V, Sapozhnikov, Alexandr M, Kovalenko, Elena I

“…HLA-DR-positive NK cells, found in both healthy individuals and patients with different inflammatory diseases, are characterized as activated cells. However,…”
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The hTERT and iCasp9 Transgenes Affect EOMES and T-BET Levels in NK Cells and the Introduction of Both Genes Improves NK Cell Proliferation in Response to IL2 and IL15 Stimulation by Palamarchuk, Anastasia I, Kovalenko, Elena I, Streltsova, Maria A

“…The NK cell exhaustion state evolving during extensive and prolonged cultivation is still one of the limitations of NK cell approaches. In this research, we…”
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Reduced Immunosenescence of Peripheral Blood T Cells in Parkinson's Disease with CMV Infection Background by Vavilova, Julia D, Boyko, Anna A, Ponomareva, Natalya V, Fokin, Vitaly F, Fedotova, Ekaterina Y, Streltsova, Maria A, Kust, Sofya A, Grechikhina, Maria V, Bril, Ekaterina V, Zimnyakova, Olga S, Kovalenko, Elena I, Sapozhnikov, Alexander M

“…Immunosenescence is a process of remodeling the immune system under the influence of chronic inflammation during aging. Parkinson's disease (PD) is a common…”
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Coordinated Loss and Acquisition of NK Cell Surface Markers Accompanied by Generalized Cytokine Dysregulation in COVID-19 by Ustiuzhanina, Maria O, Vavilova, Julia D, Boyko, Anna A, Streltsova, Maria A, Kust, Sofya A, Kanevskiy, Leonid M, Sapozhnikov, Alexander M, Iskhakov, Rustam N, Gubernatorova, Ekaterina O, Drutskaya, Marina S, Bychinin, Mikhail V, Zhukova, Oksana A, Novikova, Oksana N, Sotnikova, Anna G, Yusubalieva, Gaukhar M, Baklaushev, Vladimir P, Kovalenko, Elena I

“…Coronavirus disease 2019 (COVID-19), caused by the SARS-CoV-2 virus, is accompanied by a dysregulated immune response. In particular, NK cells, involved in the…”
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Alterations in the CD56 - and CD56 + T Cell Subsets during COVID-19 by Vavilova, Julia D, Ustiuzhanina, Maria O, Boyko, Anna A, Streltsova, Maria A, Kust, Sofya A, Kanevskiy, Leonid M, Iskhakov, Rustam N, Sapozhnikov, Alexander M, Gubernatorova, Ekaterina O, Drutskaya, Marina S, Bychinin, Mikhail V, Novikova, Oksana N, Sotnikova, Anna G, Yusubalieva, Gaukhar M, Baklaushev, Vladimir P, Kovalenko, Elena I

“…The effectiveness of the antiviral immune response largely depends on the activation of cytotoxic T cells. The heterogeneous group of functionally active T…”
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Increased Susceptibility of the CD57 - NK Cells Expressing KIR2DL2/3 and NKG2C to iCasp9 Gene Retroviral Transduction and the Relationships with Proliferative Potential, Activation Degree, and Death Induction Response by Palamarchuk, Anastasia I, Alekseeva, Nadezhda A, Streltsova, Maria A, Ustiuzhanina, Maria O, Kobyzeva, Polina A, Kust, Sofya A, Grechikhina, Maria V, Boyko, Anna A, Shustova, Olga A, Sapozhnikov, Alexander M, Kovalenko, Elena I

“…Nowadays, the use of genetically modified NK cells is a promising strategy for cancer immunotherapy. The additional insertion of genes capable of inducing cell…”
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Surface NKG2C Identifies Differentiated αβT-Cell Clones Expanded in Peripheral Blood by Kovalenko, Elena I, Zvyagin, Ivan V, Streltsova, Maria A, Mikelov, Artem I, Erokhina, Sofya A, Telford, William G, Sapozhnikov, Alexander M, Lebedev, Yury B

“…T cells that express CD56 in peripheral blood of healthy humans represent a heterogeneous and poorly studied subset. In this work, we analyzed this subset for…”
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Epithelial-Immune Cell Crosstalk Determines the Activation of Immune Cells In Vitro by the Human Cathelicidin LL-37 at Low Physiological Concentrations by Bogdanov, Ivan V, Streltsova, Maria A, Kovalenko, Elena I, Sapozhnikov, Alexander M, Panteleev, Pavel V, Ovchinnikova, Tatiana V

“…The only human cathelicidin, LL-37, is a host defense antimicrobial peptide with antimicrobial activities against protozoans, fungi, Gram(+) and Gram(−)…”
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Recurrent Stimulation of Natural Killer Cell Clones with K562 Expressing Membrane-Bound Interleukin-21 Affects Their Phenotype, Interferon-γ Production, and Lifespan by Streltsova, Maria A, Erokhina, Sofya A, Kanevskiy, Leonid M, Grechikhina, Maria V, Kobyzeva, Polina A, Lee, Dean A, Telford, William G, Sapozhnikov, Alexander M, Kovalenko, Elena I

“…A pattern of natural killer cell (NK cell) heterogeneity determines proliferative and functional responses to activating stimuli in individuals. Obtaining the…”
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Activation of α7 Nicotinic Acetylcholine Receptor Upregulates HLA-DR and Macrophage Receptors: Potential Role in Adaptive Immunity and in Preventing Immunosuppression by Siniavin, Andrei E, Streltsova, Maria A, Kudryavtsev, Denis S, Shelukhina, Irina V, Utkin, Yuri N, Tsetlin, Victor I

“…Immune response during sepsis is characterized by hyper-inflammation followed by immunosuppression. The crucial role of macrophages is well-known for both…”
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Obtaining Gene-Modified HLA-E-Expressing Feeder Cells for Stimulation of Natural Killer Cells by Alekseeva, Nadezhda A, Streltsova, Maria A, Vavilova, Julia D, Ustiuzhanina, Maria O, Palamarchuk, Anastasia I, Boyko, Anna A, Timofeev, Nikita D, Popodko, Alexey I, Kovalenko, Elena I

“…Human cytomegalovirus (HCMV)-specific adaptive NK cells are capable of recognizing viral peptides presented by HLA-E on infected cells via the NKG2C receptor…”
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Autologous T-Cell-Free Antigen Presentation System Unveils hCMV-Specific NK Cell Response by Ustiuzhanina, Maria O, Streltsova, Maria A, Timofeev, Nikita D, Kryukov, Maxim A, Chudakov, Dmitriy M, Kovalenko, Elena I

“…NK cells play a decisive role in controlling hCMV infection by combining innate and adaptive-like immune reactions. The hCMV-derived VMAPRTLFL (LFL) peptide is…”
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Three-Dimensional Model Analysis Revealed Differential Cytotoxic Effects of the NK-92 Cell Line and Primary NK Cells on Breast and Ovarian Carcinoma Cell Lines Mediated by Variations in Receptor-Ligand Interactions and Soluble Factor Profiles by Alekseeva, Nadezhda A, Boyko, Anna A, Shevchenko, Marina A, Grechikhina, Maria V, Streltsova, Maria A, Alekseeva, Ludmila G, Sapozhnikov, Alexander M, Deyev, Sergey M, Kovalenko, Elena I

“…The functional activity of a certain tumor determines the effectiveness of primary NK cells and NK-92 cell line-based cancer therapy; their therapeutic…”
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The Role of O-Antigen in LPS-Induced Activation of Human NK Cells by Kovalenko, Elena I., Telford, William G., Ziganshin, Rustam H., Streltsova, Maria A., Erokhina, Sofya A., Kanevskiy, Leonid M., Sapozhnikov, Alexander M.

“…NK cells can be stimulated by bacterial lipopolysaccharides (LPS). Unlike macrophages, human NK cells do not express or express very low level of surface TLR4…”
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Telomerase Reverse Transcriptase Increases Proliferation and Lifespan of Human NK Cells without Immortalization by Streltsova, Maria A., Ustiuzhanina, Maria O., Barsov, Eugene V., Kust, Sofya A., Velichinskii, Rodion A., Kovalenko, Elena I.

“…NK cells are the first line of defense against viruses and malignant cells, and their natural functionality makes these cells a promising candidate for cancer…”
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Phenotypic Changes in T and NK Cells Induced by Sputnik V Vaccination by Boyko, Anna A, Ustiuzhanina, Maria O, Vavilova, Julia D, Streltsova, Maria A, Kust, Sofya A, Siniavin, Andrei E, Astrakhantseva, Irina V, Drutskaya, Marina S, Kovalenko, Elena I

“…A highly effective humoral immune response induced by the Sputnik V vaccine was demonstrated in independent studies, as well as in large-scale post-vaccination…”
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